Journal ArticleDOI
Potential virulence factors of Proteus bacilli.
TLDR
The genus Proteus, which contains bacteria considered now to belong to the opportunistic pathogens, has its most characteristic attribute, swarming growth, enabling them to colonize and survive in higher organisms.Abstract:
The object of this review is the genus Proteus, which contains bacteria considered now to belong to the opportunistic pathogens. Widely distributed in nature (in soil, water, and sewage), Proteus species play a significant ecological role. When present in the niches of higher macroorganisms, these species are able to evoke pathological events in different regions of the human body. The invaders (Proteus mirabilis, P. vulgaris, and P. penneri) have numerous factors including fimbriae, flagella, outer membrane proteins, lipopolysaccharide, capsule antigen, urease, immunoglobulin A proteases, hemolysins, amino acid deaminases, and, finally, the most characteristic attribute of Proteus, swarming growth, enabling them to colonize and survive in higher organisms. All these features and factors are described and commented on in detail. The questions important for future investigation of these facultatively pathogenic microorganisms are also discussed.read more
Citations
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Supplementing capsaicin with chitosan-based films enhanced the anti-quorum sensing, antimicrobial, antioxidant, transparency, elasticity and hydrophobicity
Lalehan Akyuz,Murat Kaya,Muhammad Mujtaba,Sedef Ilk,Idris Sargin,Asier M. Salaberria,Jalel Labidi,Yavuz Selim Cakmak,Cemil Işlek +8 more
TL;DR: Capsaicin, a plant alkaloid with high antioxidative, anti-inflammatory, antiobesity, anticancer and analgesic properties, was used in the film technology for the first time and a continuous improvement was recorded in anti-quorum sensing and antimicrobial activities, antioxidative and hydrophobicity with increasing concentration of capsaicin in thefilm.
Journal ArticleDOI
Growth and aroma contribution of Microbacterium foliorum, Proteus vulgaris and Psychrobacter sp. during ripening in a cheese model medium
TL;DR: P. vulgaris, a Gram-negative bacterium naturally present on the surface of ripened cheeses, could produce high concentrations of flavour compounds from amino acid degradation during the ripening process and could be a useful organism for producing natural flavours as dairy ingredients.
Journal ArticleDOI
Comparison of antibiotic resistance patterns in collections of Escherichia coli and Proteus mirabilis uropathogenic strains
TL;DR: The aim of this study was to compare the antibiotic resistance of 141 clinical and 42 laboratory P. mirabilis strains and 129 clinical (Poland) uropathogenic E. coli strains to find out the proportion of unique versus diverse patterns in Swedish clinical and Laboratory P.mirabilis strain collections.
Journal ArticleDOI
Laser interferometric and cultivation methods for measurement of colistin/ampicilin and saponin interactions with smooth and rough of Proteus mirabilis lipopolysaccharides and cells.
TL;DR: The laser interferometric method is a useful tool for studies of lipopolysaccharide-antibiotic interactions even if the tested substances are not fully soluble in water.
Journal ArticleDOI
Regulation of flhDC expression in Proteus mirabilis.
TL;DR: Transposon insertions located 325 and 740 base pairs upstream of the transcriptional start site of the flhDC operon resulted in cells that initiated swarming 1.5h earlier than wild-type and exhibited a 2-2.5-fold greater swarming velocity.
References
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Journal ArticleDOI
Molecular basis of bacterial outer membrane permeability.
Hiroshi Nikaido,Martti Vaara +1 more
TL;DR: It is becoming increasingly clear that the outer membrane is very important in the physiology of gram-negative bacteria in making them resistant to host defense factors such as lysozyme, P-lysin, and various leukocyte proteins.
Journal ArticleDOI
Agents that increase the permeability of the outer membrane.
TL;DR: Chelators (such as EDTA, nitrilotriacetic acid, and sodium hexametaphosphate), which disintegrate the outer membrane by removing Mg2+ and Ca2+, are effective and valuable permeabilizers.
Journal ArticleDOI
Bacterial endotoxin: molecular relationships of structure to activity and function.
E. T. Rietschel,Teruo Kirikae,F U Schade,Uwe Mamat,Schmidt G,Harald Loppnow,Artur J. Ulmer,Ulrich Zähringer,Ulrich Seydel,F Di Padova +9 more
TL;DR: The biological analysis of synthetic lipid A partial structures proved that the expression of endotoxic activity depends on a unique primary structure and a peculiar endotoxic conformation, and molecular and submolecular details of the specificity of the interaction of lipid A with responsive host cells are determined.
Journal ArticleDOI
Virulence factors in Escherichia coli urinary tract infection.
TL;DR: This review summarizes the virtual explosion of information regarding the epidemiology, biochemistry, mechanisms of action, and genetic basis of these urovirulence factors that has occurred in the past decade and identifies areas in need of further study.
Journal ArticleDOI
Molecular biology of microbial ureases.
TL;DR: The crystal structure of the K. aerogenes enzyme has been determined and provides important insight into the mechanism of catalysis, and accessory genes have been shown to be required for activation of urease apoprotein, and roles for the accessory proteins in metallocenter assembly have been proposed.
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