Lifetime Incidence of CKD Stages 3-5 in the United States
Morgan E. Grams,Morgan E. Grams,Eric K.H. Chow,Dorry L. Segev,Dorry L. Segev,Josef Coresh,Josef Coresh +6 more
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TLDR
In the United States, the lifetime risk of developing CKD stage 3a+ is high, emphasizing the importance of primary prevention and effective therapy to reduce CKD-related morbidity and mortality.About:
This article is published in American Journal of Kidney Diseases.The article was published on 2013-08-01 and is currently open access. It has received 249 citations till now. The article focuses on the topics: End stage renal disease & Population.read more
Citations
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Journal ArticleDOI
Early chronic kidney disease: diagnosis, management and models of care
TL;DR: Which early CKD interventions are appropriate, the optimum time to provide clinical care, and the most suitable model of care to adopt are discussed.
Journal ArticleDOI
The case for early identification and intervention of chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference
Michael G. Shlipak,Michael G. Shlipak,Sri Lekha Tummalapalli,Sri Lekha Tummalapalli,L. Ebony Boulware,Morgan E. Grams,Morgan E. Grams,Joachim H. Ix,Joachim H. Ix,Vivekanand Jha,Vivekanand Jha,Vivekanand Jha,Andre Pascal Kengne,Andre Pascal Kengne,Magdalena Madero,Borislava Mihaylova,Borislava Mihaylova,Navdeep Tangri,Michael Cheung,Michel Jadoul,Wolfgang C. Winkelmayer,Sophia Zoungas,Georgi Abraham,Zanfina Ademi,Radica Z. Alicic,Ian H. de Boer,Raj Deo,Xiaoqiang Ding,Natalie Ebert,Kevin J. Fowler,Linda F. Fried,Ron T. Gansevoort,Guillermo Garcia-Garcia,Brenda R. Hemmelgarn,Jessica Lee Harding,Joanna Q. Hudson,Kunitoshi Iseki,Vasantha Jotwani,Leah S. Karliner,Andrew S. Levey,Adrian Liew,Peter J. Lin,Andrea O.Y. Luk,Verónica Martínez,Andrew E. Moran,Mai Nguyen,Gregorio T. Obrador,Donal O'Donoghue,Meda E. Pavkov,Jessie Pavlinac,Neil R. Powe,Jesse C. Seegmiller,Jenny I. Shen,Rukshana Shroff,Laura Sola,Maarten W. Taal,James Tattersall,Joseph A. Vassalotti,Matthew R. Weir,Ella Zomer +59 more
TL;DR: KDIGO held a controversies conference and a consensus emerged that CKD screening coupled with risk stratification and treatment should be implemented immediately in high-risk persons and that this should ideally occur in primary or community care settings with tailoring to the local context.
Journal ArticleDOI
Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort
Stephanie Titze,Matthias Schmid,Matthias Schmid,Anna Köttgen,Martin Busch,Jürgen Floege,Christoph Wanner,Florian Kronenberg,Kai-Uwe Eckardt,Prokosch Hu,Barbara Bärthlein,Andreas Beck,Thomas Ganslandt,Olaf Gefeller,Jan Köster,Martina Malzer,Georg Schlieper,Frank Eitner,Sabine Meisen,Katharina Kehl,Elfriede Arweiler,Elke Schaeffner,Seema Baid-Agrawal,Ralf Schindler,Silvia de Oliveira Hübner,Thomas Dienemann,Karl F. Hilgers,Ulla T. Schultheiß,Gerd Walz,Jan T. Kielstein,Johan M. Lorenzen,Hermann Haller,Claudia Sommerer,Martin Zeier,Katharina Paul,Gunter Wolf,Robert Hilge,Thomas Sitter,Vera Krane,Daniel Schmiedeke,Sebastian Toncar,Arif B. Ekici,André Reis,Lukas Forer,Sebastian Schönherr,Hansi Weissensteiner,Barbara Kollertits,Julia Raschenberger,Wolfram Gronwald,Helena U. Zacharias,Peter J. Oefner +50 more
TL;DR: Patients with moderate CKD under specialist care have a high disease burden and improved diagnostic accuracy, rigorous management of risk factors and unravelling of the genetic predisposition may represent strategies for improving prognosis.
Journal ArticleDOI
Race, APOL1 Risk, and eGFR Decline in the General Population
Morgan E. Grams,Casey M. Rebholz,Yuan Chen,Andreea M. Rawlings,Michelle M. Estrella,Elizabeth Selvin,Lawrence J. Appel,Adrienne Tin,Josef Coresh +8 more
TL;DR: The high variability in eGFR decline among blacks with and without the APOL1 high-risk genotype suggests that population-based screening is not yet justified, and the high risk for hypertension, diabetes, and ESRD in blacks only is suggested.
