Journal ArticleDOI
Blood neutrophil-to-lymphocyte ratio predicts survival in patients with unresectable hepatocellular carcinoma undergoing transarterial chemoembolization.
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TLDR
A high NLR independently predicts poor survival in patients with unresectable HCC undergoing transarterial chemoembolization treatment, and an increased NLR indicates a better outcome than a decreased NLR for patients after transarteria chemoEmbolization.About:
This article is published in Journal of Vascular and Interventional Radiology.The article was published on 2011-05-01. It has received 104 citations till now. The article focuses on the topics: Survival rate.read more
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Prognostic Role of Neutrophil-to-Lymphocyte Ratio in Solid Tumors: A Systematic Review and Meta-Analysis
Arnoud J. Templeton,Mairéad G McNamara,Bostjan Seruga,Francisco E. Vera-Badillo,Priya Aneja,Alberto Ocaña,Raya Leibowitz-Amit,Guru Sonpavde,Jennifer J. Knox,Ben Tran,Ian F. Tannock,Eitan Amir +11 more
TL;DR: A high NLR is associated with an adverse OS in many solid tumors, and its addition to established prognostic scores for clinical decision making warrants further investigation.
Journal ArticleDOI
The systemic inflammation-based neutrophil–lymphocyte ratio: Experience in patients with cancer
Graeme J.K. Guthrie,Kellie A. Charles,Campbell S.D. Roxburgh,Paul G. Horgan,Donald C. McMillan,Stephen Clarke +5 more
TL;DR: The present systematic review examines and comments on the clinical utility of the neutrophil-lymphocyte ratio, which has shown that NLR is elevated in patients with more advanced or aggressive disease evidenced by increased tumour stage, nodal stage, number of metastatic lesions and as such these patients may represent a particularly high-risk patient population.
Journal ArticleDOI
Prognostic Role of Platelet to Lymphocyte Ratio in Solid Tumors: A Systematic Review and Meta-Analysis
Arnoud J. Templeton,Olga Ace,Mairéad G McNamara,Mustafa Al-Mubarak,Francisco E. Vera-Badillo,Thomas Hermanns,Bostjan Seruga,Alberto Ocaña,Ian F. Tannock,Eitan Amir +9 more
TL;DR: A high PLR is associated with worse OS in various solid tumors and is a readily available and inexpensive biomarker with independent prognostic value in solid tumors.
Journal ArticleDOI
Preoperative neutrophil-to-lymphocyte ratio is a predictor of survival after hepatectomy for hepatocellular carcinoma: a retrospective analysis.
Yohei Mano,Ken Shirabe,Yo-ichi Yamashita,Norifumi Harimoto,Eiji Tsujita,Kazuki Takeishi,Shinichi Aishima,Toru Ikegami,Tomoharu Yoshizumi,Takeharu Yamanaka,Yoshihiko Maehara +10 more
TL;DR: NLR is an independent predictor of survival after hepatectomy in patients with HCC and accumulation of tumor-associated macrophages in the tumor is associated with a high NLR.
Journal ArticleDOI
Comparison of the prognostic value of inflammation-based prognostic scores in patients with hepatocellular carcinoma.
Akiyoshi Kinoshita,Hiroshi Onoda,Nami Imai,Akira Iwaku,Mutumi Oishi,Nao Fushiya,Kazuhiko Koike,Hirokazu Nishino,Hisao Tajiri +8 more
TL;DR: This study demonstrates that the Glasgow Prognostic Score, an inflammation-based prognostic score, is an independent marker of poor prognosis in patients with HCC and is superior to the other inflammation- based prognostic scores in terms of prognostic ability.
References
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Inflammation and cancer: back to Virchow?
TL;DR: A rationale for the use of cytokine and chemokine blockade, and further investigation of non-steroidal anti-inflammatory drugs, in the chemoprevention and treatment of malignant diseases is provided.
Journal ArticleDOI
Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome
Jérôme Galon,Anne Costes,Fátima Sánchez-Cabo,Amos Kirilovsky,Bernhard Mlecnik,Christine Lagorce-Pagès,Marie Tosolini,Matthieu Camus,Anne Berger,Philippe Wind,Franck Zinzindohoué,Patrick Bruneval,Paul-Henri Cugnenc,Zlatko Trajanoski,Wolf H. Fridman,Franck Pagès +15 more
TL;DR: In situ analysis of tumor-infiltrating immune cells may be a valuable prognostic tool in the treatment of colorectal cancer and possibly other malignancies.
Journal ArticleDOI
Clinical Management of Hepatocellular Carcinoma. Conclusions of the Barcelona-2000 EASL Conference
Jordi Bruix,Morris Sherman,Josep M. Llovet,Michel Beaugrand,Riccardo Lencioni,Andrew K. Burroughs,Erik Christensen,Luigi Pagliaro,Massimo Colombo,Juan Rodés +9 more
Journal ArticleDOI
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis
TL;DR: The matrix metalloproteinase MMP-9/gelatinase B is upregulated in angiogenic dysplasias and invasive cancers of the epidermis in a mouse model of multi-stage tumorigenesis elicited by HPV16 oncogenes, suggesting inflammatory cells can be coconspirators in carcinogenesis.
Journal Article
Ratio of neutrophil to lymphocyte counts--rapid and simple parameter of systemic inflammation and stress in critically ill.
TL;DR: In the population of 90 ICU oncological patients, rapid serial changes in white blood cell populations are observed, as a response of the immune system to surgical stress, systemic inflammation or sepsis.