Open Access
Chem. Pharm. Bull.(オピニオン)
國郎 小笠原
- Vol. 43, Iss: 12, pp 1161
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The article was published on 2007-12-01 and is currently open access. It has received 1121 citations till now.read more
Citations
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Selective inhibition of human brain tumor cells through multifunctional quantum-dot-based siRNA delivery.
Jongjin Jung,Aniruddh Solanki,Kevin A. Memoli,Ken-ichiro Kamei,Hiyun Kim,Michael A. Drahl,Lawrence J. Williams,Hsian-Rong Tseng,Ki-Bum Lee +8 more
TL;DR: To begin the development of the necessary treatment modalities, the nanomaterial-based siRNA delivery strategies must be demonstrated on oncogenes involved in cancer pathogenesis.
Journal Article
Immunoassay Methods and their Applications in Pharmaceutical Analysis: Basic Methodology and Recent Advances.
TL;DR: The basic methodologies and recent advances in immunoassay methods applied in different fields of pharmaceutical analysis have been reviewed.
Journal ArticleDOI
Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract
Yoriko Deguchi,Kouji Miyazaki +1 more
TL;DR: It is suggested that the chronic suppression of postprandial blood glucose elevation is important in preventing type 2 diabetes mellitus, and that Guava Leaf Tea is considered useful as an alimentotherapy for chronic treatment.
Journal ArticleDOI
Generator-based PET radiopharmaceuticals for molecular imaging of tumours: on the way to THERANOSTICS
Frank Rösch,Richard P. Baum +1 more
TL;DR: Generator-derived radionuclides for PET/CT imaging are promising for optimizing targeted radiotherapy by an individual patient-based approach, applying pre-therapeutic evaluation, as well as dosimetric calculations, and for measuring treatment response after Radionuclide therapy.
Journal ArticleDOI
Total synthesis of (+)-fawcettimine.
TL;DR: The fawcettimine class of Lycopodium alkaloids consists of over 60 natural products that typically contain a single quaternary carbon center and are derived biosynthetically from the lycopodane core through an oxidative rearrangement reaction.
References
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Journal Article
Kinetic modeling on drug release from controlled drug delivery systems.
TL;DR: The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
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Fluorescent Sensors for Measuring Metal Ions in Living Systems
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Dietary phenolics: chemistry, bioavailability and effects on health.
TL;DR: This review summarizes the chemistry, biosynthesis and occurrence of the compounds involved, namely the C6-C3-C6 flavonoids-anthocyanins, dihydrochalcones, Flavan-3-ols, flavanones, flavones, Flavonols and isoflavones, and the mechanisms underlying these processes are discussed.
Journal ArticleDOI
Amide bond formation: beyond the myth of coupling reagents
Eric Valeur,Mark Bradley +1 more
TL;DR: This critical review is focussed on the most recently developed coupling reagents with particular attention paid to the pros and cons of the plethora of "acronym" based reagents.
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Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC
TL;DR: The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor and direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses.