Do trans fatty acids from industrially produced sources and from natural sources have the same effect on cardiovascular disease risk factors in healthy subjects? Results of the trans Fatty Acids Collaboration (TRANSFACT) study.
Jean Michel Chardigny,Frédéric Destaillats,Corinne Malpuech-Brugère,Julie Moulin,Dale E. Bauman,Adam L. Lock,Dave M. Barbano,Ronald P. Mensink,Jean Baptiste Bezelgues,Patrice Chaumont,Nicole Combe,Isabelle Cristiani,Florent Joffre,J. Bruce German,Fabiola Dionisi,Yves Boirie,Jean Louis Sébédio +16 more
TLDR
This study shows that TFAs from industrially produced and from natural sources have different effects on CVD risk factors in women, and the HDL cholesterol-lowering property of TFAs seems to be specific to industrial sources.About:
This article is published in The American Journal of Clinical Nutrition.The article was published on 2008-03-01 and is currently open access. It has received 259 citations till now. The article focuses on the topics: Lipoprotein particle.read more
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Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol
TL;DR: This Opinion of the EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA) deals with the setting of Dietary Reference Values (DRVs) for fats and it was decided not to propose a reference value beside the limitation on the intake of SFA.
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Red meat consumption: an overview of the risks and benefits.
Alison J. McAfee,Emeir M. McSorley,Geraldine Cuskelly,Bruce W. Moss,Julie M. W. Wallace,Maxine P. Bonham,Anna M Fearon +6 more
TL;DR: Moderate consumption of lean red meat as part of a balanced diet is unlikely to increase risk for CVD or colon cancer, but may positively influence nutrient intakes and fatty acid profiles, thereby impacting positively on long-term health.
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Health effects of trans-fatty acids: experimental and observational evidence.
TL;DR: Controlled trials and observational studies provide concordant evidence that consumption of TFA from partially hydrogenated oils adversely affects multiple cardiovascular risk factors and contributes significantly to increased risk of CHD events.
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Reduction in saturated fat intake for cardiovascular disease
TL;DR: There was some evidence that reducing saturated fats reduced the risk of myocardial infarction, but effects on all-cause mortality and cardiovascular morbidity were less clear, and there were suggestions of greater protection with greater saturated fat reduction or greater increase in polyunsaturated and monounsaturated fats.
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Components of a cardioprotective diet: new insights.
TL;DR: The need to prioritize selected foods and overall dietary patterns rather than only individual nutrients, the relevance of carbohydrate and fat quality as well as quantity, the effects and policy implications of sodium consumption, the importance of energy balance, and the role of dietary supplements represent several key findings of interest.
References
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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
Journal Article
Detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III)
Scott M. Grundy,Diane M. Becker,Luther T. Clark,Richard S. Cooper,Margo A. Denke,James P. Howard,Donald B. Hunninghake,D. Roger Illingworth,Russell V. Luepker,Patrick E. McBride,James M. McKenney,Richard C. Pasternak,Neil J. Stone,Linda Van Horn +13 more
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Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
TL;DR: The effects of dietary fats on total:HDL cholesterol may differ markedly from their effects on LDL, and the effects of fats on these risk markers should not in themselves be considered to reflect changes in risk but should be confirmed by prospective observational studies or clinical trials.
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Trans Fatty Acids and Cardiovascular Disease
TL;DR: The authors consider the feasibility and potential implications of reducing or eliminating the consumption of trans fatty acids from partially hydrogenated vegetable oils in the United States.