Journal ArticleDOI
Genomic sequences of bacteriophages HK97 and HK022: pervasive genetic mosaicism in the lambdoid bacteriophages.
Robert J Juhala,Michael E. Ford,Robert L. Duda,Anthony Youlton,Graham F. Hatfull,Roger W. Hendrix +5 more
TLDR
The complete genome DNA sequences of HK97 and HK022, double-stranded DNA bacteriophages of Escherichia coli and members of the lambdoid or lambda-like group of phages, are reported and a new class of genetic elements, the morons, are identified, which consist of a protein-coding region flanked by aPutative delta 70 promoter and a putative factor-independent transcription terminator.About:
This article is published in Journal of Molecular Biology.The article was published on 2000-05-26. It has received 463 citations till now. The article focuses on the topics: Comparative genomics & Genome.read more
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Phages and the Evolution of Bacterial Pathogens: from Genomic Rearrangements to Lysogenic Conversion
TL;DR: The current review presents the available genomics and biological data on prophages from bacterial pathogens in an evolutionary framework to demonstrate that the chromosomes from bacteria and their viruses (bacteriophages) are coevolving.
Journal ArticleDOI
Prophages and bacterial genomics: what have we learned so far?
TL;DR: In this paper, the evolution of integrated virus genomes (prophages) is analyzed using nucleotide sequence analysis, and it is shown that some prophages can lie in residence for very long times, perhaps millions of years, and that recombination events have occurred between related Prophages that reside at different locations in a bacterium's genome.
Journal ArticleDOI
Genome sequence of the dissimilatory metal ion-reducing bacterium Shewanella oneidensis.
John F. Heidelberg,Ian T. Paulsen,Karen E. Nelson,Eric Gaidos,Eric Gaidos,William C. Nelson,Timothy D. Read,Jonathan A. Eisen,Rekha Seshadri,Naomi L. Ward,Barbara A. Methé,Rebecca A. Clayton,Terry E. Meyer,A. I. Tsapin,James Scott,Maureen J. Beanan,Lauren M. Brinkac,Sean C. Daugherty,Robert T. DeBoy,Robert J. Dodson,A. Scott Durkin,Daniel H. Haft,James F. Kolonay,Ramana Madupu,Jeremy Peterson,Lowell Umayam,Owen White,Alex M. Wolf,Jessica Vamathevan,Janice Weidman,Marjorie Impraim,K. Lee,Kristy Berry,Chris Lee,Jacob L. Mueller,Hoda Khouri,John Gill,T. Utterback,Lisa McDonald,Tamara Feldblyum,Hamilton O. Smith,J. Craig Venter,Kenneth H. Nealson,Kenneth H. Nealson,Claire M. Fraser +44 more
TL;DR: This genome sequence represents a critical step in the elucidation of the pathways for reduction (and bioremediation) of pollutants such as uranium (U) and chromium (Cr), and offers a starting point for defining this organism's complex electron transport systems and metal ion–reducing capabilities.
Approved for Public Release; Distribution is Unlimited
TL;DR: LaRonde as mentioned in this paper analyzes the conflict in Xinjiang and concludes that the Chinese continue to defeat the separatist movement through a strategy that counters Mao's seven fundamentals of revolutionary warfare, concluding that Mao, as well as the communist leaders who followed him, was also successful at waging protracted counterinsurgency.
Journal ArticleDOI
Here a virus, there a virus, everywhere the same virus?
Mya Breitbart,Forest Rohwer +1 more
TL;DR: These findings suggest that viral diversity could be high on a local scale but relatively limited globally, and by moving between environments, viruses can facilitate horizontal gene transfer.
References
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Journal ArticleDOI
DNA sequencing with chain-terminating inhibitors
TL;DR: A new method for determining nucleotide sequences in DNA is described, which makes use of the 2',3'-dideoxy and arabinon nucleoside analogues of the normal deoxynucleoside triphosphates, which act as specific chain-terminating inhibitors of DNA polymerase.
Journal ArticleDOI
Virioplankton: viruses in aquatic ecosystems
KE Wommack,Rita R. Colwell +1 more
TL;DR: Novel applications of molecular genetic techniques have provided good evidence that viral infection can significantly influence the composition and diversity of aquatic microbial communities, supporting the hypothesis that viruses play a significant role in microbial food webs.
Journal ArticleDOI
High abundance of viruses found in aquatic environments.
TL;DR: Using a new method for quantitative enumeration, up to 2.5 x IO8 virus particles per millilitre in natural waters indicate that virus infection may be an important factor in the ecological control of planktonic micro-organisms.
Journal ArticleDOI
Nucleotide Sequence of Bacteriophage Lambda DNA
TL;DR: The distribution of other rare codons in the genes of the left arm suggests that they may have a controlling function on the relative amounts of the proteins produced, and the genome is fairly compact with comparatively little non-coding DNA.
Journal ArticleDOI
Amelioration of Bacterial Genomes: Rates of Change and Exchange
TL;DR: Estimates of amelioration times indicate that the entire Escherichia coli chromosome contains more than 600 kb of horizontally transferred, protein-coding DNA, which predicts that the E. coli and Salmonella enterica lineages have each gained and lost more than 3 megabases of novel DNA since their divergence.
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Origins of Highly Mosaic Mycobacteriophage Genomes
Marisa L. Pedulla,Michael E. Ford,Jennifer M. Houtz,Tharun Karthikeyan,Curtis Wadsworth,John A. Lewis,Debbie Jacobs-Sera,Jacob Falbo,Joseph Gross,Nicholas R. Pannunzio,William J. Brucker,Vanaja Kumar,Jayasankar Kandasamy,Lauren Keenan,Svetoslav Bardarov,Jordan Kriakov,Jeffrey G. Lawrence,William R. Jacobs,Roger W. Hendrix,Graham F. Hatfull +19 more