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Chem. Pharm. Bull.(オピニオン)

國郎 小笠原
- Vol. 43, Iss: 12, pp 1161
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The article was published on 2007-12-01 and is currently open access. It has received 1121 citations till now.

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A conventional new procedure for N-acylation of unprotected amino acids.

TL;DR: The overall yields of the target compounds were excellent, and this two-stage procedure could be applicable as an alternative procedure for one-pot reaction.
Dissertation

Metal catalysed cross-coupling reactions of heterocycles

Kirsty Adams
TL;DR: This report describes two methodology studies dedicated towards development of metal catalysed crosscoupling reactions in the synthesis of novel heterocyclic compounds and a new catalytic method for arylative spirocyclisation is reported.
Journal ArticleDOI

A selective and mild glycosylation method of natural phenolic alcohols.

TL;DR: ZnO–iodine has been identified as a new glycosylation promoter and successfully applied to the stereoselective glycoside synthesis and the final products were obtained by conventional Zemplén deacetylation.
Journal ArticleDOI

Canarosine: a new guanidine alkaloid from Canavalia rosea with inhibitory activity on dopamine D1 receptors.

TL;DR: A new acyclic guanidine alkaloid, canarosine, together with five known compounds, β-sitosterol, stigmasterol, daucosterol , epi-inositol 6-O-methyl ether, and rutin, were isolated from the aerial parts of Canavalia rosea and their structures were established on the basis of their spectroscopic data.
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Rossicasins A, B and rosicaside F, three new phenylpropanoid glycosides from Boschniakia rossica.

TL;DR: Three phenylpropanoid glycosides have been isolated from the aqueous extract of Boschniakia rossica and this is the first isolation from a natural source.
References
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Kinetic modeling on drug release from controlled drug delivery systems.

TL;DR: The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
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Dietary phenolics: chemistry, bioavailability and effects on health.

TL;DR: This review summarizes the chemistry, biosynthesis and occurrence of the compounds involved, namely the C6-C3-C6 flavonoids-anthocyanins, dihydrochalcones, Flavan-3-ols, flavanones, flavones, Flavonols and isoflavones, and the mechanisms underlying these processes are discussed.
Journal ArticleDOI

Amide bond formation: beyond the myth of coupling reagents

TL;DR: This critical review is focussed on the most recently developed coupling reagents with particular attention paid to the pros and cons of the plethora of "acronym" based reagents.
Journal ArticleDOI

Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC

TL;DR: The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor and direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses.