Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report
Timothy Buie,Daniel B. Campbell,George J. Fuchs,Glenn T. Furuta,Glenn T. Furuta,Joseph Levy,Judy VandeWater,Agnes H. Whitaker,Dan Atkins,Dan Atkins,Margaret L. Bauman,Arthur L. Beaudet,Edward G. Carr,Michael D. Gershon,Susan L. Hyman,Pipop Jirapinyo,Harumi Jyonouchi,Koorosh Kooros,Rafail I. Kushak,Pat Levitt,Susan E. Levy,Jeffery D. Lewis,Katherine F. Murray,Marvin R. Natowicz,Aderbal Sabra,Barry K. Wershil,Sharon C. Weston,Lonnie K. Zeltzer,Harland S. Winter +28 more
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The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs.Abstract:
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.read more
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Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
Elaine Y. Hsiao,Sara Mcbride,Sophia Hsien,Gil Sharon,Embriette R. Hyde,Tyler McCue,Julian A. Codelli,Janet Chow,Sarah E. Reisman,Joseph F. Petrosino,Paul H. Patterson,Sarkis K. Mazmanian +11 more
TL;DR: A gut-microbiome-brain connection in a mouse model of ASD is supported and a potential probiotic therapy for GI and particular behavioral symptoms in human neurodevelopmental disorders is identified.
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TL;DR: In this article, the Gastroesophageal reflux (GER) is defined as passage of gastric contents into the esophagus, and GER disease (GERD) defined as symptoms or complications of GER, are common pediatric problems encountered by both primary and specialty medical providers.
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Positive Behavior Support for People with Developmental Disabilities: A Research Synthesis
Edward G. Carr,Robert H. Horner,Ann P. Turnbull,Janet Marquis,Darlene Magito McLaughlin,Michelle L. McAtee,Christopher E. Smith,Kaarin Anderson Ryan,Michael B. Ruef,Ajit Doolabh,David Braddock +10 more
TL;DR: In this article, the authors present a review of the published literature on positive behavior interventions and use this database to provide four main content areas for research: demographics, assessment practices, intervention strategies, and outcomes.
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Food Protein-Induced Enterocolitis Syndrome Caused by Solid Food Proteins
TL;DR: Cereals, vegetables, and poultry meats, typically regarded as of low allergenic potential, must be considered in the evaluation of FPIES, particularly in infants previously diagnosed with FPIES to cow's milk or soy, and as an initial cause in patients who have been exclusively breastfed.
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No evidence for a new variant of measles-mumps-rubella-induced autism.
Eric Fombonne,Suniti Chakrabarti +1 more
TL;DR: MMR immunization was not associated with a shift toward an earlier age for first parental concerns and is not suggestive of an increased frequency of this form of pervasive developmental disorder in samples of children who are immunized with MMR.