Journal ArticleDOI
Bone regeneration using cell-mediated responsive degradable PEG-based scaffolds incorporating with rhBMP-2.
TLDR
The results indicated that both osteoinduction and appropriate degradation played a crucial role in accelerating and promoting bone augmentation, as well as effective proangiogenesis.About:
This article is published in Biomaterials.The article was published on 2013-02-01. It has received 90 citations till now. The article focuses on the topics: Bone regeneration.read more
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Bone biomaterials and interactions with stem cells.
TL;DR: A comprehensive review of the state of the art of bone biomaterials and their interactions with stem cells is presented and the promising seed stem cells for bone repair are summarized, and their interaction mechanisms are discussed in detail.
Journal ArticleDOI
Chitosan-based scaffolds for bone tissue engineering
TL;DR: This review discusses the fundamentals of bone tissue engineering and the unique properties of chitosan as a scaffolding material to treat bone defects for hard tissue regeneration, and discusses the influence of material preparation and addition of polymeric or ceramic components or biomolecules on chitOSan scaffold properties such as mechanical strength, structural integrity, and functional bone regeneration.
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3D printing of hydrogels: Rational design strategies and emerging biomedical applications
TL;DR: A review of hydrogel-based biomaterial inks and bioinks for 3D printing can be found in this paper, where the authors provide a comprehensive overview and discussion of the tailorability of material, mechanical, physical, chemical and biological properties.
Journal ArticleDOI
Glutathione responsive polymers and their application in drug delivery systems
TL;DR: A number of different strategies for the preparation of glutathione responsive materials are described, including the use of GSH responsive linkers to prepare polymers that degrade upon exposure to millimolar concentrations of G SH, and theUse of these polymers to prepare particles that disassemble at these concentrations.
Journal ArticleDOI
Latest Advances in Cryogel Technology for Biomedical Applications
Adnan Memic,Adnan Memic,Adnan Memic,Thibault Colombani,Loek J. Eggermont,Loek J. Eggermont,Mahboobeh Rezaeeyazdi,Joseph M Steingold,Zachary J. Rogers,Kasturi Joshi Navare,Halimatu S. Mohammed,Sidi A. Bencherif +11 more
TL;DR: In this paper, a review of the methods for synthesis and characterization of Cryogels is provided, highlighting key concepts relevant to cryogels and explaining their unique properties, as well as an in-depth overview of specific technologies and fields where they have been applied.
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Vascular endothelial growth factor: basic science and clinical progress.
TL;DR: Vascular endothelial growth factor (VEGF) is an endothelial cell-specific mitogen in vitro and an angiogenic inducer in a variety of in vivo models and is implicated in intraocular neovascularization associated with diabetic retinopathy and age-related macular degeneration.
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RGD modified polymers: biomaterials for stimulated cell adhesion and beyond
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Drug delivery strategy utilizing conjugation via reversible disulfide linkages: role and site of cellular reducing activities
TL;DR: This review focuses on understanding where and how the disulfide bond in the bioconjugate is reduced upon contact with biological milieu, which affects delivery design and the interpretation of the delivery strategies.
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Pathogenesis of lipoid nephrosis : a disorder of T-cell function
TL;DR: The data suggest that lipoid nephrosis is a clinical expression of a self-limited primary immune-deficiency disease that is of primary or secondary pathogenetic importance.
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Reduction-sensitive polymers and bioconjugates for biomedical applications.
TL;DR: This review presents recent advances in the development of reduction-sensitive biodegradable polymers and conjugates, with particular focus on the up-to-date design and chemistry of various reduction- sensitive delivery systems including liposome, polymersomes, polymeric micelles, DNA containing nanoparticles, polyion complex micells, nano- and micro-gels, nanotubes, and multi-layered thin films.