Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report
Timothy Buie,Daniel B. Campbell,George J. Fuchs,Glenn T. Furuta,Glenn T. Furuta,Joseph Levy,Judy VandeWater,Agnes H. Whitaker,Dan Atkins,Dan Atkins,Margaret L. Bauman,Arthur L. Beaudet,Edward G. Carr,Michael D. Gershon,Susan L. Hyman,Pipop Jirapinyo,Harumi Jyonouchi,Koorosh Kooros,Rafail I. Kushak,Pat Levitt,Susan E. Levy,Jeffery D. Lewis,Katherine F. Murray,Marvin R. Natowicz,Aderbal Sabra,Barry K. Wershil,Sharon C. Weston,Lonnie K. Zeltzer,Harland S. Winter +28 more
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TLDR
The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs.Abstract:
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care providers should be aware that problem behavior in patients with ASDs may be the primary or sole symptom of the underlying medical condition, including some gastrointestinal disorders. For these patients, integration of behavioral and medical care may be most beneficial. Priorities for future research are identified to advance our understanding and management of gastrointestinal disorders in persons with ASDs.read more
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Dietary Supplementation in Children with Autism Spectrum Disorders: Common, Insufficient, and Excessive
Patricia A. Stewart,Susan L. Hyman,Brianne Schmidt,Eric A. Macklin,Ann Reynolds,Cynthia Johnson,S. Jill James,Patricia Manning-Courtney +7 more
TL;DR: Few children with ASD need most of the micronutrients they are commonly given as supplements, which often leads to excess intake, and careful attention should be given to adequacy of vitamin D and calcium intake.
Journal ArticleDOI
Psychophysiological Associations with Gastrointestinal Symptomatology in Autism Spectrum Disorder.
Bradley J. Ferguson,Sarah Marler,Lily L. Altstein,Evon Batey Lee,Jill Akers,Kristin Sohl,Aaron McLaughlin,Kaitlyn Hartnett,Briana Kille,Micah O. Mazurek,Eric A. Macklin,Erin McDonnell,Mariah Barstow,Margaret L. Bauman,Kara Gross Margolis,Jeremy Veenstra-VanderWeele,David Q. Beversdorf +16 more
TL;DR: It is suggested that autonomic function and gastrointestinal problems are intertwined in children with ASD; although it is not possible to assess causality in this data set.
Journal ArticleDOI
Utilization Patterns of Conventional and Complementary/Alternative Treatments in Children with Autism Spectrum Disorders and Developmental Disabilities in a Population-Based Study
TL;DR: Use of CAM is common in families of young children with neurodevelopmental disorders, and it is predicted by higher parental education and non-Hispanic ethnicity but not developmental characteristics, and further research should address how health care providers can support families in making decisions about CAM use.
Journal ArticleDOI
Brief Report: “Allergic Symptoms” in Children with Autism Spectrum Disorders. More than Meets the Eye?
Asimenia Angelidou,Asimenia Angelidou,Konstantinos-Dionysios Alysandratos,Konstantinos-Dionysios Alysandratos,Shahrzad Asadi,Bodi Zhang,Konstantinos Francis,Magdalini Vasiadi,Magdalini Vasiadi,Dimitrios Kalogeromitros,Theoharis C. Theoharides +10 more
TL;DR: It is speculated that mast cell activation by allergic, infectious, environmental and stress-related triggers, especially perinatally, would release pro-inflammatory and neurotoxic molecules that could disrupt the gut–blood–brain barriers, thus contributing to brain inflammation and ASD pathogenesis.
Journal ArticleDOI
Behavioral Phenotype of ASD Preschoolers with Gastrointestinal Symptoms or Food Selectivity
Margherita Prosperi,Elisa Santocchi,Giulia Balboni,Antonio Narzisi,Margherita Bozza,Francesca Fulceri,Fabio Apicella,Roberta Igliozzi,Angela Cosenza,Raffaella Tancredi,Sara Calderoni,Filippo Muratori +11 more
TL;DR: The need for early identification of GI disturbances and FS in children with ASD in order to design tailored intervention for these symptoms frequently associated to challenging behaviours in ASD is indicated.
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