Journal ArticleDOI
Nanoparticles and its biomedical applications in health and diseases: special focus on drug delivery.
Nuzhat Zahin,Raihanatul Anwar,Devesh Tewari,Md. Tanvir Kabir,Amin Sajid,Bijo Mathew,Md. Sahab Uddin,Lotfi Aleya,Mohamed M. Abdel-Daim +8 more
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TLDR
This review focuses on the detailed profile of NPs, its impact on biology and medicine, and their commercialization prospects.Abstract:
Nanotechnology is an emerging technology that deals with nanosized particles possessing crucial research roles and application. Disciplines like chemistry, biology, physics, engineering, materials science, and health sciences provide an accumulated knowledge of nanotechnology. Nonetheless, it has vast submissions precisely in biology, electronics, and medicine. Aimed at drug delivery system, nanoparticles are based on the mechanism of entrapment of the drugs or biomolecules into the interior structure of the particles; another mechanism could be that the drugs or the biomolecules can be absorbed onto the exterior surfaces of the particles. Currently, nanoparticles (NPs) are used in the delivery of drugs, proteins, genes, vaccines, polypeptides, nucleic acids, etc. In recent years, various applications of the drug delivery system via NPs have encountered an enormous position sector like pharmaceutical, medical, biological, and others. Considering the impact of NPs in drug delivery systems, this review focuses on the detailed profile of NPs, its impact on biology and medicine, and their commercialization prospects.read more
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Magnetic nanoparticles for hyperthermia in cancer treatment: an emerging tool
Jobin Jose,Rajesh Kumar,Seetha Harilal,Githa Elizabeth Mathew,Della Grace Thomas Parambi,Ankitha Prabhu,Sahab Uddin,Lotfi Aleya,Hoon Kim,Bijo Mathew +9 more
TL;DR: The utilization of magnetic nanoparticles (MNPs) offers functionalities not possible using conventional magnetic materials, and recent developments and applications of MNPs for hyperthermic treatment are detailed and discussed.
Journal Article
In vivo imaging with quantum dots encapsulated in phospholipid micelles
TL;DR: In this paper, the authors encapsulated individual nanocrystals in phospholipid block-copolymer micelles and demonstrated both in vitro and in vivo imaging, and the nanocrystal-micelles acted as in vitro fluorescent probes to hybridize to specific complementary sequences.
Journal ArticleDOI
Advancements in nanotherapeutics for Alzheimer's disease: current perspectives.
Seetha Harilal,Jobin Jose,Della Grace Thomas Parambi,Rajesh Kumar,Githa Elizabeth Mathew,Sahab Uddin,Hoon Kim,Bijo Mathew +7 more
TL;DR: Significant progress has been made in the treatment of Alzheimer’s disease, but all available strategies focus on alleviating symptoms rather than curing, which means that AD is viewed as an unresolvable neurodegenerative disease.
Journal ArticleDOI
Recent Advances in Zinc Oxide Nanoparticles (ZnO NPs) for Cancer Diagnosis, Target Drug Delivery, and Treatment.
Sumaira Anjum,Mariam Hashim,Sara Asad Malik,Maha Khan,José M. Lorenzo,Bilal Haider Abbasi,Christophe Hano +6 more
TL;DR: In this article, the role of zinc oxide nanoparticles (ZnO NPs) in diagnosis and bio-imaging of cancer cells is discussed, with a special focus on surface functionalization, drugloading mechanism, and stimuli-responsive controlled release of drugs.
Journal ArticleDOI
Metal-based nanoparticles, sensors, and their multifaceted application in food packaging.
TL;DR: In this article, the authors highlight the use of green mode-based synthesized nanoparticles (NPs) for prominent applications of antimicrobial properties, nanosensors, and food packaging of food items.
References
More filters
Journal ArticleDOI
Hallmarks of cancer: the next generation.
TL;DR: Recognition of the widespread applicability of these concepts will increasingly affect the development of new means to treat human cancer.
Journal ArticleDOI
C 60 : Buckminsterfullerene
Harold W. Kroto,Harold W. Kroto,James R. Heath,Sean C. O'Brien,Robert F. Curl,Richard E. Smalley +5 more
TL;DR: In this article, the authors proposed a truncated icosahedron, a polygon with 60 vertices and 32 faces, 12 of which are pentagonal and 20 hexagonal.
Journal ArticleDOI
Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications
Ajay Kumar Gupta,Mona Gupta +1 more
TL;DR: This review discusses the synthetic chemistry, fluid stabilization and surface modification of superparamagnetic iron oxide nanoparticles, as well as their use for above biomedical applications.
Journal ArticleDOI
Understanding biophysicochemical interactions at the nano–bio interface
Andre E. Nel,Lutz Mädler,Darrell Velegol,Tian Xia,Eric M.V. Hoek,Ponisseril Somasundaran,Fred Klaessig,Vince Castranova,Mike Thompson +8 more
TL;DR: Probing the various interfaces of nanoparticle/biological interfaces allows the development of predictive relationships between structure and activity that are determined by nanomaterial properties such as size, shape, surface chemistry, roughness and surface coatings.
Journal ArticleDOI
Renal clearance of quantum dots.
Hak Soo Choi,Wenhao Liu,Preeti Misra,Eiichi Tanaka,John P. Zimmer,Binil Itty Ipe,Moungi G. Bawendi,John V. Frangioni,John V. Frangioni +8 more
TL;DR: This study has precisely defined the requirements for renal filtration and urinary excretion of inorganic, metal-containing nanoparticles and provides a foundation for the design and development of biologically targeted nanoparticles for biomedical applications.
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