Journal ArticleDOI
Human fetal liver fatty acid binding proteins. Role on glucose-6-phosphate dehydrogenase activity.
TLDR
F fetal liver FABPs play a regulatory role in critical aspects of cellular physiology during human embryogenesis and protect glucose-6-phosphate dehydrogenase from the feed-back inhibition exerted by added palmitoyl-CoA and oleate.About:
This article is published in Biochimica et Biophysica Acta.The article was published on 1989-04-03. It has received 16 citations till now. The article focuses on the topics: Fatty acid synthesis & Fatty acid-binding protein.read more
Citations
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Journal ArticleDOI
Structural and functional features of different types of cytoplasmic fatty acid-binding proteins
TL;DR: Article de synthese sur les donnees recentes de caracteristiques structurales et physicochimiques de divers types of proteines de liaison aux acides gras, avec la signification physiologique de ces diversites.
Journal ArticleDOI
Functions of fatty acid binding proteins.
TL;DR: A considerable body of indirect evidence is provided supporting a broad role for the FABP in the intracellular transport and metabolism of long-chain fatty acids and the existence of structure- and tissue-specific specialization of function among different members of the F ABP gene family.
Journal ArticleDOI
Fatty acid binding protein isoforms: structure and function
TL;DR: Which FABPs form biochemically defined or true isoforms versus FABP that form additional forms, operationally defined as isoforms, is critically evaluated.
Journal ArticleDOI
Acyl-CoA binding proteins: Multiplicity and function
Ruanna E. Gossett,Andrey Frolov,John B. Roths,W. David Behnke,Ann B. Kier,Friedhelm Schroeder +5 more
TL;DR: The identity, nature, function, and pathobiology of these fascinating newly discovered long-chain fatty acyl-CoA binding proteins are explored.
Journal ArticleDOI
Isoforms of rat liver fatty acid binding protein differ in structure and affinity for fatty acids and fatty acyl CoAs.
TL;DR: Rat L-FABP isoforms differ markedly in both structure and ligand binding function, and displacement studies indicated that each isoform displayed distinct specificities for fatty acid/fatty acyl CoA chain length and unsaturation.
References
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Journal ArticleDOI
Binding of bile acids, oleic acid, and organic anions by rat and human hepatic Z protein.
Hajime Takikawa,Neil Kaplowitz +1 more
TL;DR: The role for Z protein in the intracellular binding of bile acids may be particularly important in human liver, as both rat and human Z protein exhibited similar binding affinities for bile acid, oleic acid, and organic anions.
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The role of fatty acid binding protein on the metabolism of fatty acids in isolated rat hepatocytes.
TL;DR: The results indicate that the cytosol fatty-acid-binding protein directs the metabolism of long chain fatty acids toward esterification as well as enhancing their cellular uptake.
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The metabolism of variously C14-labeled glucose in man and an estimation of the extent of glucose metabolism by the hexose monophosphate pathway.
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Glucose catabolism in fetal and adult heart.
TL;DR: The experiments reported here indicate that in fetal heart tissue, with a higher rate of protein synthesis than found in adult cardiac tissue, a higher RNA content and pentose cycle activity might be anticipated.
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Isolation and characterization of the fatty acid binding protein from human heart.
TL;DR: The data elaborated by us and others support the existence of a cardiac-type FABP that is distinct from the well-defined hepatic-type and gut-types FABPs, as well as immunological cross-reactivities showed a relationship between FABs from several mammalian heart tissues.