Journal ArticleDOI
Polymer microfluidic devices
Holger Becker,Laurie E. Locascio +1 more
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TLDR
This article presents a review of polymer-based microfluidic systems including their material properties, fabrication methods, device applications, and finally an analysis of the market that drives their development.About:
This article is published in Talanta.The article was published on 2002-02-11. It has received 1150 citations till now.read more
Citations
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Journal ArticleDOI
The autofluorescence of plastic materials and chips measured under laser irradiation
Aigars Piruska,Irena Nikcevic,Se Hwan Lee,Chong H. Ahn,William R. Heineman,Patrick A. Limbach,Carl J. Seliskar +6 more
TL;DR: Intrinsic optical constants of plastic materials-refractive index for bulk materials-determined by spectroscopic ellipsometry and transmission spectroscopy in the visible range are presented and overall, the longer wavelength laser excitation sources yielded less autofluorescence.
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Micromilling: a method for ultra-rapid prototyping of plastic microfluidic devices
David J. Guckenberger,Theodorus E. de Groot,Alwin M. D. Wan,David J. Beebe,Edmond W. K. Young +4 more
TL;DR: This tutorial review offers protocols, tips, insight, and considerations for practitioners interested in using micromilling to create microfluidic devices to provide a potential user with information to guide them on whethermicromilling would fill a specific need within their overall fabrication strategy.
Journal ArticleDOI
Microfluidic cell culture systems for drug research.
TL;DR: This review starts with a comprehensive discussion on the general process for drug discovery and development, the role of cell culture in drug research, and the characteristics of the cell culture formats commonly used in current microfluidic-based, cell-culture practices.
Journal ArticleDOI
Paper-Based Microfluidic Devices: Emerging Themes and Applications
TL;DR: This work focuses on three-Dimensional Electrochemical Detection, which automates the very labor-intensive and therefore time-heavy and expensive process of characterize and characterize the electrochemical activity of the response of the immune system.
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Functional Nanomaterials and Nanostructures Enhancing Electrochemical Biosensors and Lab-on-a-Chip Performances: Recent Progress, Applications, and Future Perspective.
TL;DR: This review answers many questions around the nanomaterials used, their inherent properties and the chemistries they offer that are of interest to the analytical systems, and their roles in analytical applications in the past 5 years (2013-2018), and it gives a quantitative assessment of their positive effects on the analyses.
References
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Book
CRC Handbook of Chemistry and Physics
TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Journal ArticleDOI
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
Journal ArticleDOI
Fabrication of microfluidic systems in poly(dimethylsiloxane)
J.C. McDonald,David C. Duffy,Janelle R. Anderson,Daniel T. Chiu,Hongkai Wu,Olivier Schueller,George M. Whitesides +6 more
TL;DR: Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
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A Sequencing Method Based on Real-Time Pyrophosphate
Journal ArticleDOI
Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip
TL;DR: In this article, the authors demonstrated a miniaturized system for sample handling and separation using electrophoresis-based separations of amino acids with up to 75,000 theoretical plates in about 15 seconds.