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Community-Acquired Urinary Tract Infection by Escherichia coli in the Era of Antibiotic Resistance.

TLDR
This review is to ensure that clinicians understand the current seriousness of antibiotic-resistant E. coli, the mechanisms by which resistance is selected for, and methods that can be used to prevent antibiotic resistance.
Abstract
Urinary tract infections (UTIs) caused by Escherichia coli (E. coli) are the most common types of infections in women. The antibiotic resistance of E. coli is increasing rapidly, causing physicians to hesitate when selecting oral antibiotics. In this review, our objective is to ensure that clinicians understand the current seriousness of antibiotic-resistant E. coli, the mechanisms by which resistance is selected for, and methods that can be used to prevent antibiotic resistance.

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Medicinal plants: Treasure trove for green synthesis of metallic nanoparticles and their biomedical applications

TL;DR: The simplified model summarises the green synthesis, its characterization using physicochemical means and their biomedical applications, and discusses the recent advances in green synthesis of metallic nanoparticles, milestones, therapeutic applications and future perspectives of biosynthesized nanoparticles from some important medicinal plants.
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Antimicrobial resistance in community-acquired urinary tract infections in Paris in 2015.

TL;DR: The prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) bacteriuria seems to be 4%, and older age, immunosuppression, recurrent UTI, recent hospitalization, and antibiotic therapy are the main risk factors associated with ESBL- PE community-acquired UTI.
Journal ArticleDOI

Molecular characterization of Extended-spectrum β lactamase- producing E. coli recovered from community-acquired urinary tract infections in Upper Egypt

TL;DR: Alarming evidence of a serious spread of ESBL genes in Egypt, especially the epidemiological CTX-M 15, with the potential for the dissemination of MDR UPEC strains in the community is presented.
Journal ArticleDOI

Synthetic Glycans to Improve Current Glycoconjugate Vaccines and Fight Antimicrobial Resistance

TL;DR: An overview of structure–immunogenicity relationships from available data is built to better exploit the peculiar role of carbohydrates as vaccine targets and create the next generation of synthetic carbohydrate-based vaccines.
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Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat

TL;DR: β-Lactamases continue to be the leading cause of resistance to β-lactam antibiotics among gram-negative bacteria and are now found in a significant percentage of Escherichia coli and Klebsiella pneumoniae strains in certain countries.
Journal ArticleDOI

Carbapenemases: the versatile beta-lactamases.

TL;DR: The characteristics, epidemiology, and detection of the carbapenemases found in pathogenic bacteria are updates and metallo-β-lactamases are detected primarily in Pseudomonas aeruginosa.
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