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From 2000 to mid-2010: a fruitful decade for the synthesis of pyrazoles.
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This article is published in Chemical Reviews.The article was published on 2011-08-01. It has received 839 citations till now.read more
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Molecular enneanuclear CuII phosphates containing planar hexanuclear and trinuclear sub-units: syntheses, structures, and magnetism
Biswajit Santra,Pankaj Kalita,Shubhadeep Chandra,Shubhadeep Chandra,Debdeep Mandal,Vierandra Kumar,Ramakirushnan Surya Narayanan,Atanu Dey,Nicolas Chrysochos,Volker Huch,Sourav Biswas,Debajyoti Ghoshal,E. Carolina Sañudo,Biprajit Sarkar,Biprajit Sarkar,Carola Schulzke,Vadapalli Chandrasekhar,Vadapalli Chandrasekhar,Anukul Jana +18 more
TL;DR: Magnetic studies reveal a strong antiferromagnetic exchange between the Cu(ii) centres of the dinuclear units in the hexanuclear part and a strong spin frustration in the trinuclear part leading to a degenerate ground state.
Journal ArticleDOI
Recyclable ZnIn2S4 Microspheres for Photocatalytic Azolation of N-Heterocycles
Runhe Wang,Fanlin Zeng,Xiaolan Chen,Hu-Lin Zhu,Lingbo Qu,Xiangyun Huang,Shirley Shu-mei Tang,Yufen Zhao,Bin Yu +8 more
TL;DR: In this article , a series of zinc indium sulfide (ZnIn2S4) was synthesized by solvothermal methods in different solvents and showed the highest photocurrent density.
Journal ArticleDOI
Cascade and multicomponent synthesis of structurally diverse 2-(pyrazol-3-yl)pyridines and polysubstituted pyrazoles.
TL;DR: In these multicomponent reactions, complex molecules featuring three different heterocycles are assembled in a single step from commercial materials, enabling the fast generation of molecular diversity.
Journal ArticleDOI
Synthesis, spectroscopic (FT-IR and NMR), DFT and molecular docking studies of ethyl 1-(3-nitrophenyl)-5-phenyl-3-((4-(trifluoromethyl)phenyl)carbamoyl)-1H-pyrazole-4-carboxylate
Journal ArticleDOI
Thermodynamic vs. Kinetic Control in Synthesis of O-Donor 2,5-Substituted Furan and 3,5-Substituted Pyrazole from Heteropropargyl Precursor
Anton A. Muravev,A. S. Ovsyannikov,Gennady V. Konorov,Daut R. Islamov,Konstantin S. Usachev,Alexander S. Novikov,Svetlana E. Solovieva,Igor S. Antipin +7 more
TL;DR: In this article , Sonogashira cross-coupling conditions of 4-tert-butylphenyl propargyl ether with benzoyl chloride followed by tandem Michael addition/cyclocondensation with hydrazine into 3,5-disubstituted pyrazole were established through a variation of the catalyst loading, solvent polarity, excess of triethylamine, and time of reaction.
References
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Recent developments in isocyanide based multicomponent reactions in applied chemistry
Journal ArticleDOI
Modern Synthetic Methods for Copper‐Mediated C(aryl) ? O, C(aryl) ? N, and C(aryl) ? S Bond Formation
Steven V. Ley,Andrew Thomas +1 more
TL;DR: In this article, the authors highlight the recent developments in the copper-mediated (both stoichiometric and catalytic) reactions of aryl boronic acids as reaction partners in both O- and N-arylation.
Journal ArticleDOI
Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
T. D. Penning,John J. Talley,Bertenshaw,Jeffery S. Carter,P. W. Collins,Stephen H. Docter,Matthew J. Graneto,Len F. Lee,James W. Malecha,Julie M. Miyashiro,Roland S. Rogers,D. J. Rogier,Stella S. Yu,AndersonGD,E. G. Burton,J. N. Cogburn,Susan A. Gregory,Carol M. Koboldt,W E Perkins,Karen Seibert,A. W. Veenhuizen,Yan Y. Zhang,P. C. Isakson +22 more
TL;DR: 1i (4-[5-(4-methylphenyl)-3-(trifluoromethyl)- H-pyrazol-1-yl]benzenesulfonamide, SC-58635, celecoxib), which is currently in phase III clinical trials for the treatment of rheumatoid arthritis and osteoarthritis, is identified.
Journal ArticleDOI
Copper-mediated coupling reactions and their applications in natural products and designed biomolecules synthesis.
TL;DR: Using R-Hydroxy Stannanes as a Model for a Methylenation Reaction and Conclusions and Future Prospects are presented.
BookDOI
Synthetic applications of 1,3-dipolar cycloaddition chemistry toward heterocycles and natural products
Albert Padwa,William H. Pearson +1 more
TL;DR: In this paper, the authors present a list of the most important properties of Nitrones and Azomethine Ylides: Nitrones (Jason N. Martin and Raymond C. Jones), Nitronates (Scott E. Denmark and Jeromy J. Cottell), Azides (Chin-Kang Sha and A. K. Mohanakrishnan). Mesoionic Ring Systems (Gordon W. Gribble). Effect of External Reagents (Shuji Kanemasa). Asymmetric Reactions (Kurt Vesterager Gothe
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Synthesis and biological evaluation of the 1,5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benze nesulfonamide (SC-58635, celecoxib).
T. D. Penning,John J. Talley,Bertenshaw,Jeffery S. Carter,P. W. Collins,Stephen H. Docter,Matthew J. Graneto,Len F. Lee,James W. Malecha,Julie M. Miyashiro,Roland S. Rogers,D. J. Rogier,Stella S. Yu,AndersonGD,E. G. Burton,J. N. Cogburn,Susan A. Gregory,Carol M. Koboldt,W E Perkins,Karen Seibert,A. W. Veenhuizen,Yan Y. Zhang,P. C. Isakson +22 more