Open AccessJournal Article
Ectopic vascularized bone formation by human mesenchymal stem cell microtissues in a biocomposite scaffold B Biointerfaces
Rajan Narayan,Tarun Agarwal,Debasish Mishra,Somnath Maji,Sujata Mohanty,Asok Mukhopadhyay,Tapas K. Maiti +6 more
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TLDR
In this paper, the potential of three-dimensional multicellular human bone marrow mesenchymal stem cells (hBM-MSCs) in combination with a biocomposite material to form vascularized bone-like tissue at an ectopic site in an immunocompromised mouse was evaluated.About:
This article is published in Colloids and Surfaces.The article was published on 2017-01-01 and is currently open access. It has received 14 citations till now. The article focuses on the topics: Bone tissue & Mesenchymal stem cell.read more
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Bone tissue engineering: Scaffold preparation using chitosan and other biomaterials with different design and fabrication techniques
TL;DR: This review aims to provide an overview of different types of fabrication techniques for scaffold preparation in bone tissue engineering using biological macromolecules.
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Highly Porous Microcarriers for Minimally Invasive In Situ Skeletal Muscle Cell Delivery.
Ranjith Kumar Kankala,Jia Zhao,Chen-Guang Liu,Xiao-Jie Song,Da-Yun Yang,Kai Zhu,Shi-Bin Wang,Yu Shrike Zhang,Ai-Zheng Chen +8 more
TL;DR: In vivo results in mice confirm improved cell retention and vascularization, as well as partial myoblast differentiation in these modular cell-laden microcarriers potentially allow for in situ tissue construction after minimally invasive delivery providing a convenient means for regeneration medicine.
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Electroconductive multi-functional polypyrrole composites for biomedical applications
Ehsan Nazarzadeh Zare,Tarun Agarwal,Atefeh Zarepour,Filippo Pinelli,Ali Zarrabi,Filippo Rossi,Milad Ashrafizadeh,Aziz Maleki,Mohammad-Ali Shahbazi,Tapas K. Maiti,Rajender S. Varma,Franklin R. Tay,Michael R. Hamblin,Virgilio Mattoli,Pooyan Makvandi +14 more
TL;DR: Polypyrrole is an example of inherently electrically conductive polymer that is employed in the biomedical arena because of its low cost, excellent electroconductive properties, and good biocompatibility as mentioned in this paper.
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Insights into the angiogenic effects of nanomaterials: mechanisms involved and potential applications
TL;DR: This review focuses on the angiogenic effects of nanoscaffolds in different types of tissue regeneration and discusses the influencing factors as well as possible related mechanisms of nanomaterials in endothelial neovascularization.
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Waiting for Aπαταω: 250 Years Later.
Victoria M. Wu,Vuk Uskoković +1 more
TL;DR: It is celebrated 250 years since the discovery of the chemical identity of the inorganic component of bone in 1769 by Johan Gottlieb Gahn through one such imaginary dialogue between two seasoned researchers and aficionados of this material.
References
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Three-dimensional scaffolds for tissue engineering applications : role of porosity and pore size
Qiu Li Loh,Cleo Choong +1 more
TL;DR: The ability of pore size and porosity of scaffolds to direct cellular responses and alter the mechanical properties of scaffold will be reviewed, followed by a look at nature's own scaffold, the extracellular matrix.
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The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering
TL;DR: The results show that cell number was highest in scaffolds with the largest pore size, which was deemed optimal for bone tissue engineering, and an added advantage of the larger pores is a reduction in cell aggregations that develop along the edges of the scaffolds.
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Mesenchymal stem cells: immune evasive, not immune privileged
TL;DR: Protecting MSCs from immune detection and prolonging their persistence in vivo may improve clinical outcomes and prevent patient sensitization toward donor antigens.
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The mechanism of mineralization and the role of alkaline phosphatase in health and disease.
TL;DR: Although hypophosphatasia is untreatable at present, the recent success of enzyme replacement therapy offers promise, and strategies for preventing pathologic calcification using TNAP and NPP1 are in development.
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Bone Regeneration Based on Tissue Engineering Conceptions — A 21st Century Perspective
Jan Henkel,Maria A. Woodruff,Devakara R. Epari,Roland Steck,Vaida Glatt,Ian C. Dickinson,Peter F. M. Choong,Michael Schuetz,Dietmar W. Hutmacher +8 more
TL;DR: Bone Tissue Engineering has been the topic of substantial research over the past two decades as mentioned in this paper, and recent advances in the development of biomaterials have provided attractive alternatives to bone grafting expanding the surgical options for restoring the form and function of injured bone.