Evaluation, Treatment, and Prevention of Vitamin D Deficiency: an Endocrine Society Clinical Practice Guideline
Michael F. Holick,Neil Binkley,Heike A. Bischoff-Ferrari,Catherine M. Gordon,David A. Hanley,Robert P. Heaney,M. Hassan Murad,Connie M. Weaver +7 more
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TLDR
Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recommended supplementation at suggested daily intake and tolerable upper limit levels, depending on age and clinical circumstances.Abstract:
Objective: The objective was to provide guidelines to clinicians for the evaluation, treatment, and prevention of vitamin D deficiency with an emphasis on the care of patients who are at risk for deficiency. Participants: The Task Force was composed of a Chair, six additional experts, and a methodologist. The Task Force received no corporate funding or remuneration. Consensus Process: Consensus was guided by systematic reviews of evidence and discussions during several conference calls and e-mail communications. The draft prepared by the Task Force was reviewed successively by The Endocrine Society's Clinical Guidelines Subcommittee, Clinical Affairs Core Committee, and cosponsoring associations, and it was posted on The Endocrine Society web site for member review. At each stage of review, the Task Force received written comments and incorporated needed changes. Conclusions: Considering that vitamin D deficiency is very common in all age groups and that few foods contain vitamin D, the Task Force recomme...read more
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Vitamin D: An overview of vitamin D status and intake in Europe
A. Spiro,Judy Buttriss +1 more
TL;DR: In most European countries, there seems to be a shortfall in achieving current vitamin D recommendations, and an exception is Finland, where dietary survey data indicate that recent national policies that include fortification and supplementation have resulted in an increase in vitamin D intakes, but this may not be a suitable strategy for all European populations.
Journal ArticleDOI
Effects of vitamin D supplements on bone mineral density: a systematic review and meta-analysis
TL;DR: Continuing widespread use of vitamin D for osteoporosis prevention in community-dwelling adults without specific risk factors for vitamin D deficiency seems to be inappropriate.
Journal ArticleDOI
IOM committee members respond to Endocrine Society vitamin D guideline.
Clifford J. Rosen,Steven A. Abrams,John F. Aloia,Patsy M. Brannon,Steven K. Clinton,Ramon Durazo-Arvizu,J. Christopher Gallagher,Richard L. Gallo,Glenville Jones,Christopher S. Kovacs,JoAnn E. Manson,Susan T. Mayne,A. Catharine Ross,Sue A. Shapses,Christine L. Taylor +14 more
TL;DR: Members of the Institute of Medicine committee respond to aspects of The Endocrine Society guideline that are not well supported and in need of reconsideration on target serum 25-hydroxyvitamin D levels and the definition of vitamin D deficiency.
Journal ArticleDOI
Vitamin D supplementation for prevention of mortality in adults
Goran Bjelakovic,Lise Lotte Gluud,Dimitrinka Nikolova,Kate Whitfield,Jørn Wetterslev,R. G. Simonetti,Marija Bjelakovic,Christian Gluud +7 more
TL;DR: Assessment of the beneficial and harmful effects of vitamin D supplementation for prevention of mortality in healthy adults and adults in a stable phase of disease demonstrated that vitamin D could be associated with a dramatic increase or decrease in mortality.
Journal ArticleDOI
Global Consensus Recommendations on Prevention and Management of Nutritional Rickets
Craig F Munns,Nick Shaw,Mairead Kiely,Bonny Specker,Tom D. Thacher,Keiichi Ozono,Toshimi Michigami,Dov Tiosano,M Zulf Mughal,Outi Mäkitie,Lorna Ramos-Abad,Leanne M Ward,Linda A. DiMeglio,Navoda Atapattu,Hamilton Cassinelli,Christian Braegger,John M. Pettifor,Anju Seth,Hafsatu Wasagu Idris,Vijayalakshmi Bhatia,Junfen Fu,Gail R Goldberg,Lars Sävendahl,Rajesh Khadgawat,Paweł Płudowski,Jane Maddock,Elina Hyppönen,AO Oduwole,Emma Frew,Magda Aguiar,Ted Tulchinsky,Gary Butler,Wolfgang Högler +32 more
TL;DR: Rickets, osteomalacia, and vitamin D and calcium deficiencies are preventable global public health problems in infants, children, and adolescents and implementation of international rickets prevention programs, including supplementation and food fortification is urgently required.
References
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Journal ArticleDOI
Vitamin D Deficiency
TL;DR: The role of vitamin D in skeletal and nonskeletal health is considered and strategies for the prevention and treatment ofitamin D deficiency are suggested.
Journal ArticleDOI
Grading quality of evidence and strength of recommendations.
David C. Atkins,Dana Best,Peter A. Briss,Martin P Eccles,Yngve Falck-Ytter,Signe Flottorp,Gordon H. Guyatt,Robin Harbour,Margaret C Haugh,David Henry,Suzanne Hill,Roman Jaeschke,Gillian Leng,Alessandro Liberati,Nicola Magrini,James Mason,Philippa Middleton,Jacek Mrukowicz,Dianne L. O'Connell,Andrew D Oxman,Bob Phillips,Holger J. Schünemann,Tessa Tan-Torres Edejer,H. Varonen,Gunn Elisabeth Vist,John W Williams,Stephanie Zaza +26 more
TL;DR: A system for grading the quality of evidence and the strength of recommendations that can be applied across a wide range of interventions and contexts is developed, and a summary of the approach from the perspective of a guideline user is presented.
Book
Vitamin D
TL;DR: In what case do you like reading so much? What about the type of the vitamin d the calcium homeostatic steroid hormone book? The needs to read? Well, everybody has their own reason why should read some books as discussed by the authors.
Journal ArticleDOI
Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response
Philip T. Liu,Steffen Stenger,Huiying Li,Linda Wenzel,Belinda H. Tan,Stephan R. Krutzik,Maria Teresa Ochoa,Jürgen Schauber,Kent Wu,Christoph Meinken,Diane L. Kamen,Manfred Wagner,Robert Bals,Andreas Steinmeyer,Ulrich Zügel,Richard L. Gallo,David Eisenberg,Martin Hewison,Bruce W. Hollis,John S. Adams,Barry R. Bloom,Robert L. Modlin +21 more
TL;DR: The data support a link between TLRs and vitamin D–mediated innate immunity and suggest that differences in ability of human populations to produce vitamin D may contribute to susceptibility to microbial infection.
Book
Dietary Reference Intakes for Calcium and Vitamin D
TL;DR: The evidence supported a role for these nutrients in bone health but not in other health conditions, and there is emerging evidence that too much of these nutrients may be harmful.