Journal ArticleDOI
IAGG Workshop : Health promotion program on prevention of late onset dementia
Sandrine Andrieu,Isabella Aboderin,Jean-Pierre Baeyens,John R. Beard,Athanase Benetos,Gilles Berrut,Michael Brainin,Heung Bong Cha,Liang Kung Chen,P. Du,B. Forette,Françoise Forette,Alain Franco,Laura Fratiglioni,Sophie Gillette-Guyonnet,Gabriel Gold,Fernando Gomez,R M Guimarães,Deborah Gustafson,Ara S. Khachaturian,José A. Luchsinger,Francesca Mangialasche,Hélène Mathiex-Fortunet,Jean-Pierre Michel,Edo Richard,Lon S. Schneider,Alina Solomon,Bruno Vellas +27 more
TLDR
Thirty world specialists coming from Europe, North America, Asia, South America, Africa and Australia, shared their experience on methods and results of large epidemiological interventions to reduce incidents of dementia or delay its on-set.Abstract:
IAGG, WHO, and SFGG organized a international workshop on Health promotion programs on prevention of late on-set dementia. Thirty world specialists coming from Europe, North America, Asia, South America, Africa and Australia, shared their experience on methods and results of large epidemiological interventions to reduce incidents of dementia or delay its on-set. Chaired by Laura FRATIGLIONI, an expert in Epidemiological studies on dementia issues, the workshop gave opportunity for discussions and controversies about the state-of-the-art. Based on different national and international trials (ADAPT, MAPT, FINGER, GUDIAGE, GEM etc) the questions remained opened for different aspects of methodology, the choice of domain or multi domain intervention, the choice and the definition of the target populations, the best age of candidates, the issues related to the discrepancy between late effects, and interventions' duration. We are please to publish in the Journal, the presentations presented to this workshop. These publications will complete previously task force published in the journal in the last two years on methodological issues for Alzheimer's trials including end point, biomarkers, and the experience of past therapeutic trials.read more
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Journal ArticleDOI
Towards a comprehensive public health response to population ageing
John R. Beard,David E. Bloom +1 more
TL;DR: Older people can be valuable economic, social, cultural, and familial resources, but are also likely to be associated with a shrinking workforce and higher demand for health care, social care, and social pensions.
Mapt study: a multidomain approach for preventing alzheimer’s disease: design and baseline data
Bruno Vellas,Isabelle Carrié,Sophie Gillette-Guyonnet,Jacques Touchon,Thierry Dantoine,J. F. Dartigues,M.-N. Cuffi,Serge Bordes,Yannick Gasnier,P. Robert,Lawrence Bories,Olivier Rouaud,Françoise Desclaux,Kristelle Sudres,Marc Bonnefoy,Alain Pesce,Carole Dufouil,Stéphane Lehéricy,Marie Chupin,Jean-François Mangin,Pierre Payoux,D. Adel,Philippe Legrand,D Catheline,C Kanony,M. Zaim,Laurent Molinier,Nadège Costa,J. Delrieu,Thierry Voisin,Catherine Faisant,Françoise Lala,Fati Nourhashemi,Yves Rolland,G. Abellan Van Kan,Charlotte Dupuy,Christelle Cantet,P Cestac,Sylvie Belleville,Sherry L. Willis,Matteo Cesari,M. Weiner,Maria Soto,Pierre-Jean Ousset,Sandrine Andrieu +44 more
TL;DR: The MAPT trial is presently the first largest and longest multidomain preventive trial relevant to cognitive decline in older adults with subjective memory complaints and is likely to be easily implemented within the general population.
Journal ArticleDOI
Dementia prevention: current epidemiological evidence and future perspective
Francesca Mangialasche,Francesca Mangialasche,Miia Kivipelto,Miia Kivipelto,Alina Solomon,Alina Solomon,Laura Fratiglioni +6 more
TL;DR: There is sufficient evidence that vascular risk factors significantly contribute to the expression and progression of cognitive decline but that active engagement in social, physical, and mentally stimulating activities may delay the onset of dementia, but these findings need to be confirmed by randomized controlled trials (RCTs).
Journal ArticleDOI
Validity of dementia and Alzheimer's disease diagnoses in Finnish national registers.
Alina Solomon,Alina Solomon,Tiia Ngandu,Tiia Ngandu,Hilkka Soininen,Merja Hallikainen,Miia Kivipelto,Tiina Laatikainen,Tiina Laatikainen +8 more
TL;DR: In this paper, the authors investigated dementia and Alzheimer disease (AD) diagnoses in three national registers in Finland: the Hospital Discharge Register (HDR), the Drug Reimbursement Register, and the Causes of Death Register (CDR).
References
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