Journal ArticleDOI
Cellular defenses against damage from reactive oxygen species
TLDR
Ceruloplasmin should appear as follows: [See PDF]Abstract:
Pages 139–162: Yu. “Cellular Defenses Against Damage From Reactive Oxygen Species.” Page 150: The section 2. Ceruloplasmin should appear as follows: [See PDF]read more
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Methylene blue induces cytotoxicity in human brain tumor cells
Yong Soo Lee,Robert D. Wurster +1 more
TL;DR: Results suggest that hydroxyl radical and intracellular Ca2+ may have an important involvement in the cytotoxic action of MB and suggest that the treatment with MB may be useful for the therapeutic applications of human brain tumors.
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Protective effects of black currant (Ribes nigrum L.) extract on hydrogen peroxide-induced damage in lung fibroblast MRC-5 cells in relation to the antioxidant activity
TL;DR: The protective effects of BCE on MRC-5 cells suggest that black currants may possess the ability to eliminate over-produced ROS in humans.
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Genotoxic stress-triggered β-catenin/JDP2/PRMT5 complex facilitates reestablishing glutathione homeostasis
Lixue Cao,Geyan Wu,Jinrong Zhu,Zhanyao Tan,Dongni Shi,Xingui Wu,Miaoling Tang,Ziwen Li,Yameng Hu,Shuxia Zhang,Ruyuan Yu,Shuang Mo,Jueheng Wu,Erwei Song,Mengfeng Li,Libing Song,Jun Li +16 more
TL;DR: A plausible role for β-catenin is unveiled in reestablishing redox homeostasis upon genotoxic stress and light is shed on the mechanisms of inducible chemotherapy resistance in cancer.
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Effects of landfill leachate effluent and bisphenol A on glutathione and glutathione-related enzymes in the gills and digestive glands of the freshwater snail Bellamya purificata
TL;DR: GST activity and total glutathione level, which showed dose-dependent dynamics, could be used as biomarkers of aquatic ecosystems contaminated with landfill leachate and BPA, respectively.
Journal ArticleDOI
Dietary restriction augments protection against induction of the mitochondrial permeability transition.
Bruce S. Kristal,Byung Pal Yu +1 more
TL;DR: Evidence that long-term, life-prolonging, dietary restriction regimens greatly delay induction of a PT following challenge is presented, and the observed effects represent one of the largest recognized dietary restriction-mediated increases in a parameter related to antioxidant defenses.