Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline
Michael F. Holick,Neil Binkley,Heike A. Bischoff-Ferrari,Catherine M. Gordon,David A. Hanley,Robert P. Heaney,M. Hassan Murad,Connie M. Weaver +7 more
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TLDR
Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances.Abstract:
Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. Participants: The Task Force was composed of a Chair, six additional experts, and a methodologist. The Task Force received no corporate funding or remuneration. Consensus Process: Consensus was guided by systematic reviews of evidence and discussions during several conference calls and e-mail communications. The draft prepared by the Task Force was reviewed successively by The Endocrine Society's Clinical Guidelines Subcommittee, Clinical Affairs Core Committee, and cosponsoring associations, and it was posted on The Endocrine Society web site for member review. At each stage of review, the Task Force received written comments and incorporated needed changes. Conclusions: Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recomme...read more
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Maternal Vitamin D Deficiency in Early Pregnancy Is Not Associated with Gestational Diabetes Mellitus Development or Pregnancy Outcomes in Korean Pregnant Women in a Prospective Study
Sunmin Park,Hyun-Koo Yoon,Hyun-Mee Ryu,You Jung Han,Si Won Lee,Bo-Kyung Park,Soyoung Park,Chang Hoon Yim,Sunghoon Kim +8 more
TL;DR: Neither GDM prevalence nor fetal growth during pregnancy is associated with vitamin D deficiency at the first trimester in Korean women, and pregnancy outcomes were independent of maternal serum 25-OH-D levels during the first, second and third trimester of pregnancy.
Journal ArticleDOI
Total 25-hydroxyvitamin D levels predict fracture risk: results from the 15-year follow-up of the Japanese Population-based Osteoporosis (JPOS) Cohort Study
Junko Tamaki,Masayuki Iki,Yuho Sato,Etsuko Kajita,Harumi Nishino,Takashi Akiba,Toshio Matsumoto,Sadanobu Kagamimori +7 more
TL;DR: Low 25(OH)D levels, especially <20 ng/mL, were associated with elevated fracture risks in Japanese women and remained significant in 10 and 15 years after adjusting for age and bone mineral density.
Journal ArticleDOI
Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis
Sebastião Cezar Radominski,Wanderley Marques Bernardo,Ana Patrícia de Paula,Ben-Hur Albergaria,Caio Moreira,César Eduardo Fernandes,Charlles Heldan de Moura Castro,Cristiano Augusto de Freitas Zerbini,Diogo Souza Domiciano,Laura Maria Carvalho de Mendonça,Luciano de Melo Pompei,Mailze Campos Bezerra,Marco Antonio Rocha Loures,Maria Celeste Osório Wender,Marise Lazaretti-Castro,Rosa Maria Rodrigues Pereira,Sergio Setsuo Maeda,Vera Lúcia Szejnfeld,Victoria Zeghbi Cochenski Borba +18 more
TL;DR: The Osteoporosis and Osteometabolic Diseases Committee of the Brazilian Society of Rheumatology, in conjunction with the Brazilian Medical Association and other Societies, has developed this update of the guidelines for the treatment of postmenopausal osteoporotic disease according to the best scientific evidence available.
Journal ArticleDOI
Prevalence and Determinants of Suboptimal Vitamin D Levels in a Multiethnic Asian Population.
Ryan Eyn Kidd Man,Ling-Jun Li,Ching-Yu Cheng,Tien Yin Wong,Ecosse L. Lamoureux,Charumathi Sabanayagam +5 more
TL;DR: Targeted interventions and stricter reinforcements of existing guidelines for vitamin D supplementation are needed for groups at risk of vitamin D insufficiency/deficiency.
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Effect of isolated vitamin D supplementation on the rate of falls and postural balance in postmenopausal women fallers: a randomized, double-blind, placebo-controlled trial.
Luciana Mendes Cangussu,Jorge Nahas-Neto,Claudio Lera Orsatti,Priscila Ferreira Poloni,Eneida Boteon Schmitt,Benedito de Sousa Almeida-Filho,Eliana Aguiar Petri Nahás +6 more
TL;DR: In Brazilian postmenopausal women fallers, isolated vitamin D supplementation for 9 months resulted in a lower incidence of falls and improvement in postural balance.
References
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Journal ArticleDOI
Vitamin D Deficiency
TL;DR: The role of vitamin D in skeletal and nonskeletal health is considered and strategies for the prevention and treatment ofitamin D deficiency are suggested.
Journal ArticleDOI
Grading quality of evidence and strength of recommendations.
David C. Atkins,Dana Best,Peter A. Briss,Martin P Eccles,Yngve Falck-Ytter,Signe Flottorp,Gordon H. Guyatt,Robin Harbour,Margaret C Haugh,David Henry,Suzanne Hill,Roman Jaeschke,Gillian Leng,Alessandro Liberati,Nicola Magrini,James Mason,Philippa Middleton,Jacek Mrukowicz,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Tessa Tan-Torres Edejer,H. Varonen,Gunn Elisabeth Vist,John W Williams,Stephanie Zaza +26 more
TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
Book
Vitamin D
TL;DR: In what case do you like reading so much? What about the type of the vitamin d the calcium homeostatic steroid hormone book? The needs to read? Well, everybody has their own reason why should read some books as discussed by the authors.
Journal ArticleDOI
Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response
Philip T. Liu,Steffen Stenger,Huiying Li,Linda Wenzel,Belinda H. Tan,Stephan R. Krutzik,Maria Teresa Ochoa,Jürgen Schauber,Kent Wu,Christoph Meinken,Diane L. Kamen,Manfred Wagner,Robert Bals,Andreas Steinmeyer,Ulrich Zügel,Richard L. Gallo,David Eisenberg,Martin Hewison,Bruce W. Hollis,John S. Adams,Barry R. Bloom,Robert L. Modlin +21 more
TL;DR: The data support a link between TLRs and vitamin D–mediated innate immunity and suggest that differences in ability of human populations to produce vitamin D may contribute to susceptibility to microbial infection.
Book
Dietary Reference Intakes for Calcium and Vitamin D
TL;DR: The evidence supported a role for these nutrients in bone health but not in other health conditions, and there is emerging evidence that too much of these nutrients may be harmful.