What contributions have the authors mentioned in the paper "Gastrointestinal problems in children with autism, developmental delays or typical development" ?

The authors also examined scores on five Aberrant Behavior Checklist ( ABC ) subscales comparing ASD children with high versus low frequency GI symptoms. Maladaptive behaviors correlate with GI problems, suggesting these comorbidities require attention.

What is the frequently reported food sensitivity or allergy for all diagnostic groups?

Descriptive analyses of parental responses to related open ended GI questions indicated the most frequently reported food sensitivity or allergy for all diagnostic groups was dairy/casein (14.6 % ASD, 6.6 % DD and 5.3 % TD).

What is the role of cell-mediated immunity in non-allergic food hypersensitivity?

Cell-mediated immunity plays a role in non-allergic food hypersensitivity and reactions take place several hours and even 1–2 days after the intake of the culprit (Jyonouchi et al. 2005).

What was the common GI symptom in children with TD?

Children with ASD were at least three times more likely to experience frequent GI symptoms than children with TD: abdominal pain, pain on stooling, constipation, gaseousness/bloating, diarrhea, sensitivity to foods, as well as vomiting and difficulty swallowing, which were very rare in TD controls.

What is the common food allergy for children with ASD?

For children with ASD, other commonly reported food allergies or sensitivities included the grains category (including gluten, 7.8 %) and nuts/soy (7 %).

How many cases of GI problems were reported in the study?

Another recent case–control population based study (n = 121 cases, n = 242 controls) in Olmstead County, Minnesota, where >95 % of medical care is provided by Olmstead Medical Center/Mayo Clinic, medical charts provided data for GI symptoms from birth to 21 years of age (Ibrahim et al. 2009).

What is the role of CMP in GI symptoms in children with autism?

At least one group of researchers has demonstrated that in children with ASD, it is nonallergic food hypersensitivity to cow’s milk protein (CMP), and not casein that plays a role in GI symptoms observed in some children with ASD (Jyonouchi et al. 2005).

What is the link between GI dysfunction and autism?

It is plausible that a chronic GI symptom, which can cause pain, discomfortand anxiety, could contribute to increased irritability and social withdrawal, particularly in someone with deficits in social and communicative skills.

What is the role of diet in GI problems in children with autism?

Diarrhea and constipation arefrequently cited in studies examining GI symptoms in children with autism, but to date, only one has examined the role of diet in GI problems (Gorrindo et al. 2012).

What is the way to treat GI symptoms in children with autism?

Appropriate treatment of GI symptoms may help alleviate at least some problematic behaviors and improve the quality of life in children with ASD along with their families.

What is the common GI symptom in children with ASD?

In children with ASD, four out of five behavior subscales (irritability, social withdrawal, stereotypy and hyperactivity) on the ABC were significantly higher in children with frequent occurrences of abdominal pain, gaseousness, diarrhea and constipation as compared to children with no frequent GI symptoms (Table 5).

What is the common GI symptom in children with DD?

Vomiting is a relatively infrequent GI symptom reported, and ASD without DD had higher occurrence than ASD with DD (p = 0.02; Table 1S).

How many times did children with DD experience frequent sensitivity to foods?

children with DD were at least three times more likely than children with TD to experience frequent sensitivity to foods, pain on stooling, diarrhea, constipation, as well as difficulty swallowing and vomiting.

(Open Access) Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development. (2014) | Virginia Chaidez

Q: What are the future works mentioned in the paper "Gastrointestinal problems in children with autism, developmental delays or typical development" ?

To investigate whether diet plays a role in the prevalence of GI problems, future studies should attempt to measure diet quality and quantity of key macronutrients with special attention to fiber, water, and fats, in addition to micronutrients such as iron, zinc, vitamin A, vitamin B12, folate and iodine. Future work examining GI problems in children with ASD and DD should standardize definitions for GI symptoms and more studies need to incorporate measures of dietary intake and nutritional status. Investigating the dual role of neurotransmitters active in both the gut and the brain in future studies may advance their understanding of underlying mechanisms important to both. One small study suggests that children with ASDs may have inadequate intakes of fiber, calcium, iron, vitamin E and vitamin D ( Herndon et al. 2009 ).

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Nutrition and Health Sciences -- Faculty

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Nutrition and Health Sciences, Department of

2014

Gastrointestinal Problems in Children with Autism, Developmental Gastrointestinal Problems in Children with Autism, Developmental

Delays or Typical Development Delays or Typical Development

Virginia Chaidez

University of Nebraska - Lincoln

, vchaidez2@unl.edu

Robin L. Hansen

University of California, Davis School of Medicine

, rlhansen@ucdavis.edu

Irva Hertz-Picciotto

University of California, Davis

, iher@ucdavis.edu

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Gastrointestinal Problems in Children

with Autism, Developmental Delays

or Typical Development

Virginia Chaidez,

Robin L. Hansen,

2,3

& Irva Hertz-Picciotto

3,4















Correspondence:vchaidez2@unl.edu

Abstract

 

-







-











digitalcommons.unl.edu

Published in Journal of Autism and Developmental Disorders







 J Autism Dev Disord 







Keywords: -



Introduction

-

-











-



studies including, but not limited to: variations in the criteria used to

-

-









-











-

-





-









 J Autism Dev Disord 

-















-

-

-



-

















-







-













-





-







 J Autism Dev Disord 

Methods

Study Design and Sample





-















-

-

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

-

and 



Gastrointestinal Problems in Children with Autism, Developmental Delays or Typical Development.

Figures

Citations

Autism spectrum disorder.

Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study

The Changing Epidemiology of Autism Spectrum Disorders

Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice

Identification, Evaluation, and Management of Children With Autism Spectrum Disorder.

References

Mullen Scales of Early Learning

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism.

Frequency of gastrointestinal symptoms in children with autistic spectrum disorders and association with family history of autoimmune disease.

Incidence of gastrointestinal symptoms in children with autism: a population-based study.

Related Papers (5)

Gastrointestinal flora and gastrointestinal status in children with autism--comparisons to typical children and correlation with autism severity.

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs: A Consensus Report

Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders

Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children

Reduced Incidence of Prevotella and Other Fermenters in Intestinal Microflora of Autistic Children

Frequently Asked Questions (14)

Q1. What contributions have the authors mentioned in the paper "Gastrointestinal problems in children with autism, developmental delays or typical development" ?

Q2. What are the future works mentioned in the paper "Gastrointestinal problems in children with autism, developmental delays or typical development" ?

Q3. What is the frequently reported food sensitivity or allergy for all diagnostic groups?

Q4. What is the role of cell-mediated immunity in non-allergic food hypersensitivity?

Q5. What was the common GI symptom in children with TD?

Q6. What is the common food allergy for children with ASD?

Q7. How many cases of GI problems were reported in the study?

Q8. What is the role of CMP in GI symptoms in children with autism?

Q9. What is the link between GI dysfunction and autism?

Q10. What is the role of diet in GI problems in children with autism?

Q11. What is the way to treat GI symptoms in children with autism?

Q12. What is the common GI symptom in children with ASD?

Q13. What is the common GI symptom in children with DD?

Q14. How many times did children with DD experience frequent sensitivity to foods?