Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range.
Thomas H. Marwick,Rodel Leano,Joseph Brown,Jing Ping Sun,Rainer Hoffmann,Peter Lysyansky,Michael Becker,James D. Thomas +7 more
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TLDR
This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1% and there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.Abstract:
The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of −18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.read more
Citations
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Journal ArticleDOI
Heart deformation analysis: measuring regional myocardial velocity with MR imaging.
TL;DR: By providing comparable velocity measures as TPM does, HDA may serve as an alternative for measuring regional myocardial velocity with a faster image processing procedure.
Journal ArticleDOI
A new integrated approach to cardiac mechanics: reference values for normal left ventricle
Giorgio Faganello,Dario Collia,Stefano Furlotti,Linda Pagura,Michele Zaccari,Gianni Pedrizzetti,Andrea Di Lenarda +6 more
TL;DR: A new integrated approach could differentiate normality from pathology by providing average deformation values and hemodynamic forces parameters, differentiated by age and gender, in a large cohort of healthy volunteers.
Journal ArticleDOI
Growth Hormone Deficiency in Adults Impacts Left Ventricular Mechanics: A Two-Dimensional Speckle-Tracking Study
Sorina Mihaila,Raluca I Mincu,Roxana Cristina Rimbas,Raluca Dulgheru,Ruxandra Dobrescu,Stefania L Magda,Corin Badiu,Dragos Vinereanu +7 more
TL;DR: In this paper, the authors assessed cardiac, arterial, and endothelial functions, using conventional and speckle-tracking echocardiography, in adults with growth hormone deficiency compared with controls with similar cardiovascular risk.
Journal ArticleDOI
Global longitudinal strain, ejection fraction, effort tolerance and normal echocardiography measurements in healthy Indians
TL;DR: The findings show healthy Indians, as compared to US and European population, to have higher relative wall thickness and normal reference values for echocardiographic measurements in healthy Indian population are presented.
Journal ArticleDOI
Evaluation of cardiac function by global longitudinal strain before and after treatment with sofosbuvir-based regimens in HCV infected patients
Maria Mazzitelli,Carlo Torti,Jolanda Sabatino,Greta Luana D’Ascoli,Chiara Costa,Vincenzo Pisani,Elena Raffetti,Salvatore De Rosa,Alessio Strazzulla,Alfredo Focà,Maria Carla Liberto,Ciro Indolfi +11 more
TL;DR: Results showed unexpected worsening of left ventricular function when measured through GLS after HCV treatment response induced by DAAs including sofosbuvir, although this result is not proven to be clinically significant.
References
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Journal ArticleDOI
Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function.
Marina Leitman,P. Lysyansky,Stanislav Sidenko,Vladimir Shir,Eli Peleg,Michal Binenbaum,Edo Kaluski,Ricardo Krakover,Zvi Vered +8 more
TL;DR: In this paper, the authors assess the feasibility of 2D strain, a software for real-time quantitative echocardiographic assessment of myocardial function, which is based on the estimation that a discrete set of tissue velocities are present per each of many small elements on the ultrasound image.
Journal ArticleDOI
Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans. Validation against three-dimensional tagged magnetic resonance imaging
TL;DR: The present study demonstrates the ability of Doppler echocardiography to measure myocardial strains in a clinical setting and may represent a new powerful method for quantifying left ventricular function noninvasively in humans.
Journal ArticleDOI
Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects
Mirosław Kowalski,Tomasz Kukulski,Fadi Jamal,Jan D'hooge,Frank Weidemann,Frank Rademakers,Bart Bijnens,Liv Hatle,George R. Sutherland +8 more
TL;DR: SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation, and values describing radial deformation were higher than the corresponding SR/ep silon values obtained for longitudinal deformation.
Journal ArticleDOI
Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
Jing Ping Sun,Zoran B. Popović,Neil L. Greenberg,Xiao Fang Xu,Craig R. Asher,William J. Stewart,James D. Thomas +6 more
TL;DR: Although myocardial velocities and strain rate showed significant dependence on age, displacement and peak systolic strain measures were less affected, and Doppler tissue echocardiography measurements showed a strong dependence on wall segment position.
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