Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis.
Tabea Schoeler,Anna M. Monk,Musa Sami,Ewa Klamerus,Enrico Foglia,Ruth Brown,Giulia Camuri,A. Carlo Altamura,Robin M. Murray,Sagnik Bhattacharyya +9 more
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TLDR
Continued cannabis use after onset of psychosis predicts adverse outcome, including higher relapse rates, longer hospital admissions, and more severe positive symptoms than for individuals who discontinue cannabis use and those who are non-users.About:
This article is published in The Lancet Psychiatry.The article was published on 2016-03-01 and is currently open access. It has received 232 citations till now. The article focuses on the topics: Cannabis & Substance abuse.read more
Citations
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The pharmacokinetics and the pharmacodynamics of cannabinoids.
TL;DR: The limited availability of applicable pharmacokinetic and pharmacodynamic information highlights the need to initiate prescribing cannabis medicines using a 'start low and go slow' approach, carefully observing the patient for desired and adverse effects.
Journal ArticleDOI
Traditional marijuana, high-potency cannabis and synthetic cannabinoids: increasing risk for psychosis.
TL;DR: Irrespective of whether use of cannabis is decriminalized or legalized, the evidence that it is a component cause of psychosis is now sufficient for public health messages outlining the risk, especially of regular use of high‐potency cannabis and synthetic cannabinoids.
Journal ArticleDOI
Assessing the public health impacts of legalizing recreational cannabis use: the US experience.
TL;DR: It appears to have increased the frequency of cannabis use among adults, but not so far among youth, and the impact of legalizing adult recreational use on cannabis price, availability, potency and use; and regulatory policies that may increase or limit adverse effects of legalization is reviewed.
Journal ArticleDOI
Cannabis, cannabinoids, and health.
TL;DR: The objective of this article is to summarize current developments concerning cannabis and the spread of synthetic cannabinoid (SC) use, and to further explore the benefit-risk profile of medical cannabis use.
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Cannabis and mental illness: a review
Darby J. E. Lowe,Darby J. E. Lowe,Julia Sasiadek,Alexandria S. Coles,Tony P. George,Tony P. George +5 more
TL;DR: This article provides a reconciliation of the addiction vulnerability and allostatic hypotheses to explain co-morbidity addiction in mentally ill cannabis users, as well as to further aid in developing a rational framework for the assessment and treatment of problematic cannabis use in these patients.
References
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Statistical Power Analysis for the Behavioral Sciences
TL;DR: The concepts of power analysis are discussed in this paper, where Chi-square Tests for Goodness of Fit and Contingency Tables, t-Test for Means, and Sign Test are used.
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Bias in meta-analysis detected by a simple, graphical test
TL;DR: Funnel plots, plots of the trials' effect estimates against sample size, are skewed and asymmetrical in the presence of publication bias and other biases Funnel plot asymmetry, measured by regression analysis, predicts discordance of results when meta-analyses are compared with single large trials.
Book
Cochrane Handbook for Systematic Reviews of Interventions
Julian P T Higgins,Sally Green +1 more
TL;DR: The Cochrane Handbook for Systematic Reviews of Interventions is the official document that describes in detail the process of preparing and maintaining Cochrane systematic reviews on the effects of healthcare interventions.
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