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Chem. Pharm. Bull.(オピニオン)

國郎 小笠原
- Vol. 43, Iss: 12, pp 1161
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The article was published on 2007-12-01 and is currently open access. It has received 1121 citations till now.

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Kinetic modeling on drug release from controlled drug delivery systems.

Suvakanta Dash, +3 more
- 01 May 2010 - 
TL;DR: The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
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Fluorescent Sensors for Measuring Metal Ions in Living Systems

Kyle P. Carter, +2 more
- 03 Mar 2014 - 
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Dietary phenolics: chemistry, bioavailability and effects on health.

Alan Crozier, +2 more
- 22 Jul 2009 - 
TL;DR: This review summarizes the chemistry, biosynthesis and occurrence of the compounds involved, namely the C6-C3-C6 flavonoids-anthocyanins, dihydrochalcones, Flavan-3-ols, flavanones, flavones, Flavonols and isoflavones, and the mechanisms underlying these processes are discussed.
Journal ArticleDOI

Amide bond formation: beyond the myth of coupling reagents

Eric Valeur, +1 more
- 26 Jan 2009 - 
TL;DR: This critical review is focussed on the most recently developed coupling reagents with particular attention paid to the pros and cons of the plethora of "acronym" based reagents.
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Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC

Takashi Tanaka, +4 more
- 01 Jun 2007 - 
TL;DR: The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor and direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses.
References
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Carbon Nanotube Composites as Multifunctional Substrates for In Situ Actuation of Differentiation of Human Neural Stem Cells

John Landers, +6 more
- 01 Nov 2014 - 
TL;DR: Electrospun fibrous substrates with controlled fiber architectures provide topographical cues to cells by presenting three dimensional geometries that are representative of the extracellular matrix (ECM), and are thus better suited for differentiation studies of neural stem cells than standard two dimensional substrates.
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Diversity oriented syntheses of fused pyrimidines designed as potential antifolates

Colin L. Gibson, +9 more
- 07 May 2009 - 
TL;DR: Significant structural features required for inhibition of this important drug target enzyme have been identified and several compounds were found to inhibit pteridine reductases from the protozoan parasites Trypanosoma brucei and Leishmania major at the micromolar level.

Pharmacological studies of anticancer, anti inflammatory activities of Murraya koenigii (Linn) Spreng in experimental animals

P. Muthumani, +1 more
TL;DR: A significant decrease in the cancer cell number and tumour weight were noted in the tumour-induced mice after treatment with SU II, suggestive of the protective effect of extract in Dalton’s Ascitic Lymphoma (DAL).
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Benzopyran, biphenyl, and tetraoxygenated xanthone derivatives from the twigs of Garcinia nigrolineata.

Vatcharin Rukachaisirikul, +4 more
- 01 Aug 2005 - 
TL;DR: The xanthones isolated from the twigs as well as those from the stem bark were evaluated for antibacterial activity against methicillin-resistant Staphylococcus aureus and Nigrolineaxanthone F, latisxanthone D, and brasilixanthone showed significant activity.
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The rapid synthesis of oxazolines and their heterogeneous oxidation to oxazoles under flow conditions

Steffen Glöckner, +6 more
- 07 Jan 2015 - 
TL;DR: A rapid flow synthesis of oxazolines and their oxidation to the corresponding oxazoles is reported, using Deoxo-Fluor® to prepared at room temperature in a stereospecific manner.