Journal ArticleDOI
Parasite-derived microRNAs in plasma as novel promising biomarkers for the early detection of hydatid cyst infection and post-surgery follow-up.
Zahra Alizadeh,Mahmoud Mahami-Oskouei,Adel Spotin,Tohid Kazemi,Ehsan Ahmadpour,Pengfei Cai,Dariush Shanehbandi,Najibeh Shekari +7 more
TLDR
It seems that these parasite-derived miRNAs, especially egr-miR-71, could serve as novel promising biomarkers for the early diagnosis and monitoring of hydatidosis.About:
This article is published in Acta Tropica.The article was published on 2020-02-01. It has received 29 citations till now. The article focuses on the topics: Echinococcus granulosus.read more
Citations
More filters
Journal ArticleDOI
Human microRNAs in host-parasite interaction: a review.
Sujay Paul,Luis M. Ruiz-Manriquez,Francisco I Serrano-Cano,Carolina Estrada-Meza,Karla A Solorio-Diaz,Aashish Srivastava,Aashish Srivastava +6 more
TL;DR: The impact of human microRNAs during host−parasite interaction as well as their potential to be used for diagnosis and prognosis purposes are demonstrated.
Journal ArticleDOI
Parasitic Helminth-Derived microRNAs and Extracellular Vesicle Cargos as Biomarkers for Helminthic Infections.
TL;DR: In this article, the authors discuss the status and potential of helminth-derived circulating miRNAs and extracellular vesicles (EVs) as novel diagnostic tools.
Journal ArticleDOI
The characterization of extracellular vesicles-derived microRNAs in Thai malaria patients
Nutpakal Ketprasit,Iris Simone Cheng,Fiona Deutsch,Nham Tran,Mallika Imwong,Valery Combes,Duangdao Palasuwan +6 more
TL;DR: Bioinformatic analysis revealed that EV specific miRNAs might regulate genes involved in the malaria pathway including the adherens junction and the transforming growth factor-β pathways and could potentially be used as disease biomarkers as determined by AUC.
Journal ArticleDOI
MicroRNA Interference in Hepatic Host-Pathogen Interactions.
TL;DR: In this article, the authors summarize the relationship between the immunological interactions of various pathogens and hepatic resident immune cells, as well as the role of miRNAs in the maintenance of liver immunity against pathogens.
Journal ArticleDOI
Highlighting the interplay of microRNAs from Leishmania parasites and infected-host cells.
Sajad Rashidi,Reza Mansouri,Mohammad Ali-Hassanzadeh,Esmaeel Ghani,Afshin Barazesh,Mohammadreza Karimazar,Paul Nguewa,Eugenio Antonio Carrera Silva +7 more
TL;DR: In this article, a review aims to address the differentially expressed miRNAs in both, the parasite and infected host cells and how these biomolecules change cell signalling and host immune responses during infection.
References
More filters
Journal ArticleDOI
Analysis of relative gene expression data using real-time quantitative pcr and the 2(-delta delta c(t)) method
TL;DR: The 2-Delta Delta C(T) method as mentioned in this paper was proposed to analyze the relative changes in gene expression from real-time quantitative PCR experiments, and it has been shown to be useful in the analysis of realtime, quantitative PCR data.
Journal ArticleDOI
Circulating microRNAs as stable blood-based markers for cancer detection
Patrick S. Mitchell,Rachael K. Parkin,Evan M. Kroh,Brian R. Fritz,Brian R. Fritz,Stacia K. Wyman,Era L. Pogosova-Agadjanyan,Amelia Peterson,Jennifer Noteboom,Kathy O'Briant,April Allen,Daniel W. Lin,Daniel W. Lin,Daniel W. Lin,Nicole Urban,Charles W. Drescher,Beatrice S. Knudsen,Derek L. Stirewalt,Robert Gentleman,Robert L. Vessella,Robert L. Vessella,Peter S. Nelson,Daniel Martin,Daniel Martin,Muneesh Tewari +24 more
TL;DR: It is shown here that miRNAs are present in human plasma in a remarkably stable form that is protected from endogenous RNase activity and established the measurement of tumor-derived mi RNAs in serum or plasma as an important approach for the blood-based detection of human cancer.
Journal ArticleDOI
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
Xi Chen,Yi Ba,Lijia Ma,Lijia Ma,Xing Cai,Yuan Yin,Kehui Wang,Jigang Guo,Yujing Zhang,Jiangning Chen,Xing Guo,Qibin Li,Qibin Li,Xiaoying Li,Wenjing Wang,Yan Zhang,Jin Wang,Xueyuan Jiang,Yang Xiang,Chen Xu,Pingping Zheng,Juanbin Zhang,Ruiqiang Li,Hongjie Zhang,Xiaobin Shang,Ting Gong,Guang Ning,Jun Wang,Jun Wang,Ke Zen,Junfeng Zhang,Chen-Yu Zhang +31 more
TL;DR: It is demonstrated that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves, and horses, and can serve as potential biomarkers for the detection of various cancers and other diseases.
Journal ArticleDOI
miRBase: integrating microRNA annotation and deep-sequencing data
Ana Kozomara,Sam Griffiths-Jones +1 more
TL;DR: This work has mapped reads from short RNA deep-sequencing experiments to microRNAs in miRBase and developed web interfaces to view these mappings, which can be used as a proxy for relative expression levels of microRNA sequences, provide detailed evidence for microRNA annotations and alternative isoforms of mature micro RNAs, and allow us to revisit previous annotations.
Journal ArticleDOI
The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes
TL;DR: Exosomal miRNA should be the starting point for early biomarker studies to reduce the probability of false negative results involving low abundance miRNAs that may be missed by using unfractionated serum or saliva.