Open Access
Chem. Pharm. Bull.(オピニオン)
國郎 小笠原
- Vol. 43, Iss: 12, pp 1161
Reads0
Chats0
About:
The article was published on 2007-12-01 and is currently open access. It has received 1121 citations till now.read more
Citations
More filters
Journal ArticleDOI
Aldose reductase and advanced glycation endproducts inhibitory effect of Phyllostachys nigra.
TL;DR: Luteolin 6-C-(6''-O-trans-caffeoylglucoside) (6), a flavone of this plant, have antioxidative as well as aldose reductase and advanced glycation endproducts inhibitory effects and could be offered as a leading compound for further study as a new natural products drug for diabetic complications.
Journal Article
Can nausea and vomiting be treated with ginger extract
Attilio Giacosa,Paolo Morazzoni,E. Bombardelli,Antonella Riva,G. Bianchi Porro,Mariangela Rondanelli +5 more
TL;DR: A systematic review of double-blind, placebo-controlled, randomized studies highlighted the potential efficacy of ginger on the prevention and treatment of nausea and vomiting of various origins, even though additional controlled studies are needed, and hypothesizes a therapeutic role for ginger extracts in case of side effects.
Journal ArticleDOI
Quantitative determination of four diterpenoids in Radix Salviae Miltiorrhizae using LC-MS-MS.
TL;DR: The established HPLC-ESI-MS-MS method developed for the quantitative determination of four diterpenoids was successfully applied to the quality assessment of seven batches of RSM samples collected from different regions of China.
Journal ArticleDOI
Fraxinellone inhibits lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by negatively regulating nuclear factor-kappa B in RAW 264.7 macrophages cells.
Jong-Hwan Kim,Young-Mi Park,Ji-Sun Shin,Seung Jae Park,Jung-Hye Choi,Hyun-Ju Jung,Hee-Juhn Park,Kyung-Tae Lee +7 more
TL;DR: The results suggest that the anti-inflammatory properties of fraxinellone are related to the down-regulations of iNOS and COX-2 due to NF-kappaB inhibition through the negative regulations of IKK and ERK1/2 phosphorylations in RAW 264.7 cells.
Journal ArticleDOI
Prodrugs for the treatment of neglected diseases.
Man Chin Chung,Elizabeth Igne Ferreira,Jean Leandro dos Santos,Jeanine Giarolla,Daniela Gonçales Rando,Adélia Emília Almeida,Priscila Longhin Bosquesi,Renato Farina Menegon,Lorena Blau +8 more
TL;DR: The present review covers 20 years of research on the design of prodrugs for the treatment of neglected and extremely neglected diseases such as Chagas’ disease (American trypanosomiasis), sleeping sickness, sleeping sickness), malaria, sickle cell disease, tuberculosis, leishmaniasis and schisto-miasis.
References
More filters
Journal Article
Kinetic modeling on drug release from controlled drug delivery systems.
TL;DR: The mathematical modeling can ultimately help to optimize the design of a therapeutic device to yield information on the efficacy of various release models.
Journal ArticleDOI
Fluorescent Sensors for Measuring Metal Ions in Living Systems
Journal ArticleDOI
Dietary phenolics: chemistry, bioavailability and effects on health.
TL;DR: This review summarizes the chemistry, biosynthesis and occurrence of the compounds involved, namely the C6-C3-C6 flavonoids-anthocyanins, dihydrochalcones, Flavan-3-ols, flavanones, flavones, Flavonols and isoflavones, and the mechanisms underlying these processes are discussed.
Journal ArticleDOI
Amide bond formation: beyond the myth of coupling reagents
Eric Valeur,Mark Bradley +1 more
TL;DR: This critical review is focussed on the most recently developed coupling reagents with particular attention paid to the pros and cons of the plethora of "acronym" based reagents.
Journal ArticleDOI
Facile Discrimination of Aldose Enantiomers by Reversed-Phase HPLC
TL;DR: The reaction was applied to the determination of absolute configuration the sugar residues of an aroma precursor and direct HPLC analysis of the reaction mixture and UV detection at 250 nm discriminated D- and L-enantiomers of aldoses.