Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline
Michael F. Holick,Neil Binkley,Heike A. Bischoff-Ferrari,Catherine M. Gordon,David A. Hanley,Robert P. Heaney,M. Hassan Murad,Connie M. Weaver +7 more
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TLDR
Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances.Abstract:
Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. Participants: The Task Force was composed of a Chair, six additional experts, and a methodologist. The Task Force received no corporate funding or remuneration. Consensus Process: Consensus was guided by systematic reviews of evidence and discussions during several conference calls and e-mail communications. The draft prepared by the Task Force was reviewed successively by The Endocrine Society's Clinical Guidelines Subcommittee, Clinical Affairs Core Committee, and cosponsoring associations, and it was posted on The Endocrine Society web site for member review. At each stage of review, the Task Force received written comments and incorporated needed changes. Conclusions: Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recomme...read more
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Clinical Practice Guidelines for the Perioperative Nutritional, Metabolic, and Nonsurgical Support of the Bariatric Surgery Patient—2013 Update: Cosponsored by American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic & Bariatric Surgery
Jeffrey I. Mechanick,Adrienne Youdim,Daniel B. Jones,W. Timothy Garvey,Daniel L. Hurley,M. Molly McMahon,Leslie J. Heinberg,Robert F. Kushner,Ted D. Adams,Scott A. Shikora,John Dixon,Stacy A. Brethauer +11 more
TL;DR: These updated guidelines reflect recent additions to the evidence base and include Examples of expanded topics in this update include: the roles of sleeve gastrectomy, bariatric surgery in patients with type‐2 diabetes,bariatric surgery for patients with mild obesity, copper deficiency, informed consent, and behavioral issues.
Journal ArticleDOI
Evidence that Vitamin D Supplementation Could Reduce Risk of Influenza and COVID-19 Infections and Deaths.
William B. Grant,Henry Lahore,Sharon L. McDonnell,Carole A. Baggerly,Christine French,Jennifer L. Aliano,Harjit Pal Bhattoa +6 more
TL;DR: Evidence supporting the role of vitamin D in reducing risk of COVID-19 includes that the outbreak occurred in winter, a time when 25-hydroxyvitamin D concentrations are lowest; that the number of cases in the Southern Hemisphere near the end of summer are low; that vitamin D deficiency has been found to contribute to acute respiratory distress syndrome; and that case-fatality rates increase with age and with chronic disease comorbidity.
Journal ArticleDOI
The role of vitamin D in reducing cancer risk and progression
TL;DR: Accumulating results from preclinical and some clinical studies strongly suggest that vitamin D deficiency increases the risk of developing cancer and that avoiding deficiency and adding vitamin D supplements might be an economical and safe way to reduce cancer incidence and improve cancer prognosis and outcome.
Journal ArticleDOI
Vitamin D for Health: A Global Perspective
TL;DR: There is potentially a great upside to increasing the vitamin D status of children and adults worldwide for improving musculoskeletal health and reducing the risk of chronic illnesses, including some cancers, autoimmune diseases, infectious diseases, type 2 diabetes mellitus, neurocognitive disorders and mortality.
Journal ArticleDOI
The IOC consensus statement: beyond the Female Athlete Triad—Relative Energy Deficiency in Sport (RED-S)
Margo Mountjoy,Jorunn Sundgot-Borgen,Louise M. Burke,Susan D. Carter,Naama Constantini,Constance M. Lebrun,Nanna L. Meyer,Roberta Sherman,Kathrin Steffen,Richard Budgett,Arne Ljungqvist +10 more
TL;DR: The IOC expert working group introduces a broader, more comprehensive term for the condition previously known as ‘Female Athlete Triad’, ‘Relative Energy Deficiency in Sport’ (RED-S), and recommends practical clinical models for the management of affected athletes.
References
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Nutritional rickets around the world: causes and future directions
TL;DR: Rickets exists along a spectrum ranging from isolated vitamin D deficiency to isolated calcium deficiency, and it is likely that relative deficiencies of calcium and vitamin D interact with genetic and/or environmental factors to stimulate the development of rickets.
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Reduced vitamin D in acute stroke.
Kenneth E. S. Poole,Nigel Loveridge,Peter J. Barker,David Halsall,Collette Rose,Jonathan Reeve,Elizabeth A. Warburton +6 more
TL;DR: In this paper, the authors compared the serum 25-dihydroxyvitamin D levels of 44 patients admitted to an acute stroke unit with first-ever stroke with results obtained by measuring 96 healthy ambulant elderly subjects every 2 months for 1 year.
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Vitamin D Deficiency in a Healthy Group of Mothers and Newborn Infants
Joyce M. Lee,Jessica Smith,Barbara L. Philipp,Tai C. Chen,Jeffrey S. Mathieu,Michael F. Holick +5 more
TL;DR: Maternal vitamin D deficiency may represent an important risk factor for the development of rickets in children and a positive correlation between maternal and infant plasma 25-hydroxyvitamin D concentrations is found.
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G.D. Schott,M.R. Wills +1 more
TL;DR: The muscle weakness that frequently accompanies osteomalacia and rickets may arise from a variety of causes, and identification of the metabolic disorder is important, since effective treatment is often possible.
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A case for clarity, consistency, and helpfulness: State-of-the-art clinical practice guidelines in endocrinology using the grading of recommendations, assessment, development, and evaluation system
Brian A. Swiglo,Mohammad Hassan Murad,Holger J. Schünemann,Regina Kunz,Robert A. Vigersky,Gordon H. Guyatt,Victor M. Montori +6 more
TL;DR: The components of the GRADE system were summarized and described, and the features of GRADE that help bring clarity and consistency to guideline documents, making them more helpful to practicing clinicians and their patients with endocrine disorders were discussed.