Distribution and location of genetic effects for dairy traits
John B. Cole,Paul M. VanRaden,Jeffrey R. O'Connell,C.P. Van Tassell,Tad S. Sonstegard,Robert D. Schnabel,Jeremy F. Taylor,G.R. Wiggans +7 more
TLDR
A high-density scan using 38,416 single nucleotide polymorphism markers for 5,285 bulls confirmed 2 previously known major genes on Bos taurus autosomes (BTA) 6 and 14 but revealed few other large effects as discussed by the authors.About:
This article is published in Journal of Dairy Science.The article was published on 2009-06-01 and is currently open access. It has received 224 citations till now. The article focuses on the topics: Quantitative trait locus & Allele.read more
Citations
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Identification of Genomic Differences between Hanwoo and Holstein Breeds Using the Illumina Bovine SNP50 BeadChip
TL;DR: The rate of polymorphisms detected in these two breeds suggests that the SNPs can be used for different applications, such as whole-genome association and comparative genetic studies, and are a helpful tool in developing breed identification genetic markers.
Journal ArticleDOI
Identification of Single Nucleotide Polymorphism from Indian Bubalus bubalis through Targeted Sequence Capture
Arun Patel,R. B. Subramanian,Harish Padh,Tarpan Shah,Amitbikram Mohapatra,Bhaskar Reddy,Subhash J. Jakhesara,Prakash G. Koringa,Debabrata Dash,Chaitanya G. Joshi +9 more
TL;DR: A. B. Patel 1,2, R. G. Joshi 2, * BRD School of Biosciences, Sardar Patel University, V. V. Nagar 388 120, India Department of Animal Biotechnology, College of Veterinary Science and Animal Husbandry, Anand Agricultural University and Roche Diagnostics India Pvt Ltd, Kolkata 700 107, India
Journal ArticleDOI
Genomic selection in multi-breed dairy cattle populations
TL;DR: Additional research is needed to determine the value of multi-breed reference populations for composite and synthetic breeds that include both indicine and taurine cattle adapted to tropical climates.
Journal ArticleDOI
Theoretical and empirical comparisons of expected and realized relationships for the X-chromosome
Tom Druet,Andres Legarra +1 more
TL;DR: This work shows theoretically and empirically that a pedigree-based relationship matrix built with rules specifically developed for the X-chromosome ( S ) matches the realized GRM for theX- Chromosome, and recommends that applications that combine expected relationships and genotypes for markers on the x-chromOSome should use S and G X.
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Characterization of functional traits with focus on udder health in heifers with divergent paternally inherited haplotypes on BTA18
A. Heimes,J. Brodhagen,Rosemarie Weikard,Harald M. Hammon,Marie M. Meyerholz,Wolfram Petzl,Holm Zerbe,Susanne Engelmann,Marion Schmicke,Martina Hoedemaker,Hans-Joachim Schuberth,Christa Kühn,Christa Kühn +12 more
TL;DR: The original article [1] contained an error whereby the captions to Figs 2 and 3 were mistakenly inverted; this has now been corrected.
References
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Book
Introduction to quantitative genetics
TL;DR: The genetic constitution of a population: Hardy-Weinberg equilibrium and changes in gene frequency: migration mutation, changes of variance, and heritability are studied.
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Prediction of Total Genetic Value Using Genome-Wide Dense Marker Maps
TL;DR: It was concluded that selection on genetic values predicted from markers could substantially increase the rate of genetic gain in animals and plants, especially if combined with reproductive techniques to shorten the generation interval.
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Efficient Methods to Compute Genomic Predictions
TL;DR: Efficient methods for processing genomic data were developed to increase reliability of estimated breeding values and to estimate thousands of marker effects simultaneously, and a blend of first- and second-order Jacobi iteration using 2 separate relaxation factors converged well for allele frequencies and effects.
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Invited review: reliability of genomic predictions for North American Holstein bulls.
Paul M. VanRaden,C.P. Van Tassell,G.R. Wiggans,Tad S. Sonstegard,Robert D. Schnabel,Jeremy F. Taylor,Flavio S Schenkel +6 more
TL;DR: Genotypes for 38,416 markers and August 2003 genetic evaluations for 3,576 Holstein bulls born before 1999 were used to predict January 2008 daughter deviations and genomic prediction improves reliability by tracing the inheritance of genes even with small effects.