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Open AccessJournal ArticleDOI

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

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TLDR
The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs.
Abstract
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.

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Citations
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Journal ArticleDOI

Autism Then and Now: Society and Science

TL;DR: Neymotin et al. as mentioned in this paper examined how we may view changes in the development and history of autism through a broader lens that incorporates the often ignored bi-directional interaction between science and cultural attitudes, and what this may imply for future research and treatments.
Dissertation

Development and evaluation of a questionnaire for feeding problems and gastrointestinal symptoms in children with Autism Spectrum Disorders and the impact of these problems on family life

TL;DR: The Brief structured questionnaire for the Early identification of Feeding problems and GI symptoms in primary school children with ASD (BEFGASD) is developed, the first questionnaire developed for use by community professionals and its psychometric properties are evaluated.
Book ChapterDOI

Autism and Medical Comorbidities

TL;DR: Inborn errors of metabolism should not typically be considered a comorbidity in ASD, but should not be neglected as a possible etiology of ASD in some very rare situations of syndromic autism with associated features.
Book ChapterDOI

Interdisciplinary Treatment for Pediatric Elimination Disorders

TL;DR: Biological and psychobehavioral underpinnings of elimination disorders will be addressed in this chapter and gold standard interdisciplinary treatment of elimination Disorders will be discussed and the evidence for this approach reviewed.
Journal ArticleDOI

Evaluation of Chronic Constipation in Children With Autism Spectrum Disorder

Ewelina Szpak
TL;DR: The authors found that chronic constipation is associated with a higher rate of abnormal colonic motor activity in ASD children than in non-ASD children, and that the risk for abnormal motility increased 11% for every 1-year increase in duration of constipation.
References
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Journal ArticleDOI

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Journal ArticleDOI

Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children

TL;DR: In this paper, the authors investigated a consecutive series of children with chronic enterocolitis and regressive developmental disorder, and identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.
Journal ArticleDOI

Neuroglial activation and neuroinflammation in the brain of patients with autism

TL;DR: It is indicated that innate neuroimmune reactions play a pathogenic role in an undefined proportion of autistic patients, suggesting that future therapies might involve modifying neuroglial responses in the brain.
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