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Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range.

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TLDR
This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1% and there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.
Abstract
The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of −18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.

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Journal ArticleDOI

Cardiac function in 10-year-old twins following different fetal therapies for twin-twin transfusion syndrome.

TL;DR: To compare cardiac function at 10 years of age in four groups of monochorionic diamniotic twin pairs, twins that had had twin–twin transfusion syndrome (TTTS) managed by amnioreduction or laser photocoagulation are compared.
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Evaluation of left ventricular global functions with speckle tracking echocardiography in patients recovered from COVID-19.

TL;DR: In this paper, the authors evaluated by global longitudinal strain whether there is subclinical myocardial deformation after COVID-19 infection and found that the deformation rate was higher in those who developed myocardious injury during hospitalization.
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Global longitudinal strain: a useful everyday measurement?

TL;DR: Analysis by direct comparison, intra-class correlation (ICC), coefficient of variation (CV) and Bland–Altman plots demonstrated that GLS is a more reproducible measurement than 2DEF, important to prevent clinical decisions being erroneously based on variation in operator measurement.
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Effects of Sedentary Aging and Lifelong Exercise on Left Ventricular Systolic Function.

TL;DR: Sedentary aging leads to a reduction in systolic LS, which is attenuated by committed lifelong exercise due to improved LV diastolic filling, which was independent of aging and lifelong exercise.
Journal ArticleDOI

Reversibility of left ventricular mechanical dysfunction in patients with hypertensive heart disease.

TL;DR: In patients with hypertensive heart disease and normal left ventricular ejection fraction, abnormalities inleft ventricular mechanical systolic function can be ameliorated in the setting of targeted antihypertensive treatment.
References
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Journal ArticleDOI

Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function.

TL;DR: In this paper, the authors assess the feasibility of 2D strain, a software for real-time quantitative echocardiographic assessment of myocardial function, which is based on the estimation that a discrete set of tissue velocities are present per each of many small elements on the ultrasound image.
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Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans. Validation against three-dimensional tagged magnetic resonance imaging

TL;DR: The present study demonstrates the ability of Doppler echocardiography to measure myocardial strains in a clinical setting and may represent a new powerful method for quantifying left ventricular function noninvasively in humans.
Journal ArticleDOI

Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects

TL;DR: SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation, and values describing radial deformation were higher than the corresponding SR/ep silon values obtained for longitudinal deformation.
Journal ArticleDOI

Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging

TL;DR: Although myocardial velocities and strain rate showed significant dependence on age, displacement and peak systolic strain measures were less affected, and Doppler tissue echocardiography measurements showed a strong dependence on wall segment position.
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