Pediatric delirium and associated risk factors: a single-center prospective observational study.
Gabrielle Silver,Chani Traube,Linda M. Gerber,Xuming Sun,Julia Kearney,Anita Patel,Bruce M. Greenwald +6 more
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TLDR
In this institution, pediatric delirium is a prevalent problem, with identifiable risk factors, and further large-scale prospective studies are required to explore multi-institutional prevalence, modifiablerisk factors, therapeutic interventions, and effect on long-term outcomes.Abstract:
Objective:To describe a single-institution pilot study regarding prevalence and risk factors for delirium in critically ill children.Design:A prospective observational study, with secondary analysis of data collected during the validation of a pediatric delirium screening tool, the Cornell Assessmenread more
Citations
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Journal ArticleDOI
Clinical recommendations for pain, sedation, withdrawal and delirium assessment in critically ill infants and children: an ESPNIC position statement for healthcare professionals
Julia Harris,Anne-Sylvie Ramelet,Monique van Dijk,Pavla Pokorná,Pavla Pokorná,Pavla Pokorná,Joke M. Wielenga,Lyvonne N Tume,Dick Tibboel,Erwin Ista +9 more
TL;DR: This multidisciplinary ESPNIC position statement guides professionals in the assessment and reassessment of the effectiveness of treatment interventions for pain, distress, inadequate sedation, withdrawal syndrome and delirium.
Journal ArticleDOI
Delirium and Mortality in Critically Ill Children: Epidemiology and Outcomes of Pediatric Delirium.
Chani Traube,Gabrielle Silver,Linda M. Gerber,Savneet Kaur,Elizabeth Mauer,Abigail Kerson,Christine Joyce,Bruce M. Greenwald +7 more
TL;DR: The frequency of delirium in critically ill children, its duration, associated risk factors, and effect on in-hospital outcomes, including mortality are described, with a strong and independent predictor of mortality.
Journal ArticleDOI
Delirium in Critically Ill Children: An International Point Prevalence Study∗
Chani Traube,Gabrielle Silver,Ron W Reeder,Hannah Doyle,Emily Hegel,Heather Wolfe,Christopher Schneller,Melissa Chung,Leslie A. Dervan,Jane L. Digennaro,Sandra Buttram,Sapna R. Kudchadkar,Kate Madden,Mary E. Hartman,Mary DeAlmeida,Karen Walson,Erwin Ista,Manuel A. Baarslag,Rosanne Salonia,John Beca,Debbie Long,Yu Kawai,Ira M. Cheifetz,Javier Gelvez,Edward J. Truemper,Rebecca Smith,Megan E. Peters,Am Iqbal O’Meara,Sarah Murphy,Abdulmohsen Bokhary,Bruce M. Greenwald,Michael J. Bell +31 more
TL;DR: In this article, a multi-institutional point prevalence study was conducted to determine prevalence of delirium in critically ill children and explore associated risk factors, including age less than 2 years, mechanical ventilation, benzodiazepines, narcotics, use of physical restraints, and exposure to vasopressors and antiepileptics.
Journal ArticleDOI
Paediatric emergence delirium: a comprehensive review and interpretation of the literature
TL;DR: Emergence delirium should be considered as a ‘vital sign’, which should be followed and documented in every child in the postanaesthesia recovery period, and standardized screening tools should be adopted.
Journal ArticleDOI
Cost Associated with Pediatric Delirium in the ICU
Chani Traube,Elizabeth Mauer,Linda M. Gerber,Savneet Kaur,Christine Joyce,Abigail Kerson,Charlene Carlo,Daniel A. Notterman,Stefan Worgall,Gabrielle Silver,Bruce M. Greenwald +10 more
TL;DR: Pediatric delirium is associated with a major increase in PICU costs and further research directed at prevention and treatment of Pediatrics is essential to improve outcomes in this population and could lead to substantial healthcare savings.
References
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Journal ArticleDOI
Clinical Practice Guidelines for the Management of Pain, Agitation, and Delirium in Adult Patients in the Intensive Care Unit
Juliana Barr,Gilles L. Fraser,Kathleen Puntillo,E. Wesley Ely,Céline Gélinas,Joseph F. Dasta,Judy E. Davidson,John W. Devlin,John P. Kress,Aaron M. Joffe,Douglas B. Coursin,Daniel Herr,Avery Tung,Bryce R.H. Robinson,Dorrie K. Fontaine,Michael A. E. Ramsay,Richard R. Riker,Curtis N. Sessler,Brenda T. Pun,Yoanna Skrobik,Roman Jaeschke +20 more
TL;DR: These guidelines provide a roadmap for developing integrated, evidence-based, and patient-centered protocols for preventing and treating pain, agitation, and delirium in critically ill patients.
Journal ArticleDOI
The Richmond Agitation-Sedation Scale Validity and Reliability in Adult Intensive Care Unit Patients
Curtis N. Sessler,Mark S. Gosnell,Mary Jo Grap,Gretchen M. Brophy,Pam V. O'Neal,Kimberly A. Keane,Eljim P. Tesoro,Ronald K. Elswick +7 more
TL;DR: RASS has high reliability and validity in medical and surgical, ventilated and nonventilated, and sedated and nonsedated adult ICU patients and is described as logical, easy to administer, and readily recalled.
Journal ArticleDOI
The role and interpretation of pilot studies in clinical research
TL;DR: The roles and limitations of pilot studies are described here using a clinical trial as an example to evaluate the feasibility of recruitment, randomization, retention, assessment procedures, new methods, and implementation of the novel intervention.
Journal ArticleDOI
Sleep duration from infancy to adolescence: reference values and generational trends.
TL;DR: In this article, the authors calculate percentile curves for total sleep duration per 24 hours, for nighttime and for daytime sleep duration from early infancy to late adolescence to illustrate the developmental course and age-specific variability of these variables among subjects.
Journal ArticleDOI
Delirium as a predictor of long-term cognitive impairment in survivors of critical illness
Timothy D. Girard,James C. Jackson,Pratik P. Pandharipande,Brenda T. Pun,Jennifer L. Thompson,Ayunni K. Shintani,Sharon M. Gordon,Angelo E. Canonico,Robert S. Dittus,Gordon R. Bernard,E. Wesley Ely +10 more
TL;DR: In this study of mechanically ventilated medical intensive care unit patients, duration of delirium was independently associated with long-term cognitive impairment, a common public health problem amongintensive care unit survivors.
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