Journal ArticleDOI
Physiology of Vasopressin Relevant to Management of Septic Shock
TLDR
Clinical use of vasopressin should await a randomized controlled trial of its effects on clinical outcomes such as organ failure and mortality, because clinical studies have been relatively small, focused on physiologic end points, and because of potential adverse effects of vasipressin.About:
This article is published in Chest.The article was published on 2001-09-01. It has received 544 citations till now. The article focuses on the topics: Vasopressin & Vasopressin receptor.read more
Citations
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Journal ArticleDOI
Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012.
R. P. Dellinger,Mitchell M. Levy,Andrew Rhodes,Djillali Annane,Herwig Gerlach,Steven M. Opal,Jonathan E. Sevransky,Charles L. Sprung,Ivor S. Douglas,Roman Jaeschke,Tiffany M. Osborn,Mark E. Nunnally,Konrad Reinhart,Ruth M. Kleinpell,Derek C. Angus,Clifford S. Deutschman,Flávia Ribeiro Machado,Gordon D. Rubenfeld,Steven A R Webb,Richard Beale,Jean Louis Vincent,Rui Moreno +21 more
TL;DR: An update to the “Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock,” last published in 2008 is provided.
Journal ArticleDOI
Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012
R. Phillip Dellinger,Mitchell M. Levy,Andrew Rhodes,Djillali Annane,Herwig Gerlach,Steven M. Opal,Jonathan E. Sevransky,Charles L. Sprung,Ivor S. Douglas,Roman Jaeschke,Tiffany M. Osborn,Mark E. Nunnally,Sean R. Townsend,Konrad Reinhart,Ruth M. Kleinpell,Derek C. Angus,Clifford S. Deutschman,Flávia Ribeiro Machado,Gordon D. Rubenfeld,Steven A R Webb,Richard Beale,Jean Louis Vincent,Rui Moreno +22 more
TL;DR: A consensus committee of 68 international experts representing 30 international organizations was convened in 2008 to provide an update to the "Surviving Sepsis Campaign Guidelines for Management of Severe Sepsis and Septic Shock".
Journal ArticleDOI
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.
R. Phillip Dellinger,Mitchell M. Levy,J. Carlet,Julian Bion,Margaret M. Parker,Roman Jaeschke,Konrad Reinhart,Derek C. Angus,Christian Brun-Buisson,Richard Beale,Thierry Calandra,JF Dhainaut,Herwig Gerlach,Maurene A. Harvey,John J. Marini,John C. Marshall,Marco Ranieri,Graham Ramsay,Jonathan E. Sevransky,B. Taylor Thompson,Sean R. Townsend,Jeffrey S. Vender,Janice L. Zimmerman,Jean Louis Vincent +23 more
TL;DR: In this paper, the authors provide an update to the original Surviving Sepsis Campaign clinical management guidelines for management of severe sepsis and septic shock, published in 2004.
Surviving sepsis campaign: international guidelines for the management of severe sepsis and septic shock: 2008
TL;DR: To provide an update to the original Surviving Sepsis Campaign clinical management guidelines, the GRADE system was used to guide assessment of quality of evidence from high (A) to very low (D) and to determine the strength of recommendations.
Journal ArticleDOI
Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock
R. Phillip Dellinger,Jean Carlet,Henry Masur,Herwig Gerlach,Thierry Calandra,Jonathan Cohen,Juan Gea-Banacloche,Didier Keh,John C. Marshall,Margaret M. Parker,Graham Ramsay,Janice L. Zimmerman,Jean Louis Vincent,Mitchell M. Levy +13 more
TL;DR: Evidence-based recommendations can be made regarding many aspects of the acute management of sepsis and septic shock that will hopefully translate into improved outcomes for the critically ill patient.
References
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Journal ArticleDOI
Physiological roles and properties of potassium channels in arterial smooth muscle
Mark T. Nelson,J. M. Quayle +1 more
TL;DR: The main conclusions of this review are: 1) regulation of arterial smooth muscle membrane potential through activation or inhibition of K+ channel activity provides an important mechanism to dilate or constrict arteries; 2) KV, KCa, KIR, and KATP channels serve unique functions in the regulation of artery membrane potential
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A 3-level prognostic classification in septic shock based on cortisol levels and cortisol response to corticotropin.
Djillali Annane,Véronique Sébille,Gilles Troché,Jean Claude Raphael,Philippe Gajdos,Eric Bellissant +5 more
TL;DR: The data suggest that a short corticotropin test has a good prognostic value and could be helpful in identifying patients with septic shock at high risk for death.
Journal ArticleDOI
Vasopressin Deficiency Contributes to the Vasodilation of Septic Shock
Donald W. Landry,Howard R. Levin,Ellen M. Gallant,Robert C. Ashton,Susan K. Seo,David A. D'Alessandro,Mehmet C. Oz,Juan A. Oliver +7 more
TL;DR: Vasopressin plasma levels are inappropriately low in vasodilatory shock, most likely because of impaired baroreflex-mediated secretion.
Journal ArticleDOI
Vasopressinergic Control of Pituitary Adrenocorticotropin Secretion Comes of Age
TL;DR: By citing examples from physiological studies on the regulation of ACTH secretion, it is shown how the multicomponent hypothalamic regulatory system operates, emphasizing the considerable signal integrating role of the adenohypophysial corticotrope cell.
Journal ArticleDOI
The osmoregulation of vasopressin.
TL;DR: New assay methods now have made it possible to begin to characterize osmoregulatory function in a more concrete and comprehensive way and also to use such information to analyze systematically certain clinical disorders of salt and water balance.