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Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Lung Disease 2017 Report: GOLD Executive Summary.

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TLDR
The assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation, and the importance of comorbid conditions in managing COPD is reviewed.
Abstract
This Executive Summary of the Global Strategy for the Diagnosis, Management, and Prevention of COPD (GOLD) 2017 Report focuses primarily on the revised and novel parts of the document. The most significant changes include: 1) the assessment of chronic obstructive pulmonary disease has been refined to separate the spirometric assessment from symptom evaluation. ABCD groups are now proposed to be derived exclusively from patient symptoms and their history of exacerbations; 2) for each of the groups A to D, escalation strategies for pharmacological treatments are proposed; 3) the concept of de-escalation of therapy is introduced in the treatment assessment scheme; 4) nonpharmacologic therapies are comprehensively presented and; 5) the importance of comorbid conditions in managing COPD is reviewed.

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Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Joan B. Soriano, +132 more
TL;DR: The GBD study provides annual updates on estimates of deaths, prevalence, and disability-adjusted life years (DALYs), a summary measure of fatal and non-fatal disease outcomes, for over 300 diseases and injuries, for 188 countries from 1990 to the most recent year.
Journal ArticleDOI

Exacerbations of COPD

TL;DR: The importance of preventing exacerbations of COPD is highlighted, including choice of pharmacotherapy, including bronchodilators, inhaled corticosteroids, phosphodiesterase-4 inhibitors, long-term antibiotics and mucolytics.
References
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Journal ArticleDOI

Increasing implementation and delivery of pulmonary rehabilitation: key messages from the new ATS/ERS policy statement.

TL;DR: The goal of the New Policy Statement is to expand provision of pulmonary rehabilitation to suitable patients worldwide to improve the quality of life for patients with pulmonary disease.
Journal ArticleDOI

Value of theophylline treatment in patients handicapped by chronic obstructive lung disease.

TL;DR: Theophylline treatment with sustained steady state concentrations about 17 mg/l provides worthwhile objective and subjective further benefits for patients handicapped by chronic obstructive lung disease when it is added to bronchodilators and corticosteroids.
Journal ArticleDOI

Chronic non-invasive ventilation in COPD: where do we stand?

TL;DR: Het RESCUE onderzoek was een nationale studie waar 48 ziekenhuizen aan hebben mee gewerkt met in totaal 201 patienten die voor de periode van een jaar zijn gevolgd.
Journal ArticleDOI

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

TL;DR: Tadalafil does not improve exercise capacity or quality of life despite exerting pulmonary vasodilation, and 19 of 60 patients in the treatment group had dyspepsia, with four of 19 patients needing a proton-pump inhibitor.
Journal ArticleDOI

Cardiac dysfunction during exacerbations of chronic obstructive pulmonary disease

TL;DR: Evidence about cardiac involvement in exacerbations of COPD is presented, and diagnostic challenges and treatment opportunities are discussed.
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