Journal ArticleDOI
Cellular defenses against damage from reactive oxygen species
TLDR
Ceruloplasmin should appear as follows: [See PDF]Abstract:
Pages 139–162: Yu. “Cellular Defenses Against Damage From Reactive Oxygen Species.” Page 150: The section 2. Ceruloplasmin should appear as follows: [See PDF]read more
Citations
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Journal ArticleDOI
Oxidative stress and peritoneal endometriosis
TL;DR: Better understanding of the mechanisms of reactive oxygen species production and detoxification and further investigation of their effect on the peritoneal environment are essential to obtain new insight into this disease and eventually develop new diagnostic and therapeutic strategies.
Journal ArticleDOI
Thyroid hormone-induced oxidative stress.
Paola Venditti,S. Di Meo +1 more
TL;DR: Thyroid hormone-activated mitochondrial mechanisms provide protection against excessive tissue dysfunction, including increased expression of uncoupling proteins, proteolytic enzymes and transcriptional coactivator PGC-1, and stimulate opening of permeability transition pores.
Journal ArticleDOI
Oxidative Stress Signaling in Alzheimer’s Disease
Bo Su,Xinglong Wang,Akihiko Nunomura,Paula I. Moreira,H. Gon Lee,George Perry,Mark A. Smith,Xiongwei Zhu +7 more
TL;DR: An overview of the evidence of oxidative stress and compensatory responses that occur in AD is provided, particularly focused on potential sources of oxidative Stress and the roles and mechanism of activation of stress-activated protein kinase pathways.
Journal ArticleDOI
Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein.
Jefferson Y. Chan,Mandy Kwong +1 more
TL;DR: Overexpression of Nrf2 cDNA restored glutathione levels in nrf2(-/-) fibroblasts, which correlated with increased steady state levels of gcs(H) and gCS(L) transcripts, which establish a link between NRF2 transcription factor and GSH biosynthesis.
Book ChapterDOI
ATM: genome stability, neuronal development, and cancer cross paths.
Yosef Shiloh,Michael B. Kastan +1 more
TL;DR: Evidence that ATM is involved in signaling pathways other than those related to damage response, particularly ones relating to cellular growth and differentiation, reinforces the multifaceted nature of this protein, in which genome stability, developmental processes, and cancer cross paths.