Journal ArticleDOI
Roles of glycodelin in modulating sperm function.
William S.B. Yeung,Kai-Fai Lee,Riitta Koistinen,Hannu Koistinen,Markku Seppälä,P.C. Ho,Philip C.N. Chiu +6 more
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TLDR
Different isoforms of glycodelin have different biological roles on sperm function, and they act in succession to contribute to the success of fertilization.About:
This article is published in Molecular and Cellular Endocrinology.The article was published on 2006-05-16. It has received 62 citations till now. The article focuses on the topics: Glycodelin & Acrosome reaction.read more
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Journal ArticleDOI
Molecular mechanisms of ovulation: co-ordination through the cumulus complex
TL;DR: This review focuses on the recent advances in understanding of molecular mechanisms that commence after the gonadotrophin surge and culminate with release of the oocyte.
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Proteomic Analysis of Seminal Plasma from Normal Volunteers and Post-Vasectomy Patients Identifies over 2000 Proteins and Candidate Biomarkers of the Urogenital System
Ihor Batruch,Irene Lecker,Irene Lecker,Daniel Kagedan,Daniel Kagedan,Christopher R. Smith,Christopher R. Smith,Brendan Mullen,Brendan Mullen,Ethan D. Grober,Ethan D. Grober,Kirk C. Lo,Kirk C. Lo,Eleftherios P. Diamandis,Eleftherios P. Diamandis,Keith Jarvi,Keith Jarvi +16 more
TL;DR: It is believed that proteins unique to Control or at lower abundance in PV have their origin in the testis and the epididymis, and these proteins may serve as candidate biomarkers for future studies of infertility and urogenital diseases.
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Sperm preparation: state-of-the-art--physiological aspects and application of advanced sperm preparation methods.
TL;DR: Techniques in this category are magnet-activated cell sorting, Annexin V-activated glass wool filtration, flow cytometry and picked spermatozoa for ICSI (PICSI) from HA-coated dishes and HA-containing media.
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Sugar‐coated sperm: Unraveling the functions of the mammalian sperm glycocalyx
Eillen Tecle,Pascal Gagneux +1 more
TL;DR: The sperm glycocalyx mediates numerous functions in the female reproductive tract, including the following: inhibition of premature capacitation; passage through the cervical mucus; protection from innate and adaptive female immunity; formation of the sperm reservoir; and masking sperm proteins involved in fertilization.
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Eukaryotic protein glycosylation: a primer for histochemists and cell biologists.
TL;DR: Following this educational survey, examples where known biological function is related to the glycan structures carried by proteins are given and mucins and their glycosylation patterns are considered as instructive proof-of-principle case.
References
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Preface to the IssueMolecular and Cellular Endocrinology: Special Issue: Endocrine Cell Lines
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Global Gene Profiling in Human Endometrium during the Window of Implantation
L.C. Kao,Suzana Tulac,Shalini C Lobo,Babek Imani,J. P. Yang,Ariane Germeyer,Kevin G. Osteen,Robert N. Taylor,Bruce A. Lessey,Linda C. Giudice +9 more
TL;DR: Global gene expression during the window of implantation (peak E2 and progesterone levels) in well characterized human endometrial biopsies timed to the LH surge is investigated, compared with the late proliferative phase ( peak E2 level) of the menstrual cycle.
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Natural Killer Cells in Pregnancy and Recurrent Pregnancy Loss: Endocrine and Immunologic Perspectives
TL;DR: NK cell populations, their changes in number and function in altered endocrine environments during the menstrual cycle and pregnancy, the current data on their potential role in unexplained recurrent pregnancy loss, and mechanisms for potential therapies targeted to NK cell function for this enigmatic disorder are reviewed.
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Novel signaling pathways involved in sperm acquisition of fertilizing capacity.
Pablo E. Visconti,V.A. Westbrook,Olga Chertihin,Ignacio A. Demarco,Susan B. Sleight,Alan B. Diekman +5 more
TL;DR: Recent progress is discussed in elucidating mechanisms which regulate sperm capacitation, which correlates with cholesterol efflux from the sperm plasma membrane, increased membrane fluidity, modulations in intracellular ion concentrations, hyperpolarization of the sperm Plasma membrane and increased protein tyrosine phosphorylation.