Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range.
Thomas H. Marwick,Rodel Leano,Joseph Brown,Jing Ping Sun,Rainer Hoffmann,Peter Lysyansky,Michael Becker,James D. Thomas +7 more
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TLDR
This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1% and there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.Abstract:
The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of −18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.read more
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Comparison of two different speckle tracking software systems: does the method matter?
Patric Biaggi,Shemy Carasso,Patrick Garceau,Matthias Greutmann,Christiane Gruner,Wendy Tsang,Harry Rakowski,Yoram Agmon,Anna Woo +8 more
TL;DR: TTP strain as well as strain gradients were comparable between VVI and 2DS, but most peak strain values were not, and the software‐dependency of peak strainvalues must be considered in clinical application.
Journal ArticleDOI
Unique Abnormalities in Right Ventricular Longitudinal Strain in Systemic Sclerosis Patients.
Monica Mukherjee,Shang En Chung,Von Khue Ton,Ryan J. Tedford,Laura K. Hummers,Fredrick M. Wigley,Theodore P. Abraham,Ami A. Shah +7 more
TL;DR: Speckle-derived strain reveals a heterogenous pattern of regional heart strain in SSc that is not detected by conventional measures of function, suggestive of occult RV myocardial disease.
Journal ArticleDOI
Echocardiographic parameters of left ventricular size and function as predictors of symptomatic heart failure in patients with a left ventricular ejection fraction of 50-59% treated with anthracyclines
Negareh Mousavi,Timothy C. Tan,Mohammed Ali,Elkan F. Halpern,Lin Wang,Marielle Scherrer-Crosbie +5 more
TL;DR: In patients treated with anthracyclines with an LVEF of 50-59%, both baseline EDV and GLS predict the occurrence of MACE, which may help target patients who could benefit from closer cardiac surveillance and earlier initiation of cardioprotective medical therapy.
Journal ArticleDOI
Murine Models of Diastolic Dysfunction and Heart Failure With Preserved Ejection Fraction
TL;DR: The fact that heart failure with preserved ejection fraction is difficult to diagnose in animal models and that, therefore, there is a paucity of well described animal models of this increasingly important condition is brought attention.
Journal ArticleDOI
Strain Echocardiography and Functional Capacity in Asymptomatic Primary Mitral Regurgitation With Preserved Ejection Fraction
Amgad Mentias,Peyman Naji,A. Marc Gillinov,L. Leonardo Rodriguez,Grant W. Reed,Tomislav Mihaljevic,Rakesh M. Suri,Joseph F. Sabik,Lars G. Svensson,Richard A. Grimm,Brian P. Griffin,Milind Y. Desai +11 more
TL;DR: Reduced exercise capacity and worsening resting LV-GLS were associated with mortality, providing additive prognostic utility in asymptomatic patients with ≥3+ primary MR and preserved left ventricular ejection fraction.
References
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Journal ArticleDOI
Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function.
Marina Leitman,P. Lysyansky,Stanislav Sidenko,Vladimir Shir,Eli Peleg,Michal Binenbaum,Edo Kaluski,Ricardo Krakover,Zvi Vered +8 more
TL;DR: In this paper, the authors assess the feasibility of 2D strain, a software for real-time quantitative echocardiographic assessment of myocardial function, which is based on the estimation that a discrete set of tissue velocities are present per each of many small elements on the ultrasound image.
Journal ArticleDOI
Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans. Validation against three-dimensional tagged magnetic resonance imaging
TL;DR: The present study demonstrates the ability of Doppler echocardiography to measure myocardial strains in a clinical setting and may represent a new powerful method for quantifying left ventricular function noninvasively in humans.
Journal ArticleDOI
Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects
Mirosław Kowalski,Tomasz Kukulski,Fadi Jamal,Jan D'hooge,Frank Weidemann,Frank Rademakers,Bart Bijnens,Liv Hatle,George R. Sutherland +8 more
TL;DR: SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation, and values describing radial deformation were higher than the corresponding SR/ep silon values obtained for longitudinal deformation.
Journal ArticleDOI
Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
Jing Ping Sun,Zoran B. Popović,Neil L. Greenberg,Xiao Fang Xu,Craig R. Asher,William J. Stewart,James D. Thomas +6 more
TL;DR: Although myocardial velocities and strain rate showed significant dependence on age, displacement and peak systolic strain measures were less affected, and Doppler tissue echocardiography measurements showed a strong dependence on wall segment position.
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