Journal ArticleDOI
Human fetal liver fatty acid binding proteins. Role on glucose-6-phosphate dehydrogenase activity.
TLDR
F fetal liver FABPs play a regulatory role in critical aspects of cellular physiology during human embryogenesis and protect glucose-6-phosphate dehydrogenase from the feed-back inhibition exerted by added palmitoyl-CoA and oleate.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1989-04-03. It has received 16 citations till now. The article focuses on the topics: Fatty acid synthesis & Fatty acid-binding protein.read more
Citations
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Journal ArticleDOI
Structural and functional features of different types of cytoplasmic fatty acid-binding proteins
TL;DR: Article de synthese sur les donnees recentes de caracteristiques structurales et physicochimiques de divers types of proteines de liaison aux acides gras, avec la signification physiologique de ces diversites.
Journal ArticleDOI
Functions of fatty acid binding proteins.
TL;DR: A considerable body of indirect evidence is provided supporting a broad role for the FABP in the intracellular transport and metabolism of long-chain fatty acids and the existence of structure- and tissue-specific specialization of function among different members of the F ABP gene family.
Journal ArticleDOI
Fatty acid binding protein isoforms: structure and function
TL;DR: Which FABPs form biochemically defined or true isoforms versus FABP that form additional forms, operationally defined as isoforms, is critically evaluated.
Journal ArticleDOI
Acyl-CoA binding proteins: Multiplicity and function
Ruanna E. Gossett,Andrey Frolov,John B. Roths,W. David Behnke,Ann B. Kier,Friedhelm Schroeder +5 more
TL;DR: The identity, nature, function, and pathobiology of these fascinating newly discovered long-chain fatty acyl-CoA binding proteins are explored.
Journal ArticleDOI
Isoforms of rat liver fatty acid binding protein differ in structure and affinity for fatty acids and fatty acyl CoAs.
TL;DR: Rat L-FABP isoforms differ markedly in both structure and ligand binding function, and displacement studies indicated that each isoform displayed distinct specificities for fatty acid/fatty acyl CoA chain length and unsaturation.
References
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Journal ArticleDOI
Large scale purification and structural characterization of squalene and sterol carrier protein.
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Utilization of long chain fatty acids by rat liver: studies of the role of fatty acid binding protein.
TL;DR: Although its possible role as a fatty acid "carrier" remains uncertain, FABP influences the activity of enzyme reactions in which fatty acid and fatty acid acyl CoA are substrates, is associated with large quantities of endogenous unsaturated fatty acids, and may be important in the utilization of fatty acids formed within the cell, de novo or by ester hydrolysis.
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Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications.
Lawrence Chan,Chik-Fong Wei,Wen-Hsiung Li,Chao-Yuh Yang,P. Ratner,Henry J. Pownall,Antonio M. Gotto,L. C. Smith +7 more
TL;DR: Primary structure predictions from the primary sequence of human and rat L-FABP reveal a region (residues 12-30) that might be the putative fatty acid binding domain of the two L-fABPs.
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Inhibition of rat liver acetyl coenzyme A carboxylase by long chain acyl coenzyme A and fatty acid. Modulation by fatty acid-binding protein.
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Deficiency of Hepatic Organic Anion-Binding Protein, Impaired Organic Anion Uptake by Liver and Physiologic Jaundice in Newborn Monkeys
TL;DR: It is suggested that relative deficiency of Y, the main acceptor protein, may be important in the etiology of "physiologic jaundice" in monkeys as well as other primates, including man.