Journal ArticleDOI
Psychobiotics: an emerging treatment in stress-related disorders.
Citations
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The gut microbiome in psychiatry: A primer for clinicians.
Michael Van Ameringen,Jasmine Turna,Beth Patterson,Amy Pipe,Amy Pipe,Randi Q. Mao,Rebecca Anglin,Michael G. Surette +7 more
TL;DR: Although there is a clear need for additional studies to elucidate the gut microbiome's role in psychiatric disorders, there is an even greater need for well‐designed, appropriately controlled studies to truly impact the field.
Journal ArticleDOI
Microbiota-Gut-Brain Axis, Part 1: An Integrated System of Immunological, Neural, and Hormonal Signals.
Journal ArticleDOI
Microbiota in Neuropsychiatry, Part 3: Psychobiotics as Modulators of Mood Disorders.
TL;DR: Research has emerged that suggests potential therapeutic approaches to modulate and stabilize the gut microbiota and to restore its healthy composition from dysbiotic states in various conditions, such as mood disorders.
References
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Journal ArticleDOI
A human gut microbial gene catalogue established by metagenomic sequencing
Junjie Qin,Ruiqiang Li,Jeroen Raes,Manimozhiyan Arumugam,Kristoffer Sølvsten Burgdorf,Chaysavanh Manichanh,Trine Nielsen,Nicolas Pons,Florence Levenez,Takuji Yamada,Daniel R. Mende,Junhua Li,Junming Xu,Shaochuan Li,Dongfang Li,Jianjun Cao,Bo Wang,Huiqing Liang,Huisong Zheng,Yinlong Xie,Julien Tap,Patricia Lepage,Marcelo Bertalan,Jean-Michel Batto,Torben Hansen,Denis Le Paslier,Allan Linneberg,H. Bjørn Nielsen,Eric Pelletier,Pierre Renault,Thomas Sicheritz-Pontén,Keith Turner,Hongmei Zhu,Chang Yu,Shengting Li,Min Jian,Yan Zhou,Yingrui Li,Xiuqing Zhang,Songgang Li,Nan Qin,Huanming Yang,Jian Wang,Søren Brunak,Joël Doré,Francisco Guarner,Karsten Kristiansen,Oluf Pedersen,Julian Parkhill,Jean Weissenbach,Peer Bork,S. Dusko Ehrlich,Jun Wang +52 more
TL;DR: The Illumina-based metagenomic sequencing, assembly and characterization of 3.3 million non-redundant microbial genes, derived from 576.7 gigabases of sequence, from faecal samples of 124 European individuals are described, indicating that the entire cohort harbours between 1,000 and 1,150 prevalent bacterial species and each individual at least 160 such species.
Journal ArticleDOI
Diversity of the human intestinal microbial flora.
Paul B. Eckburg,Elisabeth M. Bik,Charles N. Bernstein,Elizabeth Purdom,Les Dethlefsen,Michael Sargent,Steven R. Gill,Karen E. Nelson,David A. Relman,David A. Relman,David A. Relman +10 more
TL;DR: A majority of the bacterial sequences corresponded to uncultivated species and novel microorganisms, and significant intersubject variability and differences between stool and mucosa community composition were discovered.
Journal ArticleDOI
Enterotypes of the human gut microbiome
Manimozhiyan Arumugam,Jeroen Raes,Eric Pelletier,Denis Le Paslier,Takuji Yamada,Daniel R. Mende,Gabriel Fernandes,Julien Tap,Thomas Brüls,Jean-Michel Batto,Marcelo Bertalan,Natalia Borruel,Francesc Casellas,Leyden Fernández,Laurent Gautier,Torben Hansen,Masahira Hattori,Tetsuya Hayashi,Michiel Kleerebezem,Ken Kurokawa,Marion Leclerc,Florence Levenez,Chaysavanh Manichanh,H. Bjørn Nielsen,Trine Nielsen,Nicolas Pons,Julie Poulain,Junjie Qin,Thomas Sicheritz-Pontén,Sebastian Tims,David Torrents,Edgardo Ugarte,Erwin G. Zoetendal,Jun Wang,Francisco Guarner,Oluf Pedersen,Willem M. de Vos,Søren Brunak,Joël Doré,Jean Weissenbach,S. Dusko Ehrlich,Peer Bork +41 more
TL;DR: Three robust clusters (referred to as enterotypes hereafter) are identified that are not nation or continent specific and confirmed in two published, larger cohorts, indicating that intestinal microbiota variation is generally stratified, not continuous.
Journal ArticleDOI
Metagenomic Analysis of the Human Distal Gut Microbiome
Steven R. Gill,Mihai Pop,Robert T. DeBoy,Paul B. Eckburg,Paul B. Eckburg,Peter J. Turnbaugh,Buck S. Samuel,Jeffrey I. Gordon,David A. Relman,David A. Relman,Claire M. Fraser-Liggett,Karen E. Nelson +11 more
TL;DR: Using metabolic function analyses of identified genes, the human genome is compared with the average content of previously sequenced microbial genomes and humans are superorganisms whose metabolism represents an amalgamation of microbial and human attributes.
Journal ArticleDOI
Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns
Maria Gloria Dominguez-Bello,Elizabeth K. Costello,Elizabeth K. Costello,Monica Contreras,Magda Magris,Glida Hidalgo,Noah Fierer,Rob Knight +7 more
TL;DR: It is found that in direct contrast to the highly differentiated communities of their mothers, neonates harbored bacterial communities that were undifferentiated across multiple body habitats, regardless of delivery mode.
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