Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism.
Amna Sirelkhatim,Shahrom Mahmud,Azman Seeni,Noor Haida Mohamad Kaus,Ling Chuo Ann,Siti Khadijah Mohd Bakhori,Habsah Hasan,Dasmawati Mohamad +7 more
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This review covered ZnO-NPs antibacterial activity including testing methods, impact of UV illumination,ZnO particle properties (size, concentration, morphology, and defects), particle surface modification, and minimum inhibitory concentration.Abstract:
Antibacterial activity of zinc oxide nanoparticles (ZnO-NPs) has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. ZnO-NPs exhibit attractive antibacterial properties due to increased specific surface area as the reduced particle size leading to enhanced particle surface reactivity. ZnO is a bio-safe material that possesses photo-oxidizing and photocatalysis impacts on chemical and biological species. This review covered ZnO-NPs antibacterial activity including testing methods, impact of UV illumination, ZnO particle properties (size, concentration, morphology, and defects), particle surface modification, and minimum inhibitory concentration. Particular emphasize was given to bactericidal and bacteriostatic mechanisms with focus on generation of reactive oxygen species (ROS) including hydrogen peroxide (H2O2), OH− (hydroxyl radicals), and O2 −2 (peroxide). ROS has been a major factor for several mechanisms including cell wall damage due to ZnO-localized interaction, enhanced membrane permeability, internalization of NPs due to loss of proton motive force and uptake of toxic dissolved zinc ions. These have led to mitochondria weakness, intracellular outflow, and release in gene expression of oxidative stress which caused eventual cell growth inhibition and cell death. In some cases, enhanced antibacterial activity can be attributed to surface defects on ZnO abrasive surface texture. One functional application of the ZnO antibacterial bioactivity was discussed in food packaging industry where ZnO-NPs are used as an antibacterial agent toward foodborne diseases. Proper incorporation of ZnO-NPs into packaging materials can cause interaction with foodborne pathogens, thereby releasing NPs onto food surface where they come in contact with bad bacteria and cause the bacterial death and/or inhibition.read more
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Impact of Cu doping on ZnO nanoparticles phyto-chemically synthesized for improved antibacterial and photocatalytic activities
TL;DR: In this paper, the impact of Cu doping on the structure, morphology, and optical properties of ZnO nanoparticles was evaluated using XRD, SEM, and UV-vis spectroscopy, respectively.
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Tuning crystallization and morphology of zinc oxide with polyvinylpyrrolidone: Formation mechanisms and antimicrobial activity.
TL;DR: This study reports a simple water-based chemical precipitation method to produce unique bowtie-, flower-, and nest-shaped ZnO particles using zinc nitrate and urea in the presence of polyvinylpyrrolidone (PVP) and shows that they exhibit similar bacterial killing efficacy towards Escherichia coli and Staphylococcus aureus.
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Effect of ZnO nanoparticles on the photochemical and electronic stability of P3HT used in polymer solar cells
Anthony Chapel,Anthony Chapel,Sadok Ben Dkhil,Sandrine Therias,Sandrine Therias,Jean-Luc Gardette,Jean-Luc Gardette,D Hannani,G. Poize,Meriem Gaceur,Syed Mujtaba Shah,Pascal Wong-Wah-Chung,Christine Videlot-Ackermann,Olivier Margeat,Agnès Rivaton,Agnès Rivaton,Jörg Ackermann +16 more
TL;DR: In this paper, the photochemical and electronic stability of poly(3-hexyl thiophene)/zinc oxide nanoparticle (P3HT/ZnO) interfaces is compared with device stability of hybrid bulk heterojunction solar cells under light soaking and dark storage.
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Structural, optical, cytotoxicity, and antimicrobial properties of MgO, ZnO and MgO/ZnO nanocomposite for biomedical applications
TL;DR: In this article, MgO nanoparticles were successfully fabricated and incubated inside ZnO NPs to form a nanocomposite for biomedical applications, which exhibited the antimicrobial properties against Escherichia coli and Staphylococcus aureus.
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TIO2 nanoparticle coatings with advanced antibacterial and hydrophilic properties prepared by flame aerosol synthesis and thermophoretic deposition
Gianluigi De Falco,Roberto Ciardiello,Mario Commodo,Pasquale Del Gaudio,Patrizia Minutolo,Amalia Porta,Andrea D’Anna +6 more
TL;DR: In this article, three different flame reactor configurations were designed in order to study the effect of particle size and film morphology on the performances of thin coatings of TiO2 nanoparticles by aerosol flame synthesis and direct thermophoretic deposition.
References
More filters
Journal ArticleDOI
A comprehensive review of zno materials and devices
Ümit Özgür,Ya. I. Alivov,C. Liu,A. Teke,Michael A. Reshchikov,Seydi Doğan,Vitaliy Avrutin,Sang-Jun Cho,Hadis Morkoç +8 more
TL;DR: The semiconductor ZnO has gained substantial interest in the research community in part because of its large exciton binding energy (60meV) which could lead to lasing action based on exciton recombination even above room temperature.
Journal ArticleDOI
Piezoelectric Nanogenerators Based on Zinc Oxide Nanowire Arrays
TL;DR: This approach has the potential of converting mechanical, vibrational, and/or hydraulic energy into electricity for powering nanodevices.
Journal ArticleDOI
Antimicrobial effects of silver nanoparticles
Jun Sung Kim,Eunye Kuk,Kyeong Nam Yu,Jong-Ho Kim,Sungjin Park,Hu Jang Lee,So Hyun Kim,Young Kyung Park,Yong Ho Park,Cheol Yong Hwang,Yong-Kwon Kim,Yoon-Sik Lee,Dae Hong Jeong,Myung-Haing Cho +13 more
TL;DR: The results suggest that Ag nanoparticles can be used as effective growth inhibitors in various microorganisms, making them applicable to diverse medical devices and antimicrobial control systems.
Journal ArticleDOI
Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram-negative bacterium Escherichia coli.
TL;DR: This is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and the results demonstrate thatsilver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
Journal ArticleDOI
Zinc oxide nanostructures: growth, properties and applications
TL;DR: In this paper, a review of various nanostructures of ZnO grown by the solid-vapour phase technique and their corresponding growth mechanisms is presented. And the application of nanobelts as nanosensors, nanocantilevers, field effect transistors and nanoresonators is demonstrated.