Journal ArticleDOI
Cellular defenses against damage from reactive oxygen species
TLDR
Ceruloplasmin should appear as follows: [See PDF]Abstract:
Pages 139–162: Yu. “Cellular Defenses Against Damage From Reactive Oxygen Species.” Page 150: The section 2. Ceruloplasmin should appear as follows: [See PDF]read more
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Levodopa in Parkinson's disease: neurotoxicity issue laid to rest?
TL;DR: Given that neither epidemiological nor clinical studies have ever provided evidence to support that long term levodopa administration can accelerate the progression of Parkinson’s disease, it is believed thatLevodopa therapy should not be delayed on the basis of an unconfirmed hypothesis.
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Brain antioxidant regulation in mammals and anoxia-tolerant reptiles: balanced for neuroprotection and neuromodulation.
TL;DR: Data indicate adaptations that prevent oxidative stress and suggest a particularly important role for ascorbate, and show that the antioxidant network must be balanced precisely to provide functional levels of ROS, as well as neuroprotection.
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Mitochondrial Genome Mutation in Cell Death and Aging
TL;DR: The total base sequencing of mtDNA among individuals revealed that germ-line point mutationstransmitted from ancestors accelerate the somatic oxygen damages and mutations in mtDNA leading to phenotypic expression of premature aging and degenerative diseases.
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Total Antioxidant Status at High Altitude in Lowlanders and Native Highlanders: Role of Uric Acid
TL;DR: A hypoxia-induced increase in UA contributes an appreciable portion of plasma total antioxidant capacity, but may not be effective in preventing oxidative stress at high altitude.
Journal ArticleDOI
Critical Evaluation of Gamma-Irradiated Serum Used as Feeder in the Culture and Demonstration of Putative Nanobacteria and Calcifying Nanoparticles
TL;DR: It is concluded that there is no basis to justify the use of γ-FBS as a feeder for the growth and demonstration of NB/CNP or any NB-like particles in culture, and the validity of the entire body of literature accumulated to date on NB and CNP is called into question.