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Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range.

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TLDR
This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1% and there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.
Abstract
The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of −18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.

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Citations
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[Degenerative aortic stenosis: prediction of poor prognosis by 2D left ventricular longitudinal strain in non-operated patients].

TL;DR: GLPS for the whole LV correlated with early ECG and ECHO parameters of LV hypertrophy and has prognostic value for one-year outcomes in patients with degenerative non-operated aortic stenosis.
Journal ArticleDOI

Myocardial Mass Corrected CMR Feature Tracking-Based Strain Ratios are Different in Pathologies With Increased Myocardial Mass

- 01 Apr 2022 - 
TL;DR: In this article , CMR left ventricular (LV) feature tracking (FT)-based strain parameters were indexed to myocardial mass index (LVMi) in order to evaluate potential additional value in the differentiation among acute myocarditis (AM), HHD, and healthy volunteers (HV) compared to non-indexed conventional strain.
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[Current recommendations for diagnostic echocardiography in cancer patients : Is echocardiography too late or too early?]

I Kruck
- 23 Feb 2017 - 
TL;DR: It has been found that additional analysis of the LV function using deformation imaging is a more accurate and sensitive tool for detecting subclinical systolic LV dysfunction.
References
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Journal ArticleDOI

Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function.

TL;DR: In this paper, the authors assess the feasibility of 2D strain, a software for real-time quantitative echocardiographic assessment of myocardial function, which is based on the estimation that a discrete set of tissue velocities are present per each of many small elements on the ultrasound image.
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Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans. Validation against three-dimensional tagged magnetic resonance imaging

TL;DR: The present study demonstrates the ability of Doppler echocardiography to measure myocardial strains in a clinical setting and may represent a new powerful method for quantifying left ventricular function noninvasively in humans.
Journal ArticleDOI

Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects

TL;DR: SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation, and values describing radial deformation were higher than the corresponding SR/ep silon values obtained for longitudinal deformation.
Journal ArticleDOI

Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging

TL;DR: Although myocardial velocities and strain rate showed significant dependence on age, displacement and peak systolic strain measures were less affected, and Doppler tissue echocardiography measurements showed a strong dependence on wall segment position.
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