Journal ArticleDOI
Randomized controlled trial of strain-specific probiotic formulation (Renadyl) in dialysis patients.
Ranganathan Natarajan,Bohdan Pechenyak,Usha Vyas,Pari Ranganathan,Alan D. Weinberg,Peter Liang,Mary Mallappallil,Allen J. Norin,Eli A. Friedman,Subodh J. Saggi +9 more
TL;DR: Renadyl appeared to be safe to administer to ESRD patients on hemodialysis and stability in QOL assessment is an encouraging result for a patient cohort in such advanced stage of kidney disease.
References
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Scott M. Grundy,David W. Bilheimer,Alan Chait,Luther T. Clark,Margo A. Denke,Richard J. Havel,William R. Hazzard,Stephen B. Hulley,Donald B. Hunninghake,Robert A. Kreisberg,Penny M. Kris-Etherton,James M. McKenney,Michael A. Newman,Ernst J. Schaefer,Burton E. Sobel,Carolyn Somelofski,Milton C. Weinstein,H. Bryan Brewer,James I. Cleeman,Karen A. Donato,Nancy D. Ernst,Jeffrey M. Hoeg,Basil M. Rifkind,Jacques E. Rossouw,Christopher T. Sempos,Joanne M. Gallivan,Maureen N. Harris,Laurie Quint-Adler +27 more
TL;DR: Dairy therapy remains the first line of treatment of high blood cholesterol, and drug therapy is reserved for patients who are considered to be at high risk for CHD, and the fundamental approach to treatment is comparable.
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A New Equation to Estimate Glomerular Filtration Rate
Andrew S. Levey,Lesley A. Stevens,Christopher H. Schmid,Yaping (Lucy) Zhang,Alejandro F. Castro,Harold I. Feldman,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Tom Greene,Josef Coresh +10 more
TL;DR: The CKD-EPI creatinine equation is more accurate than the Modification of Diet in Renal Disease Study equation and could replace it for routine clinical use.
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Detection, Evaluation, and Treatment of High Blood Cholesterol Education Program (NCEP) Expert Panel on Executive Summary of the Third Report of the National
William C. Taylor,Nigel Unwin +1 more
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Prevalence of Chronic Kidney Disease in the United States
Josef Coresh,Elizabeth Selvin,Lesley A. Stevens,Jane Manzi,John W. Kusek,Paul W. Eggers,Frederick Van Lente,Andrew S. Levey +7 more
TL;DR: The prevalence of CKD in the United States in 1999-2004 is higher than it was in 1988-1994 and this increase is partly explained by the increasing prevalence of diabetes and hypertension and raises concerns about future increased incidence of kidney failure and other complications.
Journal ArticleDOI
Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: a collaborative meta-analysis.
Kunihiro Matsushita,Marije van der Velde,Brad C. Astor,Mark Woodward,Andrew S. Levey,Paul E. de Jong,Josef Coresh,Ron T. Gansevoort,Meguid El-Nahas,Kai-Uwe Eckardt,Bertram L. Kasiske,Marcello Tonelli,Brenda R. Hemmelgarn,Yaping Wang,Robert C. Atkins,Kevan R. Polkinghorne,Steven J. Chadban,Anoop Shankar,Ronald Klein,Barbara E.K. Klein,Haiyan Wang,Fang Wang,Luxia Zhang,Lisheng Liu,Michael G. Shlipak,Mark J. Sarnak,Ronit Katz,Linda Fried,Tazeen H. Jafar,M. Mazharul Islam,Juanita Hatcher,Neil R Poulter,Nish Chaturvedi,Dietrich Rothenbacher,Hermann Brenner,Elke Raum,Wolfgang Koenig,Caroline S. Fox,Shih-Jen Hwang,James B. Meigs,Massimo Cirillo,Stein Hallan,Stian Lydersen,Jostein Holmen,Paul Roderick,Dorothea Nitsch,Astrid E. Fletcher,Christopher J. Bulpitt,Takayoshi Ohkubo,Hirohito Metoki,Masaaki Nakayama,Masahiro Kikuya,Yutaka Imai,Simerjot K. Jassal,Elizabeth Barrett-Connor,Jaclyn Bergstrom,David G. Warnock,Paul Muntner,Suzanne E. Judd,William M. McClellan,Mary Cushman,George Howard,Leslie A. McClure,Sun Ha Jee,Heejin Kimm,Ji Eun Yun,Chi Pang Wen,Sung Feng Wen,Chwen Keng Tsao,Min Kuang Tsai,Johan Ärnlöv,Priscilla Auguste,Kasper Veldhuis,Laura Camarata,Beverly Thomas,Tom Manley +75 more
TL;DR: In this article, a meta-analysis of general population cohorts was conducted to assess the independent and combined associations of estimated glomerular filtration rate (eGFR) and albuminuria with mortality.
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