Myocardial strain measurement with 2-dimensional speckle-tracking echocardiography: definition of normal range.
Thomas H. Marwick,Rodel Leano,Joseph Brown,Jing Ping Sun,Rainer Hoffmann,Peter Lysyansky,Michael Becker,James D. Thomas +7 more
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TLDR
This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 +/- 0.1% and there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.Abstract:
The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of −18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.read more
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Left ventricular strain and strain rate by 2D speckle tracking in chronic thromboembolic pulmonary hypertension before and after pulmonary thromboendarterectomy
Nicholas Olson,Jason P. Brown,Andrew M. Kahn,William R. Auger,Michael M. Madani,Thomas J. Waltman,Daniel G. Blanchard +6 more
TL;DR: LV circumferential and posterior wall radial strain change after relief of pulmonary arterial obstruction in patients with CTEPH, and these improvements occur rapidly, which may reflect effects from improved LV diastolic filling, and may be useful non-invasive markers of successful PTE.
Journal ArticleDOI
The potential role of echocardiographic strain imaging for evaluating cardiotoxicity due to cancer therapy
TL;DR: In this article, the authors reviewed the recent literature and explored the potential role of myocardial strain imaging in cancer management and avenues for future research, and found that strain analysis has the potential to detect early sub-clinical changes in cardiac function due to cardiotoxicity.
Journal ArticleDOI
Speckle tracking echocardiography-determined measures of global and regional left ventricular function correlate with functional capacity in patients with and without preserved ejection fraction
TL;DR: STE–determined measures of strain, especially longitudinal strain, are likely to be important targets for therapy and should be considered in future studies aimed at improving the diagnosis of left ventricular inadequacy in patients with heart failure, especially those with preserved ejection fraction.
Journal ArticleDOI
The relationship between left ventricular structure and function in the elite rugby football league athlete as determined by conventional echocardiography and myocardial strain imaging.
Lynsey Forsythe,David H. MacIver,Christopher Johnson,Keith George,John Somauroo,Michael Papadakis,Benjamin Brown,Mohammad Qasem,David Oxborough +8 more
TL;DR: Normal EF is explained by divergent effects of LV internal diastolic dimension (LVIDd) and mean wall thickness (MWT) on LV function, and reductions in SR and twist may be part of normal physiological LV adaptation in RFL athletes.
Journal ArticleDOI
Association of Noninvasively Measured Left Ventricular Mechanics With In Vitro Muscle Contractile Performance: A Prospective Study in Hypertrophic Cardiomyopathy Patients
Ashwat Dhillon,Wendy E. Sweet,Zoran B. Popović,Nicholas G. Smedira,Maran Thamilarasan,Bruce W. Lytle,Carmela D. Tan,Randall C. Starling,Harry M. Lever,Christine S. Moravec,Milind Y. Desai +10 more
TL;DR: Left ventricular mechanics (echocardiographic longitudinal systolic strain and diastolic strain rates), assessed at the basal septum and histopathologic findings characteristic for HCM were significantly associated with in vitro myocardial resting and developed contractile performance.
References
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Journal ArticleDOI
Two-dimensional strain-a novel software for real-time quantitative echocardiographic assessment of myocardial function.
Marina Leitman,P. Lysyansky,Stanislav Sidenko,Vladimir Shir,Eli Peleg,Michal Binenbaum,Edo Kaluski,Ricardo Krakover,Zvi Vered +8 more
TL;DR: In this paper, the authors assess the feasibility of 2D strain, a software for real-time quantitative echocardiographic assessment of myocardial function, which is based on the estimation that a discrete set of tissue velocities are present per each of many small elements on the ultrasound image.
Journal ArticleDOI
Quantitative assessment of intrinsic regional myocardial deformation by Doppler strain rate echocardiography in humans. Validation against three-dimensional tagged magnetic resonance imaging
TL;DR: The present study demonstrates the ability of Doppler echocardiography to measure myocardial strains in a clinical setting and may represent a new powerful method for quantifying left ventricular function noninvasively in humans.
Journal ArticleDOI
Can natural strain and strain rate quantify regional myocardial deformation? A study in healthy subjects
Mirosław Kowalski,Tomasz Kukulski,Fadi Jamal,Jan D'hooge,Frank Weidemann,Frank Rademakers,Bart Bijnens,Liv Hatle,George R. Sutherland +8 more
TL;DR: SR/epsilon imaging appears to be a robust technique for quantifying regional myocardial deformation, and values describing radial deformation were higher than the corresponding SR/ep silon values obtained for longitudinal deformation.
Journal ArticleDOI
Noninvasive quantification of regional myocardial function using Doppler-derived velocity, displacement, strain rate, and strain in healthy volunteers: effects of aging
Jing Ping Sun,Zoran B. Popović,Neil L. Greenberg,Xiao Fang Xu,Craig R. Asher,William J. Stewart,James D. Thomas +6 more
TL;DR: Although myocardial velocities and strain rate showed significant dependence on age, displacement and peak systolic strain measures were less affected, and Doppler tissue echocardiography measurements showed a strong dependence on wall segment position.
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