Journal ArticleDOI
Polymer microfluidic devices
Holger Becker,Laurie E. Locascio +1 more
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TLDR
This article presents a review of polymer-based microfluidic systems including their material properties, fabrication methods, device applications, and finally an analysis of the market that drives their development.About:
This article is published in Talanta.The article was published on 2002-02-11. It has received 1150 citations till now.read more
Citations
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Journal ArticleDOI
Chitosan-mediated in situ biomolecule assembly in completely packaged microfluidic devices.
Jung Jin Park,Xiaolong Luo,Hyunmin Yi,Theresa Michelle Valentine,Gregory F. Payne,Gregory F. Payne,William E. Bentley,William E. Bentley,Reza Ghodssi,Gary W. Rubloff +9 more
TL;DR: Both in situ fluorescence and ex situ profilometer results confirm chitosan-mediated in situ biomolecule assembly, demonstrating a simple approach to direct the assembly of biological components into a completely fabricated device.
Patent
Apparatus for manipulating droplets
TL;DR: In this article, an apparatus for manipulating droplets on a substrate is described. But it is not shown how to manipulate a droplet on a surface of the substrate, nor how to control the droplet's motion.
Journal ArticleDOI
Adsorption of Proteins to Thin-Films of PDMS and Its Effect on the Adhesion of Human Endothelial Cells.
Karin Y. Chumbimuni-Torres,Ramon Coronado,Adelphe M. Mfuh,Carlos Fernando Castro-Guerrero,María Fernanda Silva,George R. Negrete,Rena Bizios,Carlos D. Garcia +7 more
TL;DR: Th thin-films of poly(dimethylsiloxane) can be used to model the surface properties of microdevices fabricated with commercial PDMS and guidelines to efficiently attach cells in BioMEMS devices are provided.
Journal ArticleDOI
Micro/nanotribological characterization of PDMS and PMMA used for BioMEMS/NEMS applications
TL;DR: In this paper, the adhesion and friction of single crystal silicon with native oxide layer and two polymers (poly(dimethylsiloxane) (PDMS) and poly(methylmethacrylate) (PMMA) are studied and their dependence on rest time, relative humidity and sliding velocity is evaluated.
Patent
Mitigation of biomolecular adsorption with hydrophilic polymer additives
TL;DR: In this paper, surface adsorption to the microfluidic device surfaces can be passively and actively mitigated by mixing certain hydrophilic polymers (organic polymers with repeating hydrophilic groups) with the sample liquid during or prior to relevant micro fluid operation.
References
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Book
CRC Handbook of Chemistry and Physics
TL;DR: CRC handbook of chemistry and physics, CRC Handbook of Chemistry and Physics, CRC handbook as discussed by the authors, CRC Handbook for Chemistry and Physiology, CRC Handbook for Physics,
Journal ArticleDOI
Rapid prototyping of microfluidic systems in poly(dimethylsiloxane)
TL;DR: A procedure that makes it possible to design and fabricate microfluidic systems in an elastomeric material poly(dimethylsiloxane) (PDMS) in less than 24 h by fabricating a miniaturized capillary electrophoresis system is described.
Journal ArticleDOI
Fabrication of microfluidic systems in poly(dimethylsiloxane)
J.C. McDonald,David C. Duffy,Janelle R. Anderson,Daniel T. Chiu,Hongkai Wu,Olivier Schueller,George M. Whitesides +6 more
TL;DR: Fabrication of microfluidic devices in poly(dimethylsiloxane) (PDMS) by soft lithography provides faster, less expensive routes to devices that handle aqueous solutions.
Journal ArticleDOI
A Sequencing Method Based on Real-Time Pyrophosphate
Journal ArticleDOI
Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip
TL;DR: In this article, the authors demonstrated a miniaturized system for sample handling and separation using electrophoresis-based separations of amino acids with up to 75,000 theoretical plates in about 15 seconds.