Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges.
TLDR
Among patients with pneumonia caused by SARS-CoV-2 (novel coronavirus pneumonia or Wuhan pneumonia), fever was the most common symptom, followed by cough, and bilateral lung involvement with ground-glass opacity was themost common finding from computed tomography images of the chest.Citations
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The Neutrophil-to-Monocyte Ratio and Lymphocyte-to-Neutrophil Ratio at Admission Predict In-Hospital Mortality in Mexican Patients with Severe SARS-CoV-2 Infection (Covid-19)
Salma A. Rizo-Téllez,Lucia A Méndez-García,Cruz Flores-Rebollo,Fernando Alba-Flores,Raúl Alcántara-Suárez,Aarón N. Manjarrez-Reyna,Neyla Baltazar-López,Verónica A. Hernández-Guzmán,José Israel León-Pedroza,Rogelio Zapata-Arenas,Antonio González-Chávez,Joselín Hernández-Ruiz,José D. Carrillo-Ruiz,Raúl Serrano-Loyola,Guadalupe Mercedes Lucia Guerrero-Avendaño,Galileo Escobedo +15 more
TL;DR: This study demonstrates for the first time that NMR and LNR are accurate predictors of in-hospital mortality at admission in patients with severe Covid-19.
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Evaluation of technology-based learning by dental students during the pandemic outbreak of coronavirus disease 2019.
TL;DR: Dental students demonstrated low‐moderate satisfaction and positive attitude toward TB‐learning and the quality of material presented to them during the pandemic outbreak of COVID‐19, indicating that integrating TB‐ learning into the dental education curriculum is an essential step in enhancing the acceptance ofTB‐learning in the future.
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Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions
Safaet Alam,Md. Moklesur Rahman Sarker,Sadia Afrin,Fahmida Tasnim Richi,Chao Zhao,Jin-Rong Zhou,Isa Naina Mohamed +6 more
TL;DR: A review of plant-based anti-COVID-19 clinical trials found in several scientific and authenticated databases is presented in this article, where the aim is to allow researchers and innovators to identify promising and prospective anti-Covari-19 agents in clinical trials to establish them as novel therapies to address this unwanted pandemic.
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Micro-RNAs in the regulation of immune response against SARS COV-2 and other viral infections.
Tareq Abu-Izneid,Noora Alhajri,Abdallah Mohammad Ibrahim,Md. Noushad Javed,Khairi Mustafa Salem,Faheem Hyder Pottoo,Mohammad Amjad Kamal,Mohammad Amjad Kamal +7 more
TL;DR: The biological roles and effects of miRNAs on SARS-CoV-2 life-cycle and pathogenicity are described, and the modulation of the immune system with micro-RNAs which would serve as a new foundation for the treatment of Sars-COV2 and other viral infections are discussed.
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Analysis of 2019-nCoV receptor ACE2 expression in different tissues and its significance study
TL;DR: The expression of ACE2 was the highest in the small intestines, higher in tissues such as salivary glands in the testicular, kidney, heart, thyroid and adipose tissues, while the expression ofACE2 was lower in tissuessuch as the spleen, brain, muscle, pituitary, and skin.
References
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Chaolin Huang,Yeming Wang,Xingwang Li,Lili Ren,Jianping Zhao,Yi Hu,Li Zhang,Guohui Fan,Jiuyang Xu,Xiaoying Gu,Zhenshun Cheng,Ting Yu,Jia'an Xia,Yuan Wei,Wenjuan Wu,Xuelei Xie,Wen Yin,Li Hui,Min Liu,Yan Xiao,Hong Gao,Li Guo,Jungang Xie,Guang-Fa Wang,Rongmeng Jiang,Zhancheng Gao,Qi Jin,Jianwei Wang,Bin Cao +28 more
TL;DR: The epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of patients with laboratory-confirmed 2019-nCoV infection in Wuhan, China, were reported.
Journal ArticleDOI
A Novel Coronavirus from Patients with Pneumonia in China, 2019.
Na Zhu,Dingyu Zhang,Wenling Wang,Xingwang Li,Bo Yang,Jingdong Song,Xiang Zhao,Baoying Huang,Weifeng Shi,Roujian Lu,Peihua Niu,Faxian Zhan,Xuejun Ma,Dayan Wang,Wenbo Xu,Wenbo Xu,Guizhen Wu,George F. Gao,Wenjie Tan +18 more
TL;DR: Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans.
Journal ArticleDOI
A pneumonia outbreak associated with a new coronavirus of probable bat origin
Peng Zhou,Xing-Lou Yang,Xian Guang Wang,Ben Hu,Lei Zhang,Wei Zhang,Hao Rui Si,Yan Zhu,Bei Li,Chao Lin Huang,Hui-Dong Chen,Jing Chen,Yun Luo,Hua Guo,Ren Di Jiang,Meiqin Liu,Ying Chen,Xu Rui Shen,Xi Wang,Xiao Shuang Zheng,Kai Zhao,Quanjiao Chen,Fei Deng,Lin Lin Liu,Bing Yan,Fa Xian Zhan,Yan-Yi Wang,Gengfu Xiao,Zhengli Shi +28 more
TL;DR: Identification and characterization of a new coronavirus (2019-nCoV), which caused an epidemic of acute respiratory syndrome in humans in Wuhan, China, and it is shown that this virus belongs to the species of SARSr-CoV, indicates that the virus is related to a bat coronav virus.
Journal ArticleDOI
Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
Dawei Wang,Bo Hu,Chang Hu,Fangfang Zhu,Xing Liu,Jing Zhang,Binbin Wang,Hui Xiang,Zhenshun Cheng,Yong Xiong,Yan Zhao,Yirong Li,Xinghuan Wang,Zhiyong Peng +13 more
TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
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