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Chem. Pharm. Bull.(オピニオン)
國郎 小笠原
- Vol. 43, Iss: 12, pp 1161
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The article was published on 2007-12-01 and is currently open access. It has received 1121 citations till now.read more
Citations
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Kinetic modeling on drug release from controlled drug delivery systems.
TL;DR: The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
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Fluorescent Sensors for Measuring Metal Ions in Living Systems
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Dietary phenolics: chemistry, bioavailability and effects on health.
TL;DR: This review summarizes the chemistry, biosynthesis and occurrence of the compounds involved, namely the C6-C3-C6 flavonoids-anthocyanins, dihydrochalcones, Flavan-3-ols, flavanones, flavones, Flavonols and isoflavones, and the mechanisms underlying these processes are discussed.
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Amide bond formation: beyond the myth of coupling reagents
Eric Valeur,Mark Bradley +1 more
TL;DR: This critical review is focussed on the most recently developed coupling reagents with particular attention paid to the pros and cons of the plethora of "acronym" based reagents.
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Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC
TL;DR: The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor and direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses.
References
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Journal ArticleDOI
3-Benzyl-amino-2-cyano-N-[N-(2-fluoro-phenyl)-carbamo-yl]-3-(methyl-sulfanyl)acryl-amide.
TL;DR: In the crystal structure of the title compound, C19H17FN4O2S, molecules are linked via pairs of N—H⋯N interactions, forming centrosymmetric dimers, which stabilize the molecular conformation.
Journal ArticleDOI
Crystal structure of (S)-2-amino-2-methyl-succinic acid.
TL;DR: The title compound, C5H9NO4, crystallized as a zwitterion, contains an intramolecular N—H⋯O hydrogen bond involving the trans-succinic acid and the ammonium group, forming an S(6) ring motif.
Journal ArticleDOI
Bis(2-amino-4-phenyl-1,3-thia-zol-3-ium) tetra-chlorido-palladate(II).
Reyna Reyes-Martínez,Rubén M. Carballo,Gonzalo J. Mena-Rejón,Simón Hernández-Ortega,David Cáceres-Castillo +4 more
TL;DR: The title compound, (C9H9N2S)2[PdCl4], consists of two monoprotonated 2-amino-4-phenyl-1,3-thiazole molecules and one tetrachloridopalladate anion.
Journal ArticleDOI
Marked therapeutic effects of hybrid liposomes on the hepatic metastasis of colon carcinoma
TL;DR: Optical microscopic analysis indicated that HLs could induce the apoptosis of colon carcinoma cells in vivo and Therapeutic effects along with the induction of apoptosis by HLs without any drugs on hepatic metastasis were revealed for the first time in vivo.
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5′′-(2-Fluorobenzylidene)-1′-(2-fluorophenyl)-1′′-methyl-1′,2′,3′,5′,6′,7′,8′,8a’-octahydrodispiro[acenaphthylene-1,3′-indolizine-2′,3′′-piperidine]-2,4′′(1H)-dione
TL;DR: In the title compound, C37H30Cl4N2O2, the pyridinone ring adopts a twisted half-chair conformation and the crystal packing is stabilized by C—H⋯π interactions.