Chikungunya virus, southeastern France.
Marc Grandadam,Valérie Caro,Sébastien Plumet,Jean Michel Thiberge,Yvan Souares,Anna-Bella Failloux,Hugues Tolou,Michel Budelot,Didier Cosserat,Isabelle Leparc-Goffart,Philippe Desprès +10 more
TLDR
Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the chikungunya virus in Europe.Abstract:
In September 2010, autochthonous transmission of chikungunya virus was recorded in southeastern France, where the Aedes albopictus mosquito vector is present. Sequence analysis of the viral genomes of imported and autochthonous isolates indicated new features for the potential emergence and spread of the virus in Europe.read more
Citations
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Chikungunya: Resurgent Arbovirus and its Impact in Brazil
TL;DR: The Chikungunya virus (CHIKV) is an alphavirus transmitted by the bite of blood-sucking mosquitoes and causes a significant public health problem in tropical and subtropical regions.
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Epidemiology and Economic Burden of Chikungunya: A Systematic Literature Review
Lourrany B. Costa,Francisca Kalline de Almeida Barreto,Marina Carvalho Arruda Barreto,Thyago Henrique Pereira dos Santos,Luís Arthur Brasil Gadelha Farias,André Ricardo Ribas Freitas,Miguel J. Martínez,Luciano Pamplona de Góes Cavalcanti +7 more
TL;DR: In this article , a review of the global epidemiological and economic burden of chikungunya is presented, which includes studies published from 2007 to 2022 in MEDLINE, Embase, LILACS, and SciELO for a thorough evaluation of the literature.
Clearance of an Arthritogenic Alphavirus Macrophages and Neutrophils Enhances Genetic Ablation of Arginase 1 in
Thomas E. Morrison,Stephanie A. Montgomery,Luke B. Borst,Ronald G. Gill,Kristina A. Stoermer,Adam L. Burrack +5 more
TL;DR: It is found that RRV- and CHIKV-induced musculoskeletal inflammatory lesions, and macrophages present in these lesions, have a unique gene-expression pattern characterized by high expression of arginase 1 and Ym1/Chi3l3 in the absence of FIZZ1/Relm a that is consistent with an M2-like activation phenotype.
References
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Infection with chikungunya virus in Italy: an outbreak in a temperate region
Giovanni Rezza,Loredana Nicoletti,R Angelini,Roberto Romi,A C Finarelli,M. Panning,Paolo Cordioli,Claudia Fortuna,S. Boros,Fabio Magurano,G. Silvi,Paola Angelini,Michele Dottori,Maria Grazia Ciufolini,Giancarlo Majori,Antonio Cassone +15 more
TL;DR: In this article, an outbreak of chikungunya virus (CHIKV) was reported in Italy, where the primary source of infection and modes of transmission were identified and an active surveillance system was also implemented.
Journal ArticleDOI
A single mutation in chikungunya virus affects vector specificity and epidemic potential.
TL;DR: The observation that a single amino acid substitution can influence vector specificity provides a plausible explanation of how this mutant virus caused an epidemic in a region lacking the typical vector, and has important implications with respect to how viruses may establish a transmission cycle when introduced into a new area.
Journal ArticleDOI
Present and future arboviral threats.
TL;DR: Viruses such as dengue (DENV) and chikungunya (CHIKV) that have lost the requirement for enzootic amplification now produce extensive epidemics in tropical urban centers, and climate warming could facilitate the expansion of the distributions of many arboviruses.
Journal ArticleDOI
Genome Microevolution of Chikungunya Viruses Causing the Indian Ocean Outbreak
Isabelle Schuffenecker,Isabelle Iteman,Alain Michault,Séverine Murri,Lionel Frangeul,Marie-Christine Vaney,Marie-Christine Vaney,Rachel Lavenir,Nathalie Pardigon,Jean-Marc Reynes,François Pettinelli,Leon Biscornet,Laure Diancourt,Stéphanie Michel,Stéphane Duquerroy,Stéphane Duquerroy,Stéphane Duquerroy,Ghislaine Guigon,Marie-Pascale Frenkiel,Anne-Claire Brehin,Nadège Cubito,Philippe Desprès,Frank Kunst,Félix A. Rey,Félix A. Rey,Hervé Zeller,Sylvain Brisse +26 more
TL;DR: The results indicate that the chikungunya virus outbreak was initiated by a strain related to East-African isolates, from which viral variants have evolved following a traceable microevolution history and may be due to adaptation to the mosquito vector.
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