Journal ArticleDOI
Aquaporins: water channel proteins of the cell membrane
TLDR
The diverse and characteristic distribution of aquaporins in the body suggests their important and specific roles in each organ.About:
This article is published in Progress in Histochemistry and Cytochemistry.The article was published on 2004-05-25. It has received 371 citations till now. The article focuses on the topics: Aquaporin 2 & Aquaporin.read more
Citations
More filters
Journal ArticleDOI
Oogenesis in teleosts: How fish eggs are formed
TL;DR: Recent advances on teleost fish oocyte differentiation, maturation and ovulation are highlighted, including those involved in the degeneration and reabsorption of ovarian follicles (atresia).
Journal ArticleDOI
The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins.
Jun Adachi,Chanchal Kumar,Yanling Zhang,Yanling Zhang,Jesper V. Olsen,Jesper V. Olsen,Matthias Mann +6 more
TL;DR: The analysis provides a high-confidence set of proteins present in human urinary proteome and provides a useful reference for comparing datasets obtained using different methodologies and may prove useful in biomarker discovery in the future.
Journal ArticleDOI
Phylogeny and evolution of the major intrinsic protein family
TL;DR: This work states that with the recent increase in genomic projects, there is a considerable increase in the quantity and taxonomic range of MIPs in molecular databases.
Journal ArticleDOI
Theoretical aspects of water-holding in meat.
Eero Puolanne,Marjo Halonen +1 more
TL;DR: Irrespective of the lack of theoretical explanation on the mechanism of water-holding in meat, the meat industry is able to control the macroscopic behaviour of meat-based ingredients rather well and more attention should be paid to heavy meromyosin, Z-line and other elements of molecular size or colloidal size.
Journal ArticleDOI
Disruption of Aquaporin-11 Produces Polycystic Kidneys following Vacuolization of the Proximal Tubule
Yoshiyuki Morishita,Toshiyuki Matsuzaki,Mariko Hara-Chikuma,Ayaka Andoo,Mariko Shimono,Asako Matsuki,Katsuki Kobayashi,Masahiro Ikeda,Tadashi Yamamoto,Alan S. Verkman,Eiji Kusano,Shigeo Ookawara,Kuniaki Takata,Sei Sasaki,Kenichi Ishibashi +14 more
TL;DR: Data demonstrate that AQP11 is essential for the proximal tubular function and will provide a new mechanism for cystogenesis in polycystic kidney diseases.
References
More filters
Journal ArticleDOI
Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein.
TL;DR: Oocytes from Xenopus laevis microinjected with in vitro-transcribed CHIP28 RNA exhibited increased osmotic water permeability; this was reversibly inhibited by mercuric chloride, a known inhibitor of water channels, so it is likely that ChIP28 is a functional unit of membrane water channels.
Journal ArticleDOI
Structural determinants of water permeation through aquaporin-1.
Kazuyoshi Murata,Kaoru Mitsuoka,Teruhisa Hirai,Thomas Walz,Peter Agre,J. B. Heymann,Andreas Engel,Yoshinori Fujiyoshi +7 more
TL;DR: An atomic model of human red cell AQP1 is described, providing a possible molecular explanation to a longstanding puzzle in physiology—how membranes can be freely permeable to water but impermeable to protons.
Journal ArticleDOI
Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke.
Geoffrey T. Manley,Miki Fujimura,Tonghui Ma,Nobuo Noshita,Ferda Filiz,Andrew W. Bollen,Pak H. Chan,Alan S. Verkman +7 more
TL;DR: It is shown that mice deficient in aquaporin-4 (AQP4), a glial membrane water channel, have much better survival than wild-type mice in a model of brain edema caused by acute water intoxication, and suggested that AQP4 inhibition may provide a new therapeutic option for reducingbrain edema in a wide variety of cerebral disorders.
Journal ArticleDOI
Claudin-based tight junctions are crucial for the mammalian epidermal barrier a lesson from claudin-1–deficient mice
Mikio Furuse,Masaki Hata,Kyoko Furuse,Yoko Yoshida,Akinori Haratake,Yoshinobu Sugitani,Tetsuo Noda,Tetsuo Noda,Akiharu Kubo,Shoichiro Tsukita +9 more
TL;DR: Findings provide the first evidence that continuous claudin-based TJs occur in the epidermis and that these TJs are crucial for the barrier function of the mammalian skin.
Journal ArticleDOI
Specialized membrane domains for water transport in glial cells : high-resolution immunogold cytochemistry of aquaporin-4 in rat brain
Søren Nielsen,Erlend A. Nagelhus,Mahmood Amiry-Moghaddam,Charles W. Bourque,Peter Agre,Ole Petter Ottersen +5 more
TL;DR: The highly polarized AQP4 expression indicates that these cells are equipped with specific membrane domains that are specialized for water transport, thereby mediating the flow of water between glial cells and the cavities filled with CSF and the intravascular space.