Journal ArticleDOI
Low molecular weight chitosans--preparation by depolymerization with Aspergillus niger pectinase, and characterization.
TLDR
CP-MAS 13C NMR showed marked changes in the chain conformations of LMWC, which are believed to be responsible for its loss of solubility and functionality.About:
This article is published in Carbohydrate Research.The article was published on 2003-06-16. It has received 153 citations till now. The article focuses on the topics: Aspergillus niger & Depolymerization.read more
Citations
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Journal ArticleDOI
Chitosan—A versatile semi-synthetic polymer in biomedical applications
TL;DR: The chemical structure and relevant biological properties of chitosan for regenerative medicine have been summarized as well as the methods for the preparation of controlled drug release devices and their applications.
Journal ArticleDOI
Biodegradation, biodistribution and toxicity of chitosan.
Thomas J. Kean,Maya Thanou +1 more
TL;DR: Research in this area is reviewed and chitosan's potential to be used as a generally regarded as safe (GRAS) material is critically discussed.
Journal ArticleDOI
Application of Spectroscopic Methods for Structural Analysis of Chitin and Chitosan
Jolanta Kumirska,Małgorzata Czerwicka,Zbigniew Kaczyński,Anna Bychowska,Krzysztof Brzozowski,Jorg Thöming,Piotr Stepnowski +6 more
TL;DR: A complete chemical and physicochemical characterization of chitin, chitosan and their derivatives is not possible without using spectroscopic techniques, so this review focuses on the application of Spectroscopic methods for the structural analysis of these compounds.
Journal ArticleDOI
Chitosan based hydrogels and their applications for drug delivery in wound dressings: A review
TL;DR: Applications and structural characteristics of different types of active ingredients, such as growth factors, nanoparticles, nanostructures, and drug loaded chitosan hydrogels are summarized.
Journal ArticleDOI
Chitosan Modification and Pharmaceutical/Biomedical Applications
TL;DR: This review summarizes chitosan modification and its pharmaceutical/biomedical applications based on achievements as well as the domestic and overseas developments.
References
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Journal ArticleDOI
Antimicrobial effect of chitooligosaccharides produced by bioreactor
TL;DR: In this paper, the antibacterial effect of three kinds of chitooligosaccharides with relatively higher molecular weights (HMWCOS), medium molecular weight (MMWCOS), and lower molecular weight, respectively, was evaluated against various microorganisms.
Journal ArticleDOI
Characterization of chitosan. Influence of ionic strength and degree of acetylation on chain expansion
TL;DR: This paper concerns a new method of characterizing chitosans with different degrees of acetylation using a multidetection instrument allowing determination of M, [eta] and RG for each point of the chromatograms, and Lp is found to be independent of DA in the range tested.
Journal ArticleDOI
The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrates for lysozyme.
TL;DR: Experiments studying the lysozyme-catalyzed hydrolysis of these oligosaccharides showed a large effect of chain length upon the rate of Hydrolysis, and no effect of ionic strength.
Journal ArticleDOI
Physical characterization of pharmaceutical solids.
Harry G. Brittain,Susan J. Bogdanowich,David E. Bugay,Joseph Devincentis,Geoffrey Lewen,Ann Newman +5 more
TL;DR: A general review of the methods available for the physical characterization of pharmaceutical solids is presented in this article, which is classified as being on the molecular level, the particulate level, and the bulk level.
Journal Article
On the physical characterization of pharmaceutical solids
TL;DR: Full physical characterization of three modifications of lactose is presented to illustrate the type of information which can be obtained using each of the techniques discussed.