Journal ArticleDOI
Etchable SERS nanosensor for accurate pH and hydrogen peroxide sensing in living cells.
TLDR
A "turning off" strategy by combining etchable SERS nanosensors with a non-permeable etchant is proposed, allowing accurate intracellular pH and H2O2 sensing.About:
This article is published in Chemical Communications.The article was published on 2019-10-24. It has received 21 citations till now. The article focuses on the topics: Cell outer membrane & Nanosensor.read more
Citations
More filters
Journal ArticleDOI
SERS Tags for Biomedical Detection and Bioimaging
TL;DR: The building blocks of SERS tags are introduced, followed by the summarization of recent progress in Sers tags employed for detecting biomarkers, such as DNA, miRNA, and protein in biological fluids, as well as imaging from in vitro cell, bacteria, tissue to in vivo tumors.
Journal ArticleDOI
Real-time photoelectrochemical quantification of hydrogen peroxide produced by living cells
TL;DR: In this article, a novel p-type semiconductor-based photoelectrochemical (PEC) sensor was demonstrated to effectively trigger H2O2 reduction to exclude the interferences of other reactive species that co-exist in the biosystem.
Journal ArticleDOI
Intracellular pH - Advantages and pitfalls of surface-enhanced Raman scattering and fluorescence microscopy - A review.
TL;DR: In this paper, the authors described intracellular pH measurements using two most sensitive optical spectroscopies: surface-enhanced Raman scattering (SERS) and fluorescence.
Journal ArticleDOI
From single cells to complex tissues in applications of surface-enhanced Raman scattering
TL;DR: The aim of this tutorial review is to better facilitate the transition from single cells to complex tissues by demonstrating the similarities in the methodologies that have been used and how to overcome some of the challenges of working with tissue.
Journal ArticleDOI
Application of molecular SERS nanosensors: where we stand and where we are headed towards?
TL;DR: The present article gives the readership an overview of the present research advancements in the field of molecular SERS sensors, highlighting future trends.
References
More filters
Journal ArticleDOI
Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS)
Katrin Kneipp,Katrin Kneipp,Yang Wang,Yang Wang,Harald Kneipp,Harald Kneipp,Lev T. Perelman,Lev T. Perelman,Irving Itzkan,Irving Itzkan,Ramachandra R. Dasari,Ramachandra R. Dasari,Michael S. Feld,Michael S. Feld +13 more
TL;DR: In this article, the first observation of single molecule Raman scattering was made using a single crystal violet molecule in aqueous colloidal silver solution using one second collection time and about $2.
Journal ArticleDOI
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
Michael T. Lin,M. Flint Beal +1 more
TL;DR: Treatments targeting basic mitochondrial processes, such as energy metabolism or free-radical generation, or specific interactions of disease-related proteins with mitochondria hold great promise in ageing-related neurodegenerative diseases.
Journal ArticleDOI
Reactive oxygen species have a causal role in multiple forms of insulin resistance.
TL;DR: A genomic analysis of two cellular models of insulin resistance, one induced by treatment with the cytokine tumour-necrosis factor-α and the other with the glucocorticoid dexamethasone, suggests that reactive oxygen species levels are increased in both models, and increased ROS levels are an important trigger for insulin resistance in numerous settings.
Journal ArticleDOI
SERS Nanoparticles in Medicine: From Label-Free Detection to Spectroscopic Tagging.
TL;DR: Spectroscopic Tagging helps clarify the role of X-ray diffraction in the determination of Higgs boson levels in the response of EMTs to injury.
Journal ArticleDOI
Triton X-100 concentration effects on membrane permeability of a single HeLa cell by scanning electrochemical microscopy (SECM)
Dipankar Koley,Allen J. Bard +1 more
TL;DR: Changes in HeLa cell morphology, membrane permeability, and viability caused by the presence of Triton X-100 (TX100), a nonionic surfactant, were studied by scanning electrochemical microscopy (SECM).
Related Papers (5)
Present and Future of Surface-Enhanced Raman Scattering
Judith Langer,Dorleta Jimenez de Aberasturi,Javier Aizpurua,Ramon A. Alvarez-Puebla,Baptiste Auguié,Baptiste Auguié,Jeremy J. Baumberg,Guillermo C. Bazan,Steven E. J. Bell,Anja Boisen,Alexandre G. Brolo,Jaebum Choo,Dana Cialla-May,Dana Cialla-May,Volker Deckert,Volker Deckert,Laura Fabris,Karen Faulds,F. Javier García de Abajo,Royston Goodacre,Duncan Graham,Amanda J. Haes,Christy L. Haynes,Christian W. Huck,Tamitake Itoh,Mikael Käll,Janina Kneipp,Nicholas A. Kotov,Hua Kuang,Eric C. Le Ru,Eric C. Le Ru,Hiang Kwee Lee,Jian-Feng Li,Xing Yi Ling,Stefan A. Maier,Thomas G. Mayerhöfer,Thomas G. Mayerhöfer,Martin Moskovits,Kei Murakoshi,Jwa-Min Nam,Shuming Nie,Yukihiro Ozaki,Isabel Pastoriza-Santos,Jorge Pérez-Juste,Juergen Popp,Juergen Popp,Annemarie Pucci,Stephanie Reich,Bin Ren,George C. Schatz,Timur Shegai,Sebastian Schlücker,Li-Lin Tay,K. George Thomas,Zhong-Qun Tian,Richard P. Van Duyne,Tuan Vo-Dinh,Yue Wang,Katherine A. Willets,Chuanlai Xu,Hongxing Xu,Yikai Xu,Yuko S. Yamamoto,Bing Zhao,Luis M. Liz-Marzán +64 more