Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Emily A. Holmes,Emily A. Holmes,Rory C. O'Connor,V. Hugh Perry,Irene Tracey,Simon Wessely,Louise Arseneault,Clive Ballard,Helen Christensen,Roxane Cohen Silver,Ian P. Everall,Tamsin Ford,Ann John,Thomas Kabir,Kate King,Ira Madan,Susan Michie,Andrew K. Przybylski,Roz Shafran,Angela Sweeney,Carol M. Worthman,Lucy Yardley,Katherine Cowan,Claire Cope,Matthew Hotopf,Edward T. Bullmore +25 more
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TLDR
There is an urgent need for research to address how mental health consequences for vulnerable groups can be mitigated under pandemic conditions, and on the impact of repeated media consumption and health messaging around COVID-19.About:
This article is published in The Lancet Psychiatry.The article was published on 2020-04-15 and is currently open access. It has received 3909 citations till now. The article focuses on the topics: Mental health & Psychological intervention.read more
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Examining the impacts of the COVID-19 pandemic on family mental health in Canada: findings from a national cross-sectional study.
Anne C Gadermann,Anne C Gadermann,Kimberly Thomson,Kimberly Thomson,Chris G. Richardson,Chris G. Richardson,Monique Gagné,Monique Gagné,Corey McAuliffe,Saima Hirani,Emily K. Jenkins +10 more
TL;DR: In this article, the authors describe the mental health impacts of the COVID-19 pandemic on families with children in Canada and identify changes in their interactions with their children, impacts on their children's mental health and sources of support accessed.
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Mental distress among U.S. adults during the COVID-19 pandemic
Jean M. Twenge,Thomas E. Joiner +1 more
TL;DR: Differences between the 2018 and 2020 samples appeared across all demographic groups, with larger differences among younger adults and those with children in the household.
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The Effect of COVID-19 on Mental Health and Wellbeing in a Representative Sample of Australian Adults
Amy Dawel,Yiyun Shou,Michael Smithson,Nicolas Cherbuin,Michelle Banfield,Alison L. Calear,Louise Farrer,Darren J. Gray,Amelia Gulliver,Tambri Housen,Sonia M. McCallum,Alyssa R. Morse,Kristen Murray,Eryn J. Newman,Rachael M. Rodney Harris,Philip J. Batterham +15 more
TL;DR: It is suggested that minimizing disruption to work and social functioning, and increasing access to mental health services in the community, are important policy goals to minimize pandemic-related impacts on mental health and wellbeing.
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Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A systematic review and meta-analysis.
TL;DR: In this article, the authors evaluated factors associated with psychological distress among the predominantly general population during the COVID-19 pandemic and found that higher infection risk, living in hard-hit areas, having pre-existing physical or mental conditions, and longer media exposure were associated with higher odds of anxiety and depression.
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Loneliness, Mental Health, and Substance Use among US Young Adults during COVID-19.
TL;DR: Estimates indicate elevated psychosocial symptomatology and suggest that symptoms could have worsened since the pandemic, underscore the importance of prevention and intervention to address these public health problems.
References
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Stress, appraisal, and coping
Richard S. Lazarus,Susan Folkman +1 more
TL;DR: In this paper, the authors present a detailed theory of psychological stress, building on the concepts of cognitive appraisal and coping, which have become major themes of theory and investigation in psychology.
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann,Hannah Kleine-Weber,Simon Schroeder,Nadine Krüger,Tanja Herrler,Sandra Erichsen,Tobias S. Schiergens,Georg Herrler,Nai Huei Wu,Andreas Nitsche,Marcel A. Müller,Christian Drosten,Christian Drosten,Stefan Pöhlmann +13 more
TL;DR: It is demonstrated that SARS-CoV-2 uses the SARS -CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming, and it is shown that the sera from convalescent SARS patients cross-neutralized Sars-2-S-driven entry.
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The psychological impact of quarantine and how to reduce it: rapid review of the evidence.
Samantha K Brooks,Rebecca K. Webster,Louise E. Smith,Lisa Woodland,Simon Wessely,Neil Greenberg,Gideon James Rubin +6 more
TL;DR: A review of the psychological impact of quarantine using three electronic databases is presented in this article, where the authors report negative psychological effects including post-traumatic stress symptoms, confusion, and anger.
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Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding.
Roujian Lu,Xiang Zhao,Juan Li,Peihua Niu,Bo Yang,Honglong Wu,Wenling Wang,Hao Song,Baoying Huang,Na Zhu,Yuhai Bi,Xuejun Ma,Faxian Zhan,Liang Wang,Tao Hu,Hong Zhou,Zhenhong Hu,Weimin Zhou,Li Zhao,Jing Chen,Yao Meng,Ji Wang,Yang Lin,Jianying Yuan,Zhihao Xie,Jinmin Ma,William J. Liu,Dayan Wang,Wenbo Xu,Edward C. Holmes,George F. Gao,George F. Gao,Guizhen Wu,Weijun Chen,Weifeng Shi,Wenjie Tan,Wenjie Tan +36 more
TL;DR: The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans.
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Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Daniel Wrapp,Nianshuang Wang,Kizzmekia S. Corbett,Jory A. Goldsmith,Ching-Lin Hsieh,Olubukola M. Abiona,Barney S. Graham,Jason S. McLellan +7 more
TL;DR: The authors show that this protein binds at least 10 times more tightly than the corresponding spike protein of severe acute respiratory syndrome (SARS)–CoV to their common host cell receptor, and test several published SARS-CoV RBD-specific monoclonal antibodies found that they do not have appreciable binding to 2019-nCoV S, suggesting that antibody cross-reactivity may be limited between the two RBDs